| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Gran Torino | $147,196 | -29.5% | 47 | +3 | $3,131 | $418,354 | 2 | Warner Bros. | false | false |
| 2 | 2 | He's Just Not That Into You | $138,236 | -26.7% | 31 | - | $4,459 | $383,417 | 2 | Distribution Company | false | false |
| 3 | 4 | Slumdog Millionaire | $131,450 | -19.8% | 43 | -4 | $3,056 | $1,062,149 | 5 | Distribution Company | false | false |
| 4 | - | Transporter 3 | $118,709 | - | 42 | - | $2,826 | $118,709 | 1 | - | true | false |
| 5 | - | Gomorrah | $91,070 | - | 31 | - | $2,937 | $91,070 | 1 | Alfa Films | true | false |
| 6 | 5 | Bedtime Stories | $90,491 | -31.7% | 79 | - | $1,145 | $1,923,108 | 6 | Walt Disney Pictures | false | false |
| 7 | 3 | Watchmen | $79,938 | -56.5% | 46 | +1 | $1,737 | $312,338 | 2 | Paramount Pictures International | false | false |
| 8 | 6 | The Curious Case of Benjamin Button | $77,776 | -37% | 73 | +2 | $1,065 | $1,919,175 | 6 | Warner Bros. | false | false |
| 9 | - | Paris | $62,503 | - | 15 | - | $4,166 | $62,503 | 1 | Impacto Cine | true | false |
| 10 | 7 | Bride Wars | $46,940 | -41.9% | 42 | -1 | $1,117 | $302,276 | 3 | 20th Century Fox International | false | false |
| 11 | - | Coraline | $42,024 | - | 23 | - | $1,827 | $42,024 | 1 | Universal Pictures International (UPI) | true | false |
| 12 | 11 | Vicky Cristina Barcelona | $34,282 | -29.5% | 32 | - | $1,071 | $717,738 | 6 | Pachamama Cine | false | false |
| 13 | 8 | Hotel for Dogs | $32,214 | -51.9% | 38 | -3 | $847 | $487,742 | 4 | Paramount Pictures International | false | false |
| 14 | 9 | Seven Pounds | $29,438 | -45.1% | 26 | -2 | $1,132 | $194,915 | 3 | Sony Pictures Releasing | false | false |
| 15 | - | Be Kind Rewind | $21,153 | - | 18 | - | $1,175 | $21,153 | 1 | Distribution Company | true | false |
| 16 | 13 | Friday the 13th | $20,276 | -25.4% | 35 | +5 | $579 | $348,770 | 5 | Paramount Pictures International | false | false |
| 17 | 10 | Valkyrie | $19,458 | -62.7% | 61 | -6 | $318 | $717,844 | 5 | 20th Century Fox International | false | false |
| 18 | 12 | The Pink Panther 2 | $13,244 | -62% | 26 | +1 | $509 | $216,908 | 4 | Sony Pictures Releasing | false | false |
| 19 | - | The Window | $13,023 | - | 9 | - | $1,447 | $13,023 | 1 | Distribution Company | true | false |
| 20 | 14 | Milk | $10,894 | -53.7% | 26 | -7 | $419 | $231,426 | 5 | Universal Pictures International (UPI) | false | false |
| 21 | 16 | Yes Man | $9,898 | -52.5% | 22 | -25 | $449 | $1,314,543 | 9 | Warner Bros. | false | false |
| 22 | 19 | Doubt | $7,249 | -14.7% | 20 | +3 | $362 | $538,548 | 9 | Walt Disney Pictures | false | false |
| 23 | - | The Secret Life of Bees | $7,024 | - | 10 | - | $702 | $7,024 | 1 | 20th Century Fox International | true | false |
| 24 | 17 | Changeling | $7,020 | -59.3% | 32 | -7 | $219 | $901,957 | 8 | Universal Pictures International (UPI) | false | false |
| 25 | 15 | Lovely Loneliness | $6,870 | -70.8% | 8 | -3 | $858 | $36,819 | 2 | Pachamama Cine | false | false |
| 26 | 21 | Unfair Competition 2009 Re-release | $5,639 | -32.5% | 5 | +1 | $1,127 | $16,556 | 2 | Primer Plano Film Group | false | false |
| 27 | 18 | The Wrestler | $4,069 | -75.2% | 27 | -3 | $150 | $187,696 | 4 | Distribution Company | false | false |
| 28 | 22 | Revolutionary Road | $2,443 | -47.8% | 14 | -4 | $174 | $293,679 | 7 | Paramount Pictures International | false | false |
| 29 | - | Sex Drive | $1,772 | - | 3 | - | $590 | $34,018 | 7 | Alfa Films | false | false |
| 30 | 28 | Frost/Nixon | $1,685 | -18.7% | 4 | -2 | $421 | $43,391 | 4 | United International Pictures | false | false |
| 31 | 41 | Blame it on Fidel | $1,432 | +406% | 5 | +4 | $286 | $37,238 | 8 | Zeta Films | false | false |
| 32 | 20 | Underworld: Rise of the Lycans | $1,306 | -84.5% | 5 | -11 | $261 | $373,333 | 6 | Sony Pictures Releasing | false | false |
| 33 | 26 | Bolt | $1,284 | -56.4% | 11 | -18 | $116 | $2,184,684 | 9 | Walt Disney Pictures | false | false |
| 34 | 23 | Death Proof | $977 | -79.1% | 4 | -9 | $244 | $34,282 | 3 | Pachamama Cine | false | false |
| 35 | 24 | Rodney | $943 | -73.4% | 4 | -10 | $235 | $5,995 | 2 | Primer Plano Film Group | false | false |
| 36 | 31 | Inkheart | $893 | -41.5% | 9 | -3 | $99 | $364,528 | 7 | Distribution Company | false | false |
| 37 | 32 | The Tale of Despereaux | $630 | -58.2% | 7 | -7 | $90 | $180,758 | 6 | United International Pictures | false | false |
| 38 | 38 | The Day the Earth Stood Still | $626 | +31.5% | 4 | -1 | $156 | $1,897,427 | 11 | 20th Century Fox International | false | false |
| 39 | 30 | Twilight | $613 | -61.7% | 6 | -1 | $102 | $1,844,290 | 11 | Alfa Films | false | false |
| 40 | 25 | L'année suivante | $558 | -81.2% | 4 | +1 | $139 | $12,254 | 3 | Zeta Films | false | false |
| 41 | 29 | Marley & Me | $393 | -80.7% | 2 | -10 | $196 | $637,908 | 8 | 20th Century Fox International | false | false |
| 42 | - | Back to Fortin Olmos | $336 | - | 1 | - | $336 | $1,112 | 2 | Primer Plano Film Group | false | false |
| 43 | 33 | Am Ende kommen Touristen | $272 | -77.3% | 2 | -2 | $136 | $14,249 | 4 | Alfa Films | false | false |
| 44 | 34 | High School Musical 3: Senior Year | $268 | -59.8% | 2 | -1 | $134 | $1,314,220 | 16 | Walt Disney Pictures | false | false |
| 45 | 43 | El ratón Pérez 2 | $177 | +67% | 2 | +1 | $88 | $703,034 | 11 | Walt Disney Pictures | false | false |
| 46 | 36 | Australia | $169 | -69.3% | 3 | -5 | $56 | $818,385 | 10 | 20th Century Fox International | false | false |
| 47 | 39 | Che: Part One | $133 | -70.4% | 1 | -1 | $133 | $669,222 | 18 | Alfa Films | false | false |
| 48 | 40 | The Camera Obscura 2008 Re-release | $79 | -72.3% | 1 | -1 | $79 | $64,009 | 22 | Distribution Company | false | false |
| 49 | 42 | Madagascar: Escape 2 Africa | $63 | -73.3% | 4 | -1 | $15 | $5,228,773 | 15 | Paramount Pictures International | false | false |
