| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Another Egg and Chicken Movie | $2,225,866 | - | 441 | - | $5,047 | $2,225,866 | 1 | Videocine | true | false |
| 2 | 1 | The Unborn | $728,029 | -43.7% | 352 | - | $2,068 | $2,953,891 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | 2 | Paul Blart: Mall Cop | $301,763 | -51.5% | 302 | +2 | $999 | $1,329,804 | 2 | Sony Pictures Releasing | false | false |
| 4 | 3 | Slumdog Millionaire | $265,814 | -36.1% | 206 | -13 | $1,290 | $3,945,227 | 5 | Gussi Films | false | false |
| 5 | - | The International | $190,365 | - | 150 | - | $1,269 | $190,365 | 1 | Sony Pictures Releasing | true | false |
| 6 | 4 | Watchmen | $163,297 | -56.7% | 291 | -129 | $561 | $1,891,855 | 3 | Paramount Pictures International | false | false |
| 7 | 5 | He's Just Not That Into You | $143,041 | -43.5% | 117 | -106 | $1,222 | $1,165,181 | 3 | Gussi Films | false | false |
| 8 | 11 | Changeling | $130,086 | -10.8% | 145 | -6 | $897 | $1,261,651 | 4 | Universal Pictures International (UPI) | false | false |
| 9 | 7 | Underworld: Rise of the Lycans | $127,686 | -45.4% | 183 | -41 | $697 | $3,612,048 | 7 | Sony Pictures Releasing | false | false |
| 10 | - | Last Chance Harvey | $98,110 | - | 60 | - | $1,635 | $103,718 | 1 | Gussi Films | true | false |
| 11 | 9 | Big Stan | $91,108 | -42.3% | 117 | -58 | $778 | $1,588,000 | 7 | Videocine | false | false |
| 12 | 6 | The Pink Panther 2 | $72,879 | -70.7% | 189 | -135 | $385 | $2,052,929 | 4 | Sony Pictures Releasing | false | false |
| 13 | 23 | Righteous Kill | $71,944 | +94.3% | 74 | +30 | $972 | $818,981 | 7 | Corazón Films | false | false |
| 14 | 8 | Jonas Brothers: The 3D Concert Experience | $65,638 | -69.6% | 64 | -61 | $1,025 | $880,368 | 3 | Walt Disney Pictures | false | false |
| 15 | 18 | Doubt | $45,949 | +7% | 52 | +9 | $883 | $579,662 | 5 | Walt Disney Pictures | false | false |
| 16 | 20 | The Wrestler | $45,541 | +13.2% | 61 | -15 | $746 | $350,917 | 4 | Corazón Films | false | false |
| 17 | 15 | Transporter 3 | $41,615 | -40.6% | 67 | -27 | $621 | $357,424 | 5 | Zima Entertainment | false | false |
| 18 | 14 | Milk | $35,780 | -52.6% | 41 | -28 | $872 | $353,667 | 3 | Universal Pictures International (UPI) | false | false |
| 19 | 29 | To Love | $34,652 | +41% | 91 | +7 | $380 | $476,485 | 4 | Gussi Films | false | false |
| 20 | 25 | Revolutionary Road | $32,347 | -8.3% | 55 | - | $588 | $874,617 | 8 | Paramount Pictures International | false | false |
| 21 | 17 | Confessions of a Shopaholic | $27,805 | -49.7% | 47 | -43 | $591 | $981,234 | 6 | Walt Disney Pictures | false | false |
| 22 | - | In Bruges | $27,114 | - | 60 | - | $451 | $27,114 | 1 | Corazón Films | true | false |
| 23 | 10 | Agent Macaw: Shaken & Stirred | $26,923 | -82% | 122 | -105 | $220 | $1,353,434 | 6 | Videocine | false | false |
| 24 | 12 | Coraline | $24,697 | -80.8% | 99 | -113 | $249 | $4,444,529 | 7 | Universal Pictures International (UPI) | false | false |
| 25 | 19 | My Sassy Girl | $19,472 | -53.7% | 52 | -38 | $374 | $294,184 | 4 | Videocine | false | false |
| 26 | 22 | Friday the 13th | $17,625 | -55.4% | 52 | -46 | $338 | $679,393 | 6 | Sony Pictures Releasing | false | false |
| 27 | 13 | Valkyrie | $14,042 | -83.5% | 35 | -130 | $401 | $4,129,742 | 6 | 20th Century Fox International | false | false |
| 28 | 38 | The Spirit | $13,448 | -1.8% | 33 | -1 | $407 | $430,036 | 9 | Sony Pictures Releasing | false | false |
| 29 | 16 | Elegy | $11,228 | -79.9% | 27 | -53 | $415 | $111,879 | 2 | Corazón Films | false | false |
| 30 | 42 | The Duchess | $9,597 | -17.9% | 13 | -4 | $738 | $480,376 | 18 | Paramount Pictures International | false | false |
| 31 | 28 | My Bloody Valentine | $8,217 | -73.3% | 31 | -53 | $265 | $1,650,144 | 6 | Gussi Films | false | false |
| 32 | 31 | Backyard | $7,546 | -64.7% | 22 | -51 | $343 | $723,600 | 5 | Paramount Pictures International | false | false |
| 33 | 45 | Blind Dating 2009 Re-release | $4,545 | -49.8% | 11 | -22 | $413 | $62,075 | 5 | Quality Films | false | false |
| 34 | 24 | The Secret Life of Bees | $2,778 | -92.4% | 14 | -36 | $198 | $66,536 | 2 | 20th Century Fox International | false | false |
| 35 | 40 | Desierto adentro | $2,767 | -77.7% | 20 | - | $138 | $24,681 | 2 | Gussi Films | false | false |
| 36 | 41 | Yes Man | $2,352 | -80.5% | 8 | -26 | $294 | $4,628,487 | 8 | Warner Bros. | false | false |
| 37 | 66 | Frost/Nixon | $2,335 | -15.2% | 6 | -6 | $389 | $95,080 | 7 | Universal Pictures International (UPI) | false | false |
| 38 | 54 | All the Boys Love Mandy Lane | $2,329 | -54.1% | 10 | -13 | $232 | $49,113 | 3 | Zima Entertainment | false | false |
| 39 | 37 | Role Models | $2,012 | -85.4% | 8 | -49 | $251 | $276,122 | 5 | Universal Pictures International (UPI) | false | false |
| 40 | 43 | Bride Wars | $1,899 | -83.2% | 4 | -18 | $474 | $2,482,279 | 8 | 20th Century Fox International | false | false |
| 41 | 47 | Inkheart | $1,685 | -80.1% | 11 | -22 | $153 | $2,204,526 | 8 | Gussi Films | false | false |
| 42 | 81 | Fierce People | $1,569 | -2.6% | 10 | -19 | $156 | $36,991 | 3 | Videocine | false | false |
| 43 | 77 | Frozen River | $941 | -45.5% | 5 | +1 | $188 | $76,710 | 20 | Sony Pictures Releasing | false | false |
| 44 | 52 | Timecrimes | $689 | -88.4% | 6 | -12 | $114 | $97,468 | 7 | David Distribucion | false | false |
| 45 | 83 | Seven Pounds | $622 | -56.8% | 1 | -6 | $622 | $4,293,649 | 11 | Sony Pictures Releasing | false | false |
| 46 | 64 | Quarantine | $330 | -88.1% | 9 | -4 | $36 | $474,668 | 8 | Sony Pictures Releasing | false | false |
| 47 | 78 | Lakeview Terrace | $43 | -97.5% | 3 | -8 | $14 | $304,856 | 18 | Sony Pictures Releasing | false | false |
