| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Omar & Salma | $111,179 | - | 8 | - | $13,897 | $111,179 | 1 | N/A | true | false |
| 2 | - | Up | $21,307 | - | 6 | - | $3,551 | $21,307 | 1 | Walt Disney Pictures | true | false |
| 3 | - | The Taking of Pelham 123 | $19,601 | - | 6 | - | $3,266 | $19,601 | 1 | Sony Pictures Releasing | true | false |
| 4 | 1 | Angels & Demons | $11,651 | +38.7% | 7 | - | $1,664 | $156,463 | 5 | Sony Pictures Releasing | false | false |
| 5 | 2 | State of Play | $7,393 | +11.8% | 6 | -1 | $1,232 | $49,783 | 3 | United International Pictures | false | false |
| 6 | 3 | Night at the Museum: Battle of the Smithsonian | $7,244 | +25.2% | 6 | - | $1,207 | $61,493 | 4 | 20th Century Fox International | false | false |
| 7 | - | Two Lovers | $6,054 | - | 5 | - | $1,210 | $6,054 | 1 | N/A | true | false |
| 8 | 4 | I Love You, Man | $5,932 | +48.4% | 4 | - | $1,483 | $63,035 | 3 | United International Pictures | false | false |
| 9 | 5 | Terminator Salvation | $4,699 | +18% | 3 | -1 | $1,566 | $66,932 | 4 | N/A | false | false |
| 10 | - | Crank: High Voltage | $4,649 | - | 4 | - | $1,162 | $4,649 | 1 | N/A | true | false |
| 11 | 6 | Coraline | $3,783 | +54.7% | 1 | -1 | $3,783 | $44,574 | 5 | United International Pictures | false | false |
| 12 | 7 | X-Men Origins: Wolverine | $2,065 | +9.8% | 2 | -3 | $1,032 | $82,325 | 7 | 20th Century Fox International | false | false |
| 13 | 16 | Knowing | $627 | +54.8% | 1 | - | $627 | $112,379 | 9 | Jaguar Film International Distribution | false | false |
| 14 | 8 | New in Town | $543 | -67.1% | 2 | -1 | $271 | $16,744 | 4 | N/A | false | false |
| 15 | 12 | Duplicity | $414 | -35.8% | 1 | -1 | $414 | $127,379 | 9 | United International Pictures | false | false |
| 16 | 9 | Finding Amanda | $399 | -74.7% | 3 | -2 | $133 | $7,525 | 3 | Italian International Film | false | false |
| 17 | 13 | Boogeyman 2 | $397 | -35.1% | 1 | -1 | $397 | $3,748 | 3 | N/A | false | false |
| 18 | 14 | Defiance | $387 | -31.3% | 2 | - | $193 | $24,945 | 5 | N/A | false | false |
| 19 | 11 | Skirt Day | $352 | -48.2% | 1 | -2 | $352 | $5,508 | 4 | Prime Pictures | false | false |
| 20 | 25 | It's Alive | $280 | +67.7% | 1 | - | $280 | $22,650 | 8 | Italian International Film | false | false |
| 21 | 17 | Hannah Montana: The Movie | $267 | -30.3% | 3 | - | $89 | $124,960 | 10 | Walt Disney Pictures | false | false |
| 22 | 26 | Charbel | $220 | +37.5% | 2 | -1 | $110 | $314,551 | 19 | Italian International Film | false | false |
| 23 | 24 | Shola Cohen | $151 | -12.7% | 1 | -1 | $151 | $14,942 | 10 | N/A | false | false |
| 24 | 27 | Frozen River | $123 | -16.3% | 1 | - | $123 | $7,389 | 6 | Prime Pictures | false | false |
| 25 | 23 | Revolver 2007 Re-release | $107 | -42.8% | 1 | -1 | $107 | $7,691 | 5 | Italian International Film | false | false |
| 26 | 19 | Ramadan Mabrouk Abul-Alamein Hamouda | $27 | -91% | 1 | -1 | $27 | $51,363 | 10 | N/A | false | false |
