| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | X-Men Origins: Wolverine | $783,775 | - | 103 | - | $7,609 | $1,147,501 | 1 | Warner Bros. | true | false |
| 2 | 1 | 17 Again | $294,681 | -4.2% | 70 | - | $4,209 | $922,161 | 2 | RCV Film Distribution | false | false |
| 3 | 3 | He's Just Not That Into You | $193,199 | -17% | 86 | - | $2,246 | $1,088,109 | 3 | Paradiso Entertainment | false | false |
| 4 | 2 | Fast & Furious | $173,115 | -30.9% | 96 | -2 | $1,803 | $3,295,652 | 5 | Universal Pictures International (UPI) | false | false |
| 5 | 4 | Knowing | $150,409 | -14.9% | 57 | - | $2,638 | $1,113,432 | 4 | Independent Films | false | false |
| 6 | 6 | Monsters vs. Aliens | $141,701 | +26.2% | 126 | +4 | $1,124 | $1,449,718 | 5 | Universal Pictures International (UPI) | false | false |
| 7 | 5 | The Reader | $114,933 | -11.1% | 35 | - | $3,283 | $1,131,575 | 5 | Benelux Film Distributors | false | false |
| 8 | 8 | Slumdog Millionaire | $88,343 | +8.1% | 46 | - | $1,920 | $4,512,233 | 12 | Cinéart | false | false |
| 9 | 9 | Beverly Hills Chihuahua | $83,665 | +67.6% | 58 | - | $1,442 | $305,911 | 2 | Walt Disney Pictures | false | false |
| 10 | - | The Haunting in Connecticut | $78,799 | - | 22 | - | $3,581 | $87,077 | 1 | Benelux Film Distributors | true | false |
| 11 | 7 | The International | $62,084 | -28.3% | 40 | - | $1,552 | $358,104 | 3 | Sony Pictures Releasing | false | false |
| 12 | 12 | Lemo | $50,885 | +22.2% | 106 | - | $480 | $408,047 | 4 | Independent Films | false | false |
| 13 | 11 | Bride Wars | $32,305 | -31.4% | 59 | -13 | $547 | $1,432,228 | 6 | Warner Bros. | false | false |
| 14 | 10 | The Uninvited | $28,527 | -41.7% | 27 | -6 | $1,056 | $198,929 | 3 | Universal Pictures International (UPI) | false | false |
| 15 | 15 | My Bloody Valentine | $24,684 | -25.3% | 18 | -1 | $1,371 | $1,118,635 | 8 | RCV Film Distribution | false | false |
| 16 | 18 | Inkheart | $22,031 | -5.8% | 40 | +2 | $550 | $97,770 | 3 | Paradiso Entertainment | false | false |
| 17 | 19 | Mammoth | $19,801 | -1.4% | 16 | - | $1,237 | $56,843 | 2 | A-Film Distribution | false | false |
| 18 | 20 | My Dad's a Detective | $19,059 | +47.5% | 41 | -2 | $464 | $132,105 | 4 | RCV Film Distribution | false | false |
| 19 | 13 | The Boat That Rocked | $18,380 | -49.5% | 34 | -37 | $540 | $166,101 | 3 | Universal Pictures International (UPI) | false | false |
| 20 | 14 | Dragonball Evolution | $18,309 | -46.5% | 56 | -4 | $326 | $382,916 | 4 | Warner Bros. | false | false |
