| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Transformers: Revenge of the Fallen | $566,091 | - | 84 | - | $6,739 | $674,661 | 1 | United International Pictures | true | false |
| 2 | 1 | Up | $507,332 | -8.5% | 63 | -11 | $8,052 | $2,002,518 | 3 | Walt Disney Pictures | false | false |
| 3 | 2 | Terminator Salvation | $67,287 | -38.2% | 43 | -6 | $1,564 | $870,979 | 4 | Sony Pictures Releasing | false | false |
| 4 | 3 | Angels & Demons | $55,273 | -11.6% | 37 | -6 | $1,493 | $2,137,587 | 7 | Sony Pictures Releasing | false | false |
| 5 | 5 | Knowing | $40,404 | -4% | 18 | -6 | $2,244 | $635,725 | 6 | N/A | false | false |
| 6 | 4 | Night at the Museum: Battle of the Smithsonian | $34,114 | -37.5% | 32 | -7 | $1,066 | $1,292,214 | 6 | 20th Century Fox International | false | false |
| 7 | - | Teresa: Crucificada por amar | $15,081 | - | 9 | - | $1,675 | $39,495 | 2 | N/A | false | false |
| 8 | 6 | The Accidental Husband | $10,472 | -62.7% | 14 | -11 | $748 | $45,833 | 2 | Walt Disney Pictures | false | false |
| 9 | 8 | Duplicity | $9,019 | -17.1% | 6 | -1 | $1,503 | $122,063 | 5 | United International Pictures | false | false |
| 10 | - | Grace Is Gone | $5,769 | - | 2 | - | $2,884 | $5,769 | 1 | N/A | true | false |
| 11 | 7 | Blackout 2009 Re-release | $4,059 | -65.9% | 4 | -4 | $1,014 | $19,423 | 2 | N/A | false | false |
| 12 | 11 | Paris | $3,161 | -4.4% | 1 | -1 | $3,161 | $84,534 | 8 | N/A | false | false |
| 13 | 12 | Hannah Montana: The Movie | $2,816 | -9.4% | 1 | -13 | $2,816 | $1,056,206 | 9 | Walt Disney Pictures | false | false |
| 14 | 13 | Fast & Furious | $1,118 | -56% | 1 | -3 | $1,118 | $344,211 | 8 | United International Pictures | false | false |
| 15 | 10 | Vicky Cristina Barcelona | $872 | -73.7% | 1 | -1 | $872 | $220,130 | 9 | N/A | false | false |
| 16 | 9 | Star Trek | $537 | -89.6% | 1 | -6 | $537 | $273,992 | 8 | United International Pictures | false | false |
| 17 | 17 | X-Men Origins: Wolverine | $525 | -30.2% | 1 | - | $525 | $993,660 | 9 | 20th Century Fox International | false | false |
| 18 | 16 | 17 Again | $280 | -81.4% | 2 | - | $140 | $136,867 | 10 | Warner Bros. | false | false |
