| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Ice Age: Dawn of the Dinosaurs | $937,115 | - | 91 | - | $10,297 | $937,115 | 1 | NuMetro Distribution | true | false |
| 2 | 1 | Transformers: Revenge of the Fallen | $293,435 | -59% | 97 | - | $3,025 | $1,362,167 | 2 | United International Pictures | false | false |
| 3 | - | Knowing | $192,719 | - | 73 | - | $2,639 | $192,719 | 1 | United International Pictures | true | false |
| 4 | 2 | The Hangover | $140,544 | -20.1% | 55 | - | $2,555 | $796,366 | 3 | NuMetro Distribution | false | false |
| 5 | 3 | Night at the Museum: Battle of the Smithsonian | $71,002 | -37.7% | 78 | - | $910 | $1,465,786 | 7 | NuMetro Distribution | false | false |
| 6 | 5 | Ghosts of Girlfriends Past | $38,551 | -32.8% | 42 | -2 | $917 | $936,277 | 8 | NuMetro Distribution | false | false |
| 7 | 7 | Obsessed | $34,297 | -22.2% | 24 | - | $1,429 | $174,205 | 3 | Ster-Kinekor Pictures | false | false |
| 8 | - | Kambakkht Ishq | $28,943 | - | 6 | - | $4,823 | $28,943 | 1 | NuMetro Distribution | true | false |
| 9 | 4 | Terminator Salvation | $25,913 | -58.4% | 53 | -26 | $488 | $827,834 | 5 | Ster-Kinekor Pictures | false | false |
| 10 | 6 | Drag Me to Hell | $23,132 | -49.7% | 30 | -10 | $771 | $291,007 | 4 | NuMetro Distribution | false | false |
| 11 | 8 | Duplicity | $22,517 | -40.4% | 34 | -9 | $662 | $585,862 | 6 | United International Pictures | false | false |
| 12 | 9 | State of Play | $22,419 | -38.8% | 23 | -8 | $974 | $280,360 | 4 | United International Pictures | false | false |
| 13 | - | Next Day Air | $18,577 | - | 15 | - | $1,238 | $18,577 | 1 | NuMetro Distribution | true | false |
| 14 | - | The Brothers Bloom | $11,710 | - | 10 | - | $1,171 | $11,710 | 1 | Ster-Kinekor Pictures | true | false |
| 15 | 10 | Angels & Demons | $7,537 | -67.5% | 13 | -21 | $579 | $1,052,036 | 8 | Ster-Kinekor Pictures | false | false |
| 16 | 16 | Welcome to the Sticks | $6,310 | -18.5% | 4 | - | $1,577 | $19,175 | 2 | Ster-Kinekor Pictures | false | false |
| 17 | 14 | Sunshine Cleaning | $5,703 | -38.2% | 10 | - | $570 | $68,600 | 4 | United International Pictures | false | false |
| 18 | 15 | Hannah Montana: The Movie | $3,222 | -58.5% | 7 | -9 | $460 | $748,758 | 10 | Ster-Kinekor Pictures | false | false |
| 19 | 17 | White Wedding | $2,946 | -58.2% | 3 | -7 | $982 | $617,455 | 10 | Ster-Kinekor Pictures | false | false |
| 20 | - | The Uninvited | $1,930 | - | 5 | - | $386 | $46,581 | 6 | United International Pictures | false | false |
| 21 | 24 | The Reader | $1,488 | -29.2% | 3 | -1 | $496 | $339,802 | 15 | Ster-Kinekor Pictures | false | false |
| 22 | 21 | Star Trek | $1,409 | -59% | 5 | -6 | $281 | $383,493 | 9 | United International Pictures | false | false |
| 23 | - | The Unborn | $1,162 | - | 4 | - | $290 | $71,395 | 8 | United International Pictures | false | false |
