| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Transformers: Revenge of the Fallen | $41,899 | -53.2% | 8 | - | $5,237 | $147,526 | 2 | United International Pictures | false | false |
| 2 | - | Ice Age: Dawn of the Dinosaurs | $40,777 | - | 3 | - | $13,592 | $40,777 | 1 | 20th Century Fox International | true | false |
| 3 | 2 | The Proposal | $33,384 | +36.4% | 2 | - | $16,692 | $67,251 | 2 | Walt Disney Pictures | false | false |
| 4 | 3 | Night at the Museum: Battle of the Smithsonian | $13,916 | -21.7% | 3 | -2 | $4,638 | $220,272 | 7 | 20th Century Fox International | false | false |
| 5 | 5 | Up | $9,912 | -16.1% | 2 | - | $4,956 | $71,624 | 5 | Walt Disney Pictures | false | false |
| 6 | 4 | The Taking of Pelham 123 | $8,406 | -47.3% | 4 | -1 | $2,101 | $90,399 | 4 | Sony Pictures Releasing | false | false |
| 7 | 6 | Angels & Demons | $7,342 | -9.6% | 2 | - | $3,671 | $249,244 | 8 | Sony Pictures Releasing | false | false |
| 8 | 9 | State of Play | $4,108 | +113.4% | 3 | - | $1,369 | $75,553 | 7 | United International Pictures | false | false |
| 9 | 7 | X-Men Origins: Wolverine | $2,792 | -58.7% | 3 | - | $930 | $205,613 | 10 | 20th Century Fox International | false | false |
| 10 | 10 | I Love You, Man | $2,657 | +77.5% | 3 | - | $885 | $19,104 | 12 | United International Pictures | false | false |
| 11 | 11 | The Uninvited | $1,668 | +45.5% | 1 | - | $1,668 | $75,296 | 10 | United International Pictures | false | false |
| 12 | 8 | Knowing | $742 | -72.5% | 2 | - | $371 | $264,137 | 11 | - | false | false |
| 13 | 12 | Coraline | $594 | -12.6% | 3 | - | $198 | $16,248 | 5 | United International Pictures | false | false |
