| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 11 | Fast & Furious | $5,767,864 | +3,016.5% | 345 | +312 | $16,718 | $5,956,753 | 2 | Universal Pictures International (UPI) | false | false |
| 2 | 2 | Monsters vs. Aliens | $2,347,727 | +13.8% | 371 | -11 | $6,328 | $11,103,666 | 3 | Paramount Pictures International | false | false |
| 3 | 1 | 17 Again | $1,728,030 | -23.4% | 223 | +1 | $7,749 | $5,855,000 | 2 | Roadshow Films | false | false |
| 4 | 4 | Race to Witch Mountain | $955,857 | +4% | 289 | - | $3,307 | $3,309,985 | 2 | Walt Disney Pictures | false | false |
| 5 | 3 | The Boat That Rocked | $742,510 | -25.5% | 291 | -2 | $2,551 | $2,489,174 | 2 | Universal Pictures International (UPI) | false | false |
| 6 | 5 | Knowing | $359,908 | -46.1% | 202 | -2 | $1,781 | $4,792,765 | 4 | Icon Film Distribution | false | false |
| 7 | 6 | Dragonball Evolution | $330,038 | -50.3% | 192 | - | $1,718 | $1,702,289 | 2 | 20th Century Fox International | false | false |
| 8 | 7 | The Pink Panther 2 | $277,539 | -9% | 188 | -10 | $1,476 | $1,629,198 | 3 | Sony Pictures Releasing | false | false |
| 9 | 10 | Paul Blart: Mall Cop | $171,739 | -19% | 133 | -33 | $1,291 | $3,453,674 | 5 | Sony Pictures Releasing | false | false |
| 10 | 12 | Inkheart | $161,158 | -10.1% | 132 | -3 | $1,220 | $1,028,365 | 3 | Roadshow Films | false | false |
| 11 | 9 | Confessions of a Shopaholic | $154,639 | -31.3% | 122 | -46 | $1,267 | $6,410,257 | 6 | Walt Disney Pictures | false | false |
| 12 | 13 | Mary and Max | $140,166 | -10.2% | 50 | +1 | $2,803 | $411,594 | 2 | Icon Film Distribution | false | false |
| 13 | 8 | Duplicity | $125,782 | -51.8% | 91 | -62 | $1,382 | $3,547,937 | 5 | Universal Pictures International (UPI) | false | false |
| 14 | 15 | Elegy | $108,709 | -13.7% | 22 | - | $4,941 | $354,476 | 2 | Hopscotch Films | false | false |
| 15 | - | The Boy in the Striped Pajamas | $104,820 | - | 103 | - | $1,017 | $104,820 | - | Walt Disney Pictures | - | false |
| 16 | 14 | Easy Virtue | $100,883 | -23.5% | 63 | -5 | $1,601 | $1,598,108 | 6 | Hopscotch Films | false | false |
| 17 | 19 | The Reader | $86,979 | -12.2% | 45 | - | $1,932 | $2,798,210 | 9 | Roadshow Films | false | false |
| 18 | 16 | Slumdog Millionaire | $81,913 | -34.6% | 96 | -20 | $853 | $14,444,015 | 18 | Icon Film Distribution | false | false |
| 19 | 18 | Summer Hours | $77,345 | -24.9% | 25 | +4 | $3,093 | $487,675 | 3 | Palace Films | false | false |
| 20 | 17 | Gran Torino | $71,058 | -37.8% | 78 | -10 | $911 | $11,524,910 | 13 | Roadshow Films | false | false |
| 21 | - | Tulpan | $14,336 | - | 14 | - | $1,024 | $14,336 | - | Palace Films | - | false |
