| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Race to Witch Mountain | $101,432 | -18.9% | 36 | - | $2,817 | $450,221 | 3 | Walt Disney Pictures | false | false |
| 2 | 2 | Monsters vs. Aliens | $94,946 | -23.8% | 54 | -7 | $1,758 | $7,946,815 | 4 | United International Pictures | false | false |
| 3 | - | Earth | $86,123 | - | 19 | - | $4,532 | $93,913 | 1 | Walt Disney Pictures | true | false |
| 4 | 3 | The Unborn | $66,930 | -11.9% | 29 | +2 | $2,307 | $167,028 | 2 | United International Pictures | false | false |
| 5 | - | 17 Again | $48,988 | - | 22 | - | $2,226 | $48,988 | 1 | Warner Bros. | true | false |
| 6 | - | Paul Blart: Mall Cop | $37,767 | - | 25 | - | $1,510 | $37,767 | 1 | Sony Pictures Releasing | true | false |
| 7 | - | The Wrestler | $33,257 | - | 14 | - | $2,375 | $33,257 | 1 | N/A | true | false |
| 8 | 4 | Dragonball Evolution | $30,391 | -55.4% | 41 | -13 | $741 | $335,033 | 3 | 20th Century Fox International | false | false |
| 9 | 5 | Gran Torino | $27,831 | +5.1% | 10 | -1 | $2,783 | $295,858 | 6 | Warner Bros. | false | false |
| 10 | 6 | Slumdog Millionaire | $20,032 | -18.6% | 14 | -3 | $1,430 | $723,607 | 10 | Bazuca Films | false | false |
| 11 | 7 | Death Sentence | $9,434 | -52.4% | 16 | +2 | $589 | $34,842 | 2 | N/A | false | false |
| 12 | 9 | Changeling | $9,011 | -23.5% | 7 | -3 | $1,287 | $259,051 | 7 | United International Pictures | false | false |
| 13 | 8 | Underworld: Rise of the Lycans | $6,409 | -62.2% | 14 | -13 | $457 | $313,492 | 6 | Sony Pictures Releasing | false | false |
| 14 | 11 | Confessions of a Shopaholic | $6,146 | -28.2% | 10 | +2 | $614 | $105,093 | 5 | Walt Disney Pictures | false | false |
| 15 | 12 | He's Just Not That Into You | $4,591 | -41% | 3 | - | $1,530 | $279,930 | 11 | Warner Bros. | false | false |
| 16 | 10 | Bedtime Stories | $4,296 | -52% | 8 | -12 | $537 | $1,030,262 | 10 | Walt Disney Pictures | false | false |
| 17 | 13 | Reincarnation 2009 Re-release | $3,176 | -37.9% | 6 | - | $529 | $66,945 | 5 | Andes Films | false | false |
| 18 | 18 | Doubt | $2,926 | +24.7% | 2 | - | $1,463 | $133,548 | 9 | Walt Disney Pictures | false | false |
| 19 | 17 | My Brother is an Only Child | $2,631 | -25% | 1 | - | $2,631 | $10,425 | 3 | Transeuropa | false | false |
| 20 | 16 | Alpha Dog | $2,084 | -49.3% | 5 | - | $416 | $7,664 | 2 | Andes Films | false | false |
| 21 | 15 | Milk | $1,101 | -75.7% | 2 | -2 | $550 | $41,028 | 5 | United International Pictures | false | false |
| 22 | 14 | Sex Drive | $572 | -88.1% | 5 | -8 | $114 | $24,700 | 3 | N/A | false | false |
| 23 | 21 | Valkyrie | $302 | -69.4% | 1 | -1 | $302 | $788,657 | 11 | 20th Century Fox International | false | false |
