| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Night at the Museum: Battle of the Smithsonian | $490,514 | - | 165 | - | $2,972 | $490,514 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Angels & Demons | $449,625 | -29.2% | 110 | - | $4,087 | $1,364,300 | 2 | Sony Pictures Releasing | false | false |
| 3 | 2 | X-Men Origins: Wolverine | $84,539 | -46.7% | 88 | -5 | $960 | $1,386,269 | 4 | 20th Century Fox International | false | false |
| 4 | 3 | Hannah Montana: The Movie | $46,689 | -45.3% | 48 | -2 | $972 | $441,834 | 4 | Walt Disney Pictures | false | false |
| 5 | 4 | The Unborn | $36,235 | -46.4% | 36 | -3 | $1,006 | $246,661 | 3 | United International Pictures | false | false |
| 6 | - | The Strangers | $32,231 | - | 33 | - | $976 | $32,231 | 1 | Cine Colombia | true | false |
| 7 | 5 | Star Trek | $26,978 | -54.8% | 40 | -22 | $674 | $226,010 | 3 | United International Pictures | false | false |
| 8 | 6 | Monsters vs. Aliens | $18,622 | -60% | 5 | -56 | $3,724 | $1,932,840 | 8 | United International Pictures | false | false |
| 9 | - | Venus 2009 Re-release | $9,285 | - | 5 | - | $1,857 | $9,285 | 1 | Cine Colombia | true | false |
| 10 | - | Revolver 2007 Re-release | $6,949 | - | 19 | - | $365 | $6,949 | 1 | Cine Colombia | true | false |
| 11 | 7 | Paul Blart: Mall Cop | $6,726 | -81.9% | 20 | -22 | $336 | $129,748 | 3 | Sony Pictures Releasing | false | false |
| 12 | 10 | Earth | $6,371 | -60.3% | 16 | -5 | $398 | $201,715 | 5 | Walt Disney Pictures | false | false |
| 13 | - | Frozen River | $6,370 | - | 3 | - | $2,123 | $6,370 | 1 | Sony Pictures Releasing | true | false |
| 14 | 9 | Knowing | $2,457 | -86.3% | 5 | -21 | $491 | $624,613 | 6 | Cine Colombia | false | false |
| 15 | 11 | Race to Witch Mountain | $1,366 | -85.8% | 19 | -32 | $71 | $1,322,149 | 9 | Walt Disney Pictures | false | false |
| 16 | 12 | Milk | $1,348 | -80.2% | 3 | -7 | $449 | $101,507 | 5 | United International Pictures | false | false |
| 17 | 8 | Bangkok Dangerous | $954 | -97.3% | 11 | -39 | $86 | $49,552 | 11 | Cine Colombia | false | false |
| 18 | 17 | Rachel Getting Married | $866 | +421.7% | 3 | +2 | $288 | $28,073 | 12 | Sony Pictures Releasing | false | false |
| 19 | - | My Brother is an Only Child | $202 | - | 1 | - | $202 | $202 | 1 | Cine Colombia | true | false |
