| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | X-Men Origins: Wolverine | $338,374 | -53.2% | 60 | -12 | $5,639 | $1,515,884 | 2 | 20th Century Fox International | false | false |
| 2 | 2 | Race to Witch Mountain | $227,447 | -41.9% | 40 | - | $5,686 | $879,783 | 2 | Walt Disney Pictures | false | false |
| 3 | - | Star Trek | $165,821 | - | 45 | - | $3,684 | $165,821 | 1 | United International Pictures | true | false |
| 4 | 3 | Fast & Furious | $135,062 | -51.9% | 49 | +1 | $2,756 | $4,231,744 | 6 | United International Pictures | false | false |
| 5 | - | Coraline | $134,549 | - | 37 | - | $3,636 | $134,549 | 1 | United International Pictures | true | false |
| 6 | 5 | He's Just Not That Into You | $75,290 | -38.4% | 25 | -2 | $3,011 | $292,613 | 2 | N/A | false | false |
| 7 | 6 | The Strangers | $41,890 | -54.7% | 14 | -6 | $2,992 | $375,048 | 3 | N/A | false | false |
| 8 | 7 | Earth | $38,657 | -46.6% | 10 | - | $3,865 | $259,337 | 3 | Walt Disney Pictures | false | false |
| 9 | 4 | Monsters vs. Aliens | $36,573 | -81.3% | 48 | -9 | $761 | $2,999,125 | 6 | United International Pictures | false | false |
| 10 | - | Milk | $27,029 | - | 18 | - | $1,501 | $42,822 | 1 | United International Pictures | true | false |
| 11 | 8 | Slumdog Millionaire | $24,398 | -62.2% | 16 | -5 | $1,524 | $1,694,874 | 11 | N/A | false | false |
| 12 | 12 | Inkheart | $17,743 | -47.2% | 18 | -2 | $985 | $910,144 | 7 | N/A | false | false |
| 13 | 9 | Role Models | $15,408 | -75.5% | 12 | -15 | $1,284 | $263,652 | 3 | United International Pictures | false | false |
| 14 | 11 | Paul Blart: Mall Cop | $13,623 | -60.1% | 9 | -4 | $1,513 | $1,298,454 | 9 | Sony Pictures Releasing | false | false |
| 15 | 10 | Catacombs | $13,004 | -64.3% | 11 | -2 | $1,182 | $158,800 | 3 | N/A | false | false |
| 16 | 14 | Balls of Fury | $12,178 | -48.2% | 8 | -1 | $1,522 | $197,854 | 4 | N/A | false | false |
| 17 | 16 | Swing con son | $8,263 | -46.3% | 9 | - | $918 | $47,363 | 3 | N/A | false | false |
| 18 | 21 | Pride and Glory | $4,715 | -5.5% | 7 | +4 | $673 | $155,860 | 4 | N/A | false | false |
| 19 | 15 | Underworld: Rise of the Lycans | $4,538 | -74.8% | 7 | -6 | $648 | $1,023,785 | 7 | Sony Pictures Releasing | false | false |
| 20 | 13 | Dragonball Evolution | $4,210 | -87.1% | 15 | -14 | $280 | $1,140,449 | 5 | 20th Century Fox International | false | false |
| 21 | 18 | The Band's Visit | $3,916 | -58.7% | 4 | +1 | $979 | $15,489 | 2 | N/A | false | false |
| 22 | 17 | Confessions of a Shopaholic | $2,294 | -83.3% | 6 | -4 | $382 | $959,194 | 7 | Walt Disney Pictures | false | false |
| 23 | 20 | Sex Drive | $1,672 | -74.8% | 5 | -5 | $334 | $188,015 | 4 | N/A | false | false |
| 24 | 23 | Captivity | $866 | -71% | 3 | -2 | $288 | $296,357 | 7 | N/A | false | false |
| 25 | 25 | The International | $133 | -87.9% | 1 | -1 | $133 | $573,580 | 10 | Sony Pictures Releasing | false | false |
| 26 | 19 | Chaos | $61 | -99.2% | 1 | -4 | $61 | $218,145 | 5 | - | false | false |
