| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Monsters vs. Aliens | $3,043,307 | -26.7% | 517 | -3 | $5,886 | $25,655,644 | 3 | Paramount Pictures International | false | false |
| 2 | 1 | Fast & Furious | $2,853,659 | -60.6% | 385 | +21 | $7,412 | $15,154,014 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | 3 | 17 Again | $2,622,415 | -30.3% | 410 | +3 | $6,396 | $11,218,338 | 2 | Entertainment Film Distributors | false | false |
| 4 | - | I Love You, Man | $1,660,071 | - | 336 | - | $4,940 | $1,660,071 | 1 | Paramount Pictures International | true | false |
| 5 | - | Crank: High Voltage | $820,326 | - | 319 | - | $2,571 | $820,326 | 1 | Lionsgate Films | true | false |
| 6 | 4 | The Boat That Rocked | $737,893 | -47.9% | 439 | -21 | $1,680 | $7,847,693 | 3 | Universal Pictures International (UPI) | false | false |
| 7 | 6 | Race to Witch Mountain | $693,806 | -18.7% | 412 | +3 | $1,683 | $2,812,094 | 2 | Walt Disney Pictures | false | false |
| 8 | - | In the Loop | $693,688 | - | 104 | - | $6,670 | $693,688 | 1 | Optimum Releasing | true | false |
| 9 | 5 | Knowing | $462,287 | -49.2% | 302 | -71 | $1,530 | $9,427,778 | 4 | Entertainment One | false | false |
| 10 | 7 | Marley & Me | $450,325 | -34.8% | 374 | -28 | $1,204 | $22,059,327 | 6 | 20th Century Fox International | false | false |
| 11 | 9 | The Haunting in Connecticut | $289,827 | -48.1% | 251 | -30 | $1,154 | $5,841,171 | 4 | Entertainment Film Distributors | false | false |
| 12 | 11 | Let the Right One In | $225,792 | -31.4% | 95 | +27 | $2,376 | $835,679 | 2 | Momentum Pictures | false | false |
| 13 | 10 | Paul Blart: Mall Cop | $200,932 | -41.5% | 290 | -51 | $692 | $7,747,205 | 5 | Sony Pictures Releasing | false | false |
| 14 | 8 | Dragonball Evolution | $104,093 | -83.7% | 308 | -11 | $337 | $959,034 | 2 | 20th Century Fox International | false | false |
| 15 | 13 | Gran Torino | $95,811 | -39.8% | 87 | -32 | $1,101 | $12,045,695 | 9 | Warner Bros. | false | false |
| 16 | 12 | The Damned United | $92,345 | -56.6% | 130 | -46 | $710 | $2,948,416 | 4 | Sony Pictures Releasing | false | false |
| 17 | 14 | Fifty Dead Men Walking | $83,369 | -42.9% | 80 | +4 | $1,042 | $379,838 | 2 | - | false | false |
| 18 | 18 | Hotel for Dogs | $60,338 | +2.8% | 116 | -46 | $520 | $10,425,759 | 10 | Paramount Pictures International | false | false |
| 19 | 15 | Duplicity | $58,883 | -58.9% | 59 | -33 | $998 | $4,174,290 | 5 | Universal Pictures International (UPI) | false | false |
| 20 | 19 | The Young Victoria | $44,492 | -2.9% | 49 | - | $908 | $7,059,915 | 7 | Momentum Pictures | false | false |
| 21 | 16 | Slumdog Millionaire | $43,804 | -47.1% | 36 | -19 | $1,216 | $46,623,635 | 15 | Pathé | false | false |
| 22 | 17 | Watchmen | $42,128 | -46% | 37 | -13 | $1,138 | $13,080,019 | 7 | Paramount Pictures International | false | false |
| 23 | - | Good | $40,019 | - | 14 | - | $2,858 | $40,019 | 1 | Lionsgate Films | true | false |
| 24 | - | Mini Punjab | $23,422 | - | 8 | - | $2,927 | $23,422 | 1 | - | true | false |
| 25 | 20 | The Class | $18,524 | -44.5% | 14 | -2 | $1,323 | $1,205,420 | 8 | Artificial Eye | false | false |
| 26 | 21 | Bolt | $18,322 | -39% | 59 | -38 | $310 | $26,512,455 | 10 | Walt Disney Pictures | false | false |
| 27 | 29 | Madagascar: Escape 2 Africa | $17,912 | -6% | 76 | -1 | $235 | $34,382,974 | 20 | Paramount Pictures International | false | false |
| 28 | - | Not Easily Broken | $15,868 | - | 64 | - | $247 | $15,868 | 1 | Sony Pictures Releasing | true | false |
| 29 | 23 | The 400 Blows 2009 Re-release | $14,856 | -47.8% | 10 | +1 | $1,485 | $69,416 | 2 | British Film Institute (BFI) | false | false |
| 30 | 33 | Waveriders | $14,067 | +8.5% | 13 | -1 | $1,082 | $116,798 | 3 | Element Films | false | false |
| 31 | 22 | Il Divo | $13,683 | -54.4% | 10 | -2 | $1,368 | $461,299 | 5 | Artificial Eye | false | false |
| 32 | 26 | Tera Mera Ki Rishta | $12,106 | -40.8% | 8 | - | $1,513 | $60,815 | 2 | Eros Worldwide | false | false |
| 33 | 31 | A Summer in Genoa | $11,455 | -32.8% | 10 | +1 | $1,145 | $156,981 | 4 | - | false | false |
| 34 | 27 | Two Lovers | $8,855 | -56.2% | 7 | -9 | $1,265 | $377,060 | 4 | Lionsgate Films | false | false |
| 35 | 32 | Under the Sea 3D | $8,421 | -44.7% | 1 | - | $8,421 | $246,204 | 10 | IMAX | false | false |
| 36 | 24 | 8 x 10 Tasveer | $7,902 | -68.6% | 8 | -3 | $987 | $147,035 | 3 | - | false | false |
| 37 | 28 | The Reader | $7,726 | -59.8% | 9 | -6 | $858 | $8,503,145 | 16 | Entertainment Film Distributors | false | false |
| 38 | - | I Saw the Sun 2009 Re-release | $7,020 | - | 1 | - | $7,020 | $7,020 | 1 | N/A | true | false |
| 39 | 40 | Milk | $5,778 | -32.4% | 5 | +1 | $1,155 | $2,099,138 | 13 | Momentum Pictures | false | false |
| 40 | 35 | Vicky Cristina Barcelona | $5,679 | -51.2% | 4 | -5 | $1,419 | $3,882,616 | 11 | Optimum Releasing | false | false |
| 41 | 37 | Tony Manero | $4,812 | -56.5% | 7 | - | $687 | $26,119 | 2 | - | false | false |
| 42 | 25 | The Secret of Moonacre | $4,556 | -77.8% | 17 | -63 | $268 | $1,352,677 | 11 | Warner Bros. | false | false |
| 43 | 41 | He's Just Not That Into You | $4,315 | -42.2% | 3 | -2 | $1,438 | $14,014,800 | 11 | Entertainment Film Distributors | false | false |
| 44 | 45 | Revolutionary Road | $3,941 | -26.8% | 10 | +5 | $394 | $5,119,079 | 12 | Paramount Pictures International | false | false |
| 45 | 43 | My Bloody Valentine | $3,707 | -41.2% | 13 | -4 | $285 | $10,209,454 | 14 | Lionsgate Films | false | false |
| 46 | 38 | Bronson | $3,386 | -69% | 10 | -11 | $338 | $1,316,902 | 6 | Vertigo Films | false | false |
| 47 | 30 | Ayan | $3,149 | -83.1% | 2 | -9 | $1,574 | $116,900 | 3 | Ayngaran International | false | false |
| 48 | 34 | Religulous | $2,781 | -76.5% | 5 | -3 | $556 | $77,226 | 3 | Momentum Pictures | false | false |
| 49 | 36 | The Tale of Despereaux | $2,407 | -79.3% | 14 | -57 | $171 | $3,747,942 | 18 | Universal Pictures International (UPI) | false | false |
| 50 | 42 | Modern Life | $2,395 | -64.4% | 4 | - | $598 | $32,537 | 3 | Soda Pictures | false | false |
| 51 | 44 | Confessions of a Shopaholic | $2,356 | -60% | 7 | -12 | $336 | $12,204,306 | 9 | Walt Disney Pictures | false | false |
| 52 | 46 | Anvil | $2,294 | -35.1% | 6 | +2 | $382 | $218,835 | 9 | The Works UK Distribution | false | false |
| 53 | 59 | The Wrestler | $1,935 | +101.6% | 4 | +3 | $483 | $3,753,364 | 14 | Optimum Releasing | false | false |
| 54 | 68 | Frost/Nixon | $1,802 | +1,649.5% | 3 | +2 | $600 | $2,799,089 | 13 | Universal Pictures International (UPI) | false | false |
| 55 | 51 | Doubt | $1,620 | -27.3% | 4 | -2 | $405 | $1,915,668 | 11 | Walt Disney Pictures | false | false |
| 56 | 63 | The Curious Case of Benjamin Button | $1,535 | +117.7% | 6 | +4 | $255 | $13,420,964 | 11 | Warner Bros. | false | false |
| 57 | - | Before I Forget | $1,204 | - | 1 | - | $1,204 | $1,204 | 1 | Peccadillo Pictures | true | false |
| 58 | - | In Search of Beethoven | $1,167 | - | 1 | - | $1,167 | $1,167 | 1 | Seventh Art Productions | true | false |
| 59 | 39 | Vampire Killers | $1,160 | -88.6% | 11 | -38 | $105 | $2,475,321 | 5 | Momentum Pictures | false | false |
| 60 | 50 | The Age of Stupid | $1,111 | -55.1% | 2 | -1 | $555 | $244,766 | 5 | Periscoop Film | false | false |
| 61 | 52 | Wendy and Lucy | $930 | -55.8% | 3 | -1 | $310 | $143,599 | 7 | Soda Pictures | false | false |
| 62 | 60 | Flame & Citron | $605 | -33.4% | 2 | +1 | $302 | $59,997 | 7 | - | false | false |
| 63 | 55 | The Burning Plain | $572 | -49.4% | 1 | -1 | $572 | $17,706 | 6 | Paramount Pictures International | false | false |
| 64 | 47 | Che: Part Two | $522 | -83.3% | 3 | -4 | $174 | $417,005 | 9 | Optimum Releasing | false | false |
| 65 | 64 | The Secret of Kells | $519 | -25.2% | 6 | - | $86 | $95,869 | 7 | Walt Disney Pictures | false | false |
| 66 | 58 | Cherry Blossoms | $422 | -57.2% | 1 | - | $422 | $5,688 | 3 | Periscoop Film | false | false |
| 67 | - | The Unborn | $379 | - | 2 | - | $189 | $5,574,004 | 8 | Universal Pictures International (UPI) | false | false |
| 68 | 48 | Che: Part One | $352 | -88.4% | 2 | -5 | $176 | $1,976,871 | 16 | Optimum Releasing | false | false |
| 69 | 65 | Afghan Star | $246 | -61.1% | 1 | - | $246 | $10,794 | 4 | - | false | false |
| 70 | 49 | Bottle Shock | $222 | -91.8% | 1 | -3 | $222 | $13,473 | 5 | Paramount Pictures International | false | false |
| 71 | 54 | In the City of Sylvia | $214 | -88.8% | 2 | -3 | $107 | $87,611 | 6 | Axiom Films | false | false |
| 72 | 66 | Twilight | $167 | -70.9% | 3 | -2 | $55 | $16,411,883 | 18 | Contender Entertainment Group | false | false |
| 73 | 53 | Traitor | $80 | -96.2% | 1 | -6 | $80 | $237,373 | 4 | Momentum Pictures | false | false |
| 74 | 61 | Waltz with Bashir | $30 | -96.6% | 1 | - | $30 | $1,038,720 | 22 | Artificial Eye | false | false |
