| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Night at the Museum: Battle of the Smithsonian | $160,711 | -50.7% | 94 | +1 | $1,709 | $597,734 | 2 | Gemini Films | false | false |
| 2 | 2 | Angels & Demons | $118,189 | -53.6% | 100 | - | $1,181 | $1,431,656 | 3 | Sony Pictures Releasing | false | false |
| 3 | 3 | Star Trek | $12,716 | -41.7% | 72 | -1 | $176 | $394,380 | 4 | Paramount Pictures International | false | false |
| 4 | 4 | Observe and Report | $5,541 | -53.6% | 29 | - | $191 | $59,488 | 3 | Warner Bros. | false | false |
| 5 | 5 | X-Men Origins: Wolverine | $3,437 | -60.8% | 28 | -18 | $122 | $475,859 | 5 | 20th Century Fox International | false | false |
| 6 | 6 | The Boat That Rocked | $3,081 | -17.6% | 9 | -9 | $342 | $81,400 | 4 | Universal Pictures International (UPI) | false | false |
| 7 | 8 | I Love You, Man | $2,824 | -2.2% | 4 | -2 | $706 | $241,141 | 8 | Paramount Pictures International | false | false |
| 8 | 7 | Coraline | $2,092 | -35.2% | 19 | -6 | $110 | $199,903 | 5 | Universal Pictures International (UPI) | false | false |
| 9 | 10 | Monsters vs. Aliens | $1,088 | -32.9% | 3 | +2 | $362 | $832,000 | 11 | Paramount Pictures International | false | false |
| 10 | 9 | Dark Planet: Rebellion | $532 | -74.7% | 7 | -12 | $76 | $617,179 | 6 | Gemini Films | false | false |
