| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Monsters vs. Aliens | $29,079 | - | 9 | - | $3,231 | $29,079 | 1 | United International Pictures | true | false |
| 2 | 1 | Race to Witch Mountain | $17,250 | +4% | 5 | - | $3,450 | $38,353 | 2 | Walt Disney Pictures | false | false |
| 3 | 2 | Underworld: Rise of the Lycans | $8,515 | -17.7% | 4 | - | $2,128 | $22,247 | 2 | Sony Pictures Releasing | false | false |
| 4 | 4 | Slumdog Millionaire | $7,864 | -14.2% | 3 | -1 | $2,621 | $93,042 | 5 | Europa Filmes | false | false |
| 5 | 3 | Bedtime Stories | $6,339 | -31% | 4 | -1 | $1,584 | $69,226 | 4 | Walt Disney Pictures | false | false |
| 6 | 5 | Hotel for Dogs | $4,809 | -46.6% | 4 | -2 | $1,202 | $32,940 | 3 | Paramount Pictures International | false | false |
| 7 | 7 | Gran Torino | $4,380 | -11.6% | 3 | - | $1,460 | $20,126 | 3 | Warner Bros. | false | false |
| 8 | 8 | I Could Never Be Your Woman | $2,738 | -7.2% | 2 | - | $1,369 | $11,919 | 3 | - | false | false |
| 9 | 10 | Bride Wars | $2,512 | +8.2% | 3 | - | $837 | $60,262 | 7 | 20th Century Fox International | false | false |
| 10 | 11 | Lust, Caution | $1,075 | -38.6% | 1 | -1 | $1,075 | $3,717 | 2 | - | false | false |
| 11 | - | Eco-Man | $898 | - | 2 | - | $449 | $898 | 1 | N/A | true | false |
| 12 | 9 | Twilight | $809 | -69.2% | 3 | -2 | $269 | $69,373 | 7 | - | false | false |
