| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Angels & Demons | $38,784 | -53.1% | 10 | - | $3,878 | $137,985 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Night at the Museum: Battle of the Smithsonian | $17,631 | - | 11 | - | $1,602 | $20,070 | 1 | 20th Century Fox International | true | false |
| 3 | - | My Bloody Valentine | $13,440 | - | 4 | - | $3,360 | $15,393 | 1 | N/A | true | false |
| 4 | 4 | Star Trek | $5,956 | -35.2% | 5 | - | $1,191 | $58,570 | 3 | United International Pictures | false | false |
| 5 | - | Beverly Hills Chihuahua | $5,676 | - | 6 | - | $946 | $7,036 | 1 | Walt Disney Pictures | true | false |
| 6 | 2 | 17 Again | $5,667 | -48.4% | 6 | - | $944 | $71,720 | 4 | Warner Bros. | false | false |
| 7 | 3 | Coraline | $5,526 | -39.9% | 9 | - | $614 | $20,193 | 2 | United International Pictures | false | false |
| 8 | 5 | I Love You, Man | $4,616 | -45.8% | 9 | - | $512 | $125,462 | 5 | United International Pictures | false | false |
| 9 | 6 | Duplicity | $3,476 | -48.2% | 8 | - | $434 | $56,839 | 4 | United International Pictures | false | false |
| 10 | 9 | Taxi 4 | $2,616 | -24.4% | 2 | - | $1,308 | $13,253 | 3 | N/A | false | false |
| 11 | 7 | X-Men Origins: Wolverine | $2,390 | -54.7% | 8 | - | $298 | $65,576 | 4 | 20th Century Fox International | false | false |
| 12 | 10 | Gran Torino | $2,046 | -19.5% | 5 | - | $409 | $81,382 | 7 | Warner Bros. | false | false |
| 13 | 8 | Fast & Furious | $1,063 | -72.8% | 9 | - | $118 | $328,282 | 7 | United International Pictures | false | false |
| 14 | 11 | Monsters vs. Aliens | $992 | -57.7% | 13 | - | $76 | $218,376 | 8 | United International Pictures | false | false |
