| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Angels & Demons | $635,347 | - | 110 | - | $5,775 | $635,347 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | X-Men Origins: Wolverine | $158,737 | -29.7% | 93 | -19 | $1,706 | $1,259,202 | 3 | 20th Century Fox International | false | false |
| 3 | 4 | Hannah Montana: The Movie | $85,342 | +15.9% | 50 | +2 | $1,706 | $383,847 | 3 | Walt Disney Pictures | false | false |
| 4 | 3 | The Unborn | $67,636 | -18.6% | 39 | +3 | $1,734 | $186,816 | 2 | United International Pictures | false | false |
| 5 | 2 | Star Trek | $59,704 | -33.4% | 62 | -8 | $962 | $182,749 | 2 | United International Pictures | false | false |
| 6 | 6 | Monsters vs. Aliens | $46,514 | -5.4% | 61 | -15 | $762 | $1,908,316 | 7 | United International Pictures | false | false |
| 7 | 5 | Paul Blart: Mall Cop | $37,068 | -40.8% | 42 | -8 | $882 | $115,275 | 2 | Sony Pictures Releasing | false | false |
| 8 | - | Bangkok Dangerous | $35,093 | - | 50 | - | $701 | $35,093 | 10 | Cine Colombia | false | false |
| 9 | 7 | Knowing | $17,911 | -62.9% | 26 | -12 | $688 | $615,874 | 5 | Cine Colombia | false | false |
| 10 | 10 | Earth | $16,066 | -5.1% | 21 | +4 | $765 | $192,923 | 4 | Walt Disney Pictures | false | false |
| 11 | 8 | Race to Witch Mountain | $9,636 | -55.5% | 51 | -14 | $188 | $1,319,171 | 8 | Walt Disney Pictures | false | false |
| 12 | 11 | Milk | $6,812 | -33.4% | 10 | -7 | $681 | $97,325 | 4 | United International Pictures | false | false |
| 13 | 9 | Fast & Furious | $6,534 | -69.2% | 18 | -25 | $363 | $885,350 | 7 | United International Pictures | false | false |
| 14 | 13 | I Served the King of England | $2,118 | -38.2% | 1 | -3 | $2,118 | $26,634 | 4 | Cine Colombia | false | false |
| 15 | 12 | The Pink Panther 2 | $1,041 | -77.7% | 4 | -19 | $260 | $184,294 | 5 | Sony Pictures Releasing | false | false |
| 16 | 14 | Inkheart | $450 | -72.4% | 4 | -8 | $112 | $327,602 | 7 | Cine Colombia | false | false |
| 17 | 20 | Rachel Getting Married | $166 | -40.5% | 1 | - | $166 | $27,037 | 11 | Sony Pictures Releasing | false | false |
