| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Duplicity | $262,504 | - | 20 | - | $13,125 | $262,504 | 1 | United International Pictures | true | false |
| 2 | 2 | He's Just Not That Into You | $91,944 | -49% | 16 | -4 | $5,746 | $338,134 | 2 | Italian International Film | false | false |
| 3 | 1 | Friday the 13th | $80,567 | -63.4% | 20 | - | $4,028 | $349,896 | 2 | United International Pictures | false | false |
| 4 | 4 | Race to Witch Mountain | $66,340 | -29.1% | 15 | -3 | $4,422 | $457,618 | 3 | N/A | false | false |
| 5 | 5 | Hotel for Dogs | $62,796 | -20.3% | 15 | -2 | $4,186 | $296,951 | 3 | United International Pictures | false | false |
| 6 | 3 | Mnahy | $46,211 | -52.6% | 10 | -10 | $4,621 | $180,124 | 2 | N/A | false | false |
| 7 | 9 | Slumdog Millionaire | $17,692 | -44.1% | 10 | -2 | $1,769 | $1,286,846 | 10 | Gulf Film | false | false |
| 8 | 7 | Gran Torino | $16,636 | -59.9% | 6 | -3 | $2,772 | $257,382 | 3 | N/A | false | false |
| 9 | - | Henry Poole Is Here | $16,323 | - | 7 | - | $2,331 | $16,323 | 1 | N/A | true | false |
| 10 | 10 | Marley & Me | $14,421 | -39.4% | 3 | -2 | $4,807 | $388,949 | 4 | N/A | false | false |
| 11 | 8 | Trade | $14,353 | -60% | 8 | - | $1,794 | $69,382 | 2 | N/A | false | false |
| 12 | 6 | Nims Bond | $13,381 | -69.1% | 5 | -9 | $2,676 | $192,154 | 3 | N/A | false | false |
| 13 | 14 | The Pink Panther 2 | $9,033 | -12.7% | 1 | -1 | $9,033 | $840,129 | 7 | N/A | false | false |
| 14 | 11 | Jonas Brothers: The 3D Concert Experience | $7,822 | -65.7% | 4 | -4 | $1,955 | $33,794 | 2 | N/A | false | false |
| 15 | 12 | Watchmen | $3,867 | -74.6% | 1 | -13 | $3,867 | $496,468 | 4 | United International Pictures | false | false |
| 16 | 18 | My Mom's New Boyfriend | $1,798 | -0.4% | 1 | - | $1,798 | $165,388 | 9 | N/A | false | false |
| 17 | 20 | Garfield's Fun Fest | $1,627 | +16.3% | 1 | - | $1,627 | $123,280 | 6 | N/A | false | false |
| 18 | 16 | What Just Happened | $1,535 | -64.5% | 1 | -1 | $1,535 | $136,833 | 4 | Gulf Film | false | false |
| 19 | 22 | Twilight | $1,450 | +30.7% | 1 | - | $1,450 | $1,256,608 | 17 | N/A | false | false |
| 20 | 19 | Madagascar: Escape 2 Africa | $1,239 | -19.4% | 1 | - | $1,239 | $1,908,261 | 18 | N/A | false | false |
| 21 | 13 | The Midnight Meat Train | $152 | -98.6% | 1 | -11 | $152 | $119,803 | 3 | N/A | false | false |
