| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Marley & Me | $236,143 | - | 64 | - | $3,689 | $236,143 | 1 | NuMetro Distribution | true | false |
| 2 | 1 | Slumdog Millionaire | $86,613 | -20.4% | 20 | - | $4,330 | $462,329 | 3 | Ster-Kinekor Pictures | false | false |
| 3 | 2 | Confessions of a Shopaholic | $65,615 | -38.6% | 51 | +1 | $1,286 | $212,100 | 2 | Ster-Kinekor Pictures | false | false |
| 4 | 3 | The Pink Panther 2 | $50,327 | -25.8% | 69 | - | $729 | $463,560 | 4 | Ster-Kinekor Pictures | false | false |
| 5 | 5 | The Curious Case of Benjamin Button | $43,011 | -27.7% | 43 | -12 | $1,000 | $453,172 | 4 | NuMetro Distribution | false | false |
| 6 | 4 | Watchmen | $40,801 | -39.3% | 59 | -3 | $691 | $297,018 | 3 | Ster-Kinekor Pictures | false | false |
| 7 | 6 | He's Just Not That Into You | $34,171 | -25.6% | 50 | -1 | $683 | $688,126 | 6 | NuMetro Distribution | false | false |
| 8 | 7 | Paul Blart: Mall Cop | $25,602 | -28.9% | 25 | - | $1,024 | $74,353 | 2 | Ster-Kinekor Pictures | false | false |
| 9 | 8 | Bedtime Stories | $21,748 | -29.5% | 35 | -7 | $621 | $595,436 | 8 | Ster-Kinekor Pictures | false | false |
| 10 | - | Hond se Dinges | $19,652 | - | 32 | - | $614 | $26,868 | 1 | Ster-Kinekor Pictures | true | false |
| 11 | 11 | Rachel Getting Married | $13,378 | -21.2% | 10 | - | $1,337 | $39,568 | 2 | Ster-Kinekor Pictures | false | false |
| 12 | - | Defiance | $13,186 | - | 10 | - | $1,318 | $13,186 | 1 | United International Pictures | true | false |
| 13 | 10 | Seven Pounds | $11,910 | -31.8% | 20 | - | $595 | $307,615 | 6 | Ster-Kinekor Pictures | false | false |
| 14 | 9 | New in Town | $10,052 | -66.2% | 31 | -22 | $324 | $130,985 | 3 | NuMetro Distribution | false | false |
| 15 | 12 | Friday the 13th | $9,037 | -31.9% | 10 | - | $903 | $26,874 | 2 | United International Pictures | false | false |
| 16 | 16 | Passengers | $8,292 | -19.7% | 10 | - | $829 | $28,222 | 2 | NuMetro Distribution | false | false |
| 17 | 13 | Changeling | $7,948 | -39.7% | 12 | -8 | $662 | $175,289 | 5 | United International Pictures | false | false |
| 18 | 14 | Inkheart | $7,457 | -39.7% | 18 | -6 | $414 | $163,036 | 5 | NuMetro Distribution | false | false |
| 19 | 17 | Notorious | $6,676 | -16.7% | 16 | - | $417 | $131,117 | 5 | NuMetro Distribution | false | false |
| 20 | 18 | The Secret Life of Bees | $5,838 | -21.8% | 19 | +2 | $307 | $171,285 | 7 | NuMetro Distribution | false | false |
| 21 | 20 | The Longshots | $3,019 | -40.3% | 8 | -2 | $377 | $43,885 | 4 | Ster-Kinekor Pictures | false | false |
| 22 | 21 | Transporter 3 | $2,084 | -54.7% | 9 | -5 | $231 | $765,130 | 10 | United International Pictures | false | false |
| 23 | - | Vicky Cristina Barcelona | $2,034 | - | 3 | - | $678 | $202,899 | 12 | United International Pictures | false | false |
| 24 | 23 | Revolutionary Road | $1,708 | -56.8% | 6 | -9 | $284 | $202,688 | 9 | United International Pictures | false | false |
| 25 | 24 | The Wrestler | $1,611 | -47% | 7 | -2 | $230 | $55,296 | 5 | United International Pictures | false | false |
| 26 | 22 | Role Models | $1,580 | -60.6% | 9 | -2 | $175 | $212,399 | 7 | United International Pictures | false | false |
| 27 | 26 | Frost/Nixon | $1,010 | -9.6% | 2 | - | $505 | $45,255 | 8 | United International Pictures | false | false |
| 28 | - | Four Christmases | $188 | - | 1 | - | $188 | $508,053 | 11 | NuMetro Distribution | false | false |
| 29 | - | Burn After Reading | $151 | - | 1 | - | $151 | $277,600 | 11 | Ster-Kinekor Pictures | false | false |
| 30 | - | Appaloosa | $142 | - | 1 | - | $142 | $21,387 | 6 | NuMetro Distribution | false | false |
