| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Angels & Demons | $9,859 | -56.1% | 4 | - | $2,464 | $120,003 | 3 | Sony Pictures Releasing | false | false |
| 2 | 2 | Night at the Museum: Battle of the Smithsonian | $7,713 | -57.1% | 5 | - | $1,542 | $32,756 | 2 | 20th Century Fox International | false | false |
| 3 | - | Ghosts of Girlfriends Past | $7,258 | - | 3 | - | $2,419 | $7,258 | 1 | Warner Bros. | true | false |
| 4 | - | State of Play | $3,225 | - | 1 | - | $3,225 | $3,225 | 1 | United International Pictures | true | false |
| 5 | 3 | Coraline | $2,151 | -65.8% | 1 | - | $2,151 | $23,927 | 3 | United International Pictures | false | false |
| 6 | 4 | The Last House on the Left | $1,661 | -73.2% | 2 | - | $830 | $11,235 | 2 | United International Pictures | false | false |
| 7 | 6 | 17 Again | $1,450 | -51.3% | 2 | - | $725 | $48,047 | 6 | Warner Bros. | false | false |
| 8 | 5 | Star Trek | $1,362 | -64.7% | 2 | -1 | $681 | $39,357 | 4 | United International Pictures | false | false |
| 9 | 7 | X-Men Origins: Wolverine | $988 | -58.4% | 3 | +1 | $329 | $42,228 | 5 | 20th Century Fox International | false | false |
| 10 | 10 | I Love You, Man | $553 | -55.4% | 3 | +1 | $184 | $22,986 | 6 | United International Pictures | false | false |
| 11 | 8 | Observe and Report | $364 | -73.6% | 2 | - | $182 | $15,331 | 4 | Warner Bros. | false | false |
