| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Ice Age: Dawn of the Dinosaurs | $37,756 | -7.4% | 4 | +1 | $9,439 | $90,116 | 2 | 20th Century Fox International | false | false |
| 2 | 1 | Transformers: Revenge of the Fallen | $35,708 | -14.8% | 8 | - | $4,463 | $197,088 | 3 | United International Pictures | false | false |
| 3 | 3 | The Proposal | $35,384 | +6% | 2 | - | $17,692 | $113,515 | 3 | Walt Disney Pictures | false | false |
| 4 | 4 | Night at the Museum: Battle of the Smithsonian | $15,015 | +7.9% | 3 | - | $5,005 | $240,222 | 8 | 20th Century Fox International | false | false |
| 5 | 5 | Up | $10,814 | +9.1% | 2 | - | $5,407 | $85,520 | 6 | Walt Disney Pictures | false | false |
| 6 | 6 | The Taking of Pelham 123 | $10,803 | +28.5% | 2 | -2 | $5,401 | $104,354 | 5 | Sony Pictures Releasing | false | false |
| 7 | 7 | Angels & Demons | $8,504 | +15.8% | 2 | - | $4,252 | $260,742 | 9 | Sony Pictures Releasing | false | false |
| 8 | 8 | State of Play | $4,679 | +13.9% | 3 | - | $1,559 | $82,046 | 8 | United International Pictures | false | false |
| 9 | 10 | I Love You, Man | $3,073 | +15.7% | 2 | -1 | $1,536 | $23,576 | 13 | United International Pictures | false | false |
| 10 | 9 | X-Men Origins: Wolverine | $2,282 | -18.3% | 2 | -1 | $1,141 | $209,143 | 11 | 20th Century Fox International | false | false |
| 11 | 11 | The Uninvited | $1,932 | +15.8% | 1 | - | $1,932 | $78,193 | 11 | United International Pictures | false | false |
| 12 | 13 | Coraline | $379 | -36.2% | 2 | -1 | $189 | $16,876 | 6 | United International Pictures | false | false |
| 13 | 12 | Knowing | $216 | -70.9% | 2 | - | $108 | $264,358 | 12 | - | false | false |
