| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | 17 Again | $163,119 | -37.3% | 56 | +1 | $2,912 | $552,001 | 2 | NuMetro Distribution | false | false |
| 2 | 2 | Fast & Furious | $158,268 | -23.3% | 63 | - | $2,512 | $1,277,820 | 3 | United International Pictures | false | false |
| 3 | 3 | Monsters vs. Aliens | $95,011 | -3% | 78 | -7 | $1,218 | $1,130,595 | 4 | United International Pictures | false | false |
| 4 | - | I Love You, Man | $75,941 | - | 50 | - | $1,518 | $75,941 | 1 | United International Pictures | true | false |
| 5 | 5 | Hotel for Dogs | $62,607 | +18.9% | 43 | - | $1,455 | $157,724 | 2 | United International Pictures | false | false |
| 6 | 4 | Marley & Me | $57,539 | +2.8% | 65 | - | $885 | $1,239,728 | 6 | NuMetro Distribution | false | false |
| 7 | - | The International | $53,938 | - | 19 | - | $2,838 | $53,938 | 1 | Ster-Kinekor Pictures | true | false |
| 8 | 6 | Slumdog Millionaire | $37,513 | -0.9% | 20 | - | $1,875 | $941,476 | 8 | Ster-Kinekor Pictures | false | false |
| 9 | 8 | Race to Witch Mountain | $30,200 | +10.6% | 40 | -10 | $755 | $497,567 | 5 | Ster-Kinekor Pictures | false | false |
| 10 | - | Milk | $30,140 | - | 10 | - | $3,014 | $30,140 | 1 | Ster-Kinekor Pictures | true | false |
| 11 | 7 | Dragonball Evolution | $29,846 | -4.3% | 35 | - | $852 | $244,032 | 3 | 20th Century Fox International | false | false |
| 12 | 9 | Confessions of a Shopaholic | $19,817 | -22.5% | 32 | -11 | $619 | $661,069 | 7 | Ster-Kinekor Pictures | false | false |
| 13 | 10 | The Reader | $18,334 | -8.1% | 10 | - | $1,833 | $200,001 | 5 | Ster-Kinekor Pictures | false | false |
| 14 | 12 | Tornado 2009 Re-release | $15,658 | -7.5% | 17 | -16 | $921 | $110,152 | 3 | Ster-Kinekor Pictures | false | false |
| 15 | 11 | Gran Torino | $14,406 | -15.4% | 23 | - | $626 | $227,879 | 5 | NuMetro Distribution | false | false |
| 16 | 13 | Underworld: Rise of the Lycans | $14,210 | +2.6% | 22 | -4 | $645 | $262,809 | 5 | Ster-Kinekor Pictures | false | false |
| 17 | 14 | 12 Rounds | $9,572 | -13.4% | 23 | -1 | $416 | $127,089 | 4 | NuMetro Distribution | false | false |
| 18 | 15 | He's Just Not That Into You | $7,194 | -30.9% | 17 | -10 | $423 | $931,784 | 11 | NuMetro Distribution | false | false |
| 19 | 16 | The Curious Case of Benjamin Button | $6,189 | -23.5% | 15 | -3 | $412 | $664,574 | 9 | NuMetro Distribution | false | false |
| 20 | 19 | Defiance | $4,265 | -7.9% | 5 | -2 | $853 | $66,164 | 6 | United International Pictures | false | false |
| 21 | 20 | 8 x 10 Tasveer | $4,012 | -0.9% | 4 | - | $1,003 | $10,948 | 2 | NuMetro Distribution | false | false |
| 22 | 22 | Friday the 13th | $2,916 | +12.9% | 6 | +1 | $486 | $78,023 | 7 | United International Pictures | false | false |
| 23 | 21 | Watchmen | $2,483 | -10.3% | 6 | -1 | $413 | $437,472 | 8 | Ster-Kinekor Pictures | false | false |
| 24 | 23 | The Baader Meinhof Complex | $1,685 | -33.6% | 4 | -1 | $421 | $21,782 | 4 | United International Pictures | false | false |
