| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Ice Age: Dawn of the Dinosaurs | $79,409 | -7.1% | 6 | -1 | $13,234 | $227,548 | 2 | 20th Century Fox International | false | false |
| 2 | - | The Hangover | $56,676 | - | 6 | - | $9,446 | $56,676 | 1 | Warner Bros. | true | false |
| 3 | 2 | Omar & Salma | $41,040 | -25.6% | 8 | - | $5,130 | $492,973 | 5 | N/A | false | false |
| 4 | 4 | The Proposal | $23,679 | -22.5% | 6 | - | $3,946 | $185,511 | 4 | Walt Disney Pictures | false | false |
| 5 | - | Bobbos | $23,239 | - | 7 | - | $3,319 | $23,239 | 1 | N/A | true | false |
| 6 | 3 | Transformers: Revenge of the Fallen | $22,033 | -44.8% | 7 | - | $3,147 | $192,867 | 3 | United International Pictures | false | false |
| 7 | 7 | Up | $7,832 | -8.7% | 6 | - | $1,305 | $129,449 | 5 | Walt Disney Pictures | false | false |
| 8 | 5 | I Hate Valentine's Day | $7,832 | -36% | 5 | - | $1,566 | $28,436 | 2 | Jaguar Film International Distribution | false | false |
| 9 | 8 | The Last House on the Left | $4,754 | -39.1% | 2 | -1 | $2,377 | $17,046 | 2 | N/A | false | false |
| 10 | 6 | Dukan Shehata | $4,460 | -56% | 4 | -1 | $1,115 | $38,509 | 3 | N/A | false | false |
| 11 | 9 | My Life in Ruins | $3,930 | -47% | 1 | -3 | $3,930 | $33,746 | 3 | Prime Pictures | false | false |
| 12 | 11 | The Taking of Pelham 123 | $3,767 | -23.4% | 2 | - | $1,883 | $70,663 | 5 | Sony Pictures Releasing | false | false |
| 13 | 12 | State of Play | $2,957 | -30.4% | 1 | - | $2,957 | $80,416 | 7 | United International Pictures | false | false |
| 14 | - | JCVD | $2,405 | - | 5 | - | $481 | $2,405 | 1 | N/A | true | false |
| 15 | 10 | Obsessed | $1,561 | -76.4% | 3 | -2 | $520 | $13,203 | 2 | Sony Pictures Releasing | false | false |
| 16 | 16 | I Love You, Man | $1,121 | +2.3% | 1 | - | $1,121 | $73,962 | 7 | United International Pictures | false | false |
| 17 | 15 | Angels & Demons | $1,050 | -37.4% | 2 | - | $525 | $187,681 | 9 | Sony Pictures Releasing | false | false |
| 18 | 17 | Terminator Salvation | $989 | +0.4% | 1 | -1 | $989 | $84,726 | 8 | N/A | false | false |
| 19 | - | Coraline | $790 | - | 1 | - | $790 | $52,747 | 9 | United International Pictures | false | false |
| 20 | 19 | Defiance | $750 | +34.2% | 2 | - | $375 | $28,805 | 9 | N/A | false | false |
| 21 | 13 | Two Lovers | $593 | -81.7% | 2 | -2 | $296 | $29,941 | 5 | N/A | false | false |
| 22 | 20 | Franklyn | $489 | -2.8% | 3 | - | $163 | $5,442 | 4 | Italian International Film | false | false |
| 23 | 23 | Hannah Montana: The Movie | $265 | +14.7% | 1 | - | $265 | $126,140 | 14 | Walt Disney Pictures | false | false |
| 24 | 21 | It's Alive | $262 | +6.9% | 1 | - | $262 | $23,983 | 12 | Italian International Film | false | false |
| 25 | 24 | Make It Happen | $126 | -42.7% | 1 | - | $126 | $7,879 | 4 | N/A | false | false |
