| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Angels & Demons | $500,108 | -16.9% | 73 | - | $6,850 | $1,303,175 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Night at the Museum: Battle of the Smithsonian | $497,054 | - | 67 | - | $7,418 | $497,054 | 1 | 20th Century Fox International | true | false |
| 3 | - | Knowing | $154,803 | - | 28 | - | $5,528 | $155,765 | 1 | N/A | true | false |
| 4 | 2 | Hannah Montana: The Movie | $124,551 | -4.7% | 37 | -3 | $3,366 | $900,591 | 4 | Walt Disney Pictures | false | false |
| 5 | 3 | X-Men Origins: Wolverine | $62,674 | -35.4% | 38 | -19 | $1,649 | $926,829 | 4 | 20th Century Fox International | false | false |
| 6 | 4 | Fast & Furious | $43,276 | -41.4% | 24 | -8 | $1,803 | $285,313 | 3 | United International Pictures | false | false |
| 7 | 5 | Star Trek | $29,543 | -53.3% | 16 | -14 | $1,846 | $221,074 | 3 | United International Pictures | false | false |
| 8 | 6 | Earth | $22,378 | -43.1% | 12 | -7 | $1,864 | $323,659 | 5 | Walt Disney Pictures | false | false |
| 9 | 7 | Ghosts of Girlfriends Past | $19,472 | -43.6% | 13 | -4 | $1,497 | $66,139 | 2 | Warner Bros. | false | false |
| 10 | 8 | Vicky Cristina Barcelona | $14,858 | -47.5% | 4 | -9 | $3,714 | $185,631 | 4 | N/A | false | false |
| 11 | 9 | Monsters vs. Aliens | $11,526 | -56.4% | 8 | -9 | $1,440 | $996,482 | 8 | United International Pictures | false | false |
| 12 | 12 | Paris | $8,149 | -41.8% | 5 | - | $1,629 | $43,825 | 3 | N/A | false | false |
| 13 | 10 | Race to Witch Mountain | $4,325 | -83.4% | 7 | -17 | $617 | $665,777 | 7 | Walt Disney Pictures | false | false |
| 14 | 13 | 17 Again | $1,248 | -79.6% | 2 | -6 | $624 | $133,583 | 5 | Warner Bros. | false | false |
