| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Fast & Furious | $394,286 | -25.4% | 47 | +2 | $8,389 | $1,055,587 | 2 | Universal Pictures International (UPI) | false | false |
| 2 | - | Dragonball Evolution | $270,582 | - | 47 | - | $5,757 | $270,582 | 1 | 20th Century Fox International | true | false |
| 3 | 2 | Esperando la carroza 2: Se acabó la fiesta | $264,901 | -37.2% | 87 | -1 | $3,044 | $777,320 | 2 | Primer Plano Film Group | false | false |
| 4 | - | Race to Witch Mountain | $254,271 | - | 48 | - | $5,297 | $254,271 | 1 | Walt Disney Pictures | true | false |
| 5 | 4 | Knowing | $214,255 | -31.6% | 48 | -1 | $4,463 | $591,912 | 2 | Alfa Films | false | false |
| 6 | 3 | Monsters vs. Aliens | $183,991 | -56.3% | 92 | +1 | $1,999 | $663,600 | 2 | Paramount Pictures International | false | false |
| 7 | 5 | Música en espera | $90,776 | -30.4% | 40 | +2 | $2,269 | $667,320 | 4 | Distribution Company | false | false |
| 8 | 8 | He's Just Not That Into You | $59,750 | -11% | 33 | - | $1,810 | $782,713 | 6 | Distribution Company | false | false |
| 9 | 6 | The International | $52,783 | -26.5% | 30 | - | $1,759 | $255,025 | 3 | Sony Pictures Releasing | false | false |
| 10 | - | The Fish Child | $52,064 | - | 36 | - | $1,446 | $52,064 | 1 | Distribution Company | true | false |
| 11 | 9 | Gran Torino | $43,097 | -34.8% | 49 | -1 | $879 | $834,141 | 6 | Warner Bros. | false | false |
| 12 | 7 | Slumdog Millionaire | $42,822 | -40% | 42 | -1 | $1,019 | $1,446,043 | 9 | Distribution Company | false | false |
| 13 | - | Belle toujours 2008 Re-release | $28,577 | - | 7 | - | $4,082 | $28,577 | 1 | Impacto Cine | true | false |
| 14 | 10 | Confessions of a Shopaholic | $24,505 | -45.6% | 37 | -7 | $662 | $315,015 | 4 | Walt Disney Pictures | false | false |
| 15 | 13 | Rumba | $15,018 | -43.4% | 8 | - | $1,877 | $46,272 | 2 | Distribution Company | false | false |
| 16 | - | Cloud 9 | $14,809 | - | 5 | - | $2,961 | $14,809 | 1 | Primer Plano Film Group | true | false |
| 17 | 11 | Transporter 3 | $12,715 | -57.6% | 34 | -5 | $373 | $370,546 | 5 | - | false | false |
| 18 | 15 | Hotel for Dogs | $12,386 | -48.7% | 41 | - | $302 | $607,364 | 8 | Paramount Pictures International | false | false |
| 19 | 12 | Bedtime Stories | $11,498 | -59.5% | 41 | -3 | $280 | $2,085,218 | 10 | Walt Disney Pictures | false | false |
| 20 | 14 | The Edge of Heaven | $10,703 | -56.6% | 7 | -5 | $1,529 | $128,358 | 4 | Alfa Films | false | false |
| 21 | 16 | Paris | $6,264 | -67.6% | 5 | -6 | $1,252 | $194,249 | 5 | Impacto Cine | false | false |
| 22 | 17 | Gomorrah | $5,430 | -65.9% | 11 | -7 | $493 | $244,641 | 5 | Alfa Films | false | false |
| 23 | 20 | Bonneville | $3,232 | -69.9% | 3 | -8 | $1,077 | $46,445 | 3 | Impacto Cine | false | false |
| 24 | 18 | The Curious Case of Benjamin Button | $3,189 | -76.9% | 14 | -20 | $227 | $2,042,592 | 10 | Warner Bros. | false | false |
| 25 | 26 | Unfair Competition 2009 Re-release | $3,142 | -31.9% | 3 | - | $1,047 | $41,994 | 6 | Primer Plano Film Group | false | false |
| 26 | 24 | Fireflies in the Garden 2008 Re-release | $2,743 | -48.7% | 8 | -3 | $342 | $34,109 | 3 | - | false | false |
| 27 | 23 | Coraline | $2,402 | -64.3% | 9 | -2 | $266 | $129,875 | 5 | Universal Pictures International (UPI) | false | false |
| 28 | 19 | Push | $2,140 | -82.8% | 4 | -11 | $535 | $65,701 | 3 | Alfa Films | false | false |
| 29 | 25 | Mundo alas | $2,079 | -59.7% | 6 | -2 | $346 | $22,285 | 3 | Distribution Company | false | false |
| 30 | 27 | Vicky Cristina Barcelona | $2,050 | -55.5% | 8 | -9 | $256 | $773,326 | 10 | Pachamama Cine | false | false |
| 31 | 22 | Seven Pounds | $1,999 | -71.5% | 5 | -7 | $399 | $260,249 | 7 | Sony Pictures Releasing | false | false |
| 32 | 21 | Bride Wars | $1,780 | -82.3% | 6 | -14 | $296 | $388,272 | 7 | 20th Century Fox International | false | false |
| 33 | 29 | Doubt | $1,447 | +0.1% | 8 | +2 | $180 | $537,146 | 13 | Walt Disney Pictures | false | false |
| 34 | 40 | Changeling | $1,157 | +184.3% | 6 | +3 | $192 | $2,118,746 | 12 | Universal Pictures International (UPI) | false | false |
| 35 | 33 | Bolt | $976 | +3.1% | 7 | - | $139 | $2,118,746 | 13 | Walt Disney Pictures | false | false |
| 36 | 32 | Milk | $917 | -4.8% | 3 | -1 | $305 | $237,724 | 9 | Universal Pictures International (UPI) | false | false |
| 37 | 34 | Watchmen | $658 | -22.4% | 6 | +1 | $109 | $429,682 | 6 | Paramount Pictures International | false | false |
| 38 | 43 | Revolutionary Road | $503 | +127.6% | 4 | +2 | $125 | $290,038 | 11 | Paramount Pictures International | false | false |
| 39 | 35 | The Window | $468 | -39.8% | 1 | -2 | $468 | $32,662 | 5 | Distribution Company | false | false |
| 40 | 36 | The Pink Panther 2 | $466 | -35.5% | 3 | -4 | $155 | $241,526 | 8 | Sony Pictures Releasing | false | false |
| 41 | 37 | The Secret Life of Bees | $397 | -24.5% | 8 | +5 | $49 | $17,672 | 5 | 20th Century Fox International | false | false |
| 42 | 42 | Lovely Loneliness | $394 | +34.9% | 2 | +1 | $197 | $47,793 | 6 | Pachamama Cine | false | false |
| 43 | 52 | Underworld: Rise of the Lycans | $333 | +851.4% | 1 | - | $333 | $375,781 | 10 | Sony Pictures Releasing | false | false |
| 44 | 31 | Madagascar: Escape 2 Africa | $133 | -87.9% | 1 | -2 | $133 | $5,065,670 | 19 | Paramount Pictures International | false | false |
| 45 | 49 | The Wrestler | $88 | +15.8% | 1 | - | $88 | $191,482 | 8 | Distribution Company | false | false |
| 46 | 46 | The Tale of Despereaux | $68 | -53.1% | 1 | -1 | $68 | $176,458 | 10 | United International Pictures | false | false |
