| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Slumdog Millionaire | $974,690 | - | 74 | - | $13,171 | $974,690 | 1 | Audio Visual Enterprises | true | false |
| 2 | - | Marley & Me | $301,730 | - | 40 | - | $7,543 | $301,730 | 1 | Odeon | true | false |
| 3 | 1 | Gran Torino | $219,947 | -48.6% | 31 | - | $7,095 | $652,834 | 2 | Roadshow Films | false | false |
| 4 | 2 | Guiness | $103,282 | -54.7% | 48 | -3 | $2,151 | $345,314 | 2 | Village Films | false | false |
| 5 | 3 | Valkyrie | $85,885 | -56.9% | 40 | - | $2,147 | $715,153 | 3 | Odeon | false | false |
| 6 | 4 | The Pink Panther 2 | $85,200 | -51.2% | 44 | -22 | $1,936 | $1,698,400 | 4 | Sony Pictures Releasing | false | false |
| 7 | 5 | Eden Is West | $83,045 | -49.9% | 30 | - | $2,768 | $542,441 | 3 | Odeon | false | false |
| 8 | 10 | The Tale of Despereaux | $81,920 | +7.8% | 34 | +2 | $2,409 | $174,356 | 2 | United International Pictures | false | false |
| 9 | 8 | Bolt | $80,247 | -1.4% | 62 | -4 | $1,294 | $808,963 | 5 | Audio Visual Enterprises | false | false |
| 10 | - | Slaves in Their Bonds | $69,320 | - | 13 | - | $5,332 | $69,320 | 1 | Seven Films | true | false |
| 11 | 7 | He's Just Not That Into You | $65,700 | -40.3% | 19 | -8 | $3,457 | $608,820 | 3 | Village Films | false | false |
| 12 | 6 | Push | $61,232 | -49.5% | 16 | - | $3,827 | $208,050 | 2 | Odeon | false | false |
| 13 | 11 | The Unborn | $47,664 | -28.7% | 15 | -1 | $3,177 | $324,730 | 3 | United International Pictures | false | false |
| 14 | 9 | The Reader | $46,089 | -43.1% | 14 | - | $3,292 | $1,624,838 | 9 | Odeon | false | false |
| 15 | 12 | Seven Pounds | $26,705 | -58.4% | 15 | -1 | $1,780 | $120,617 | 2 | Sony Pictures Releasing | false | false |
| 16 | 13 | The Dust of Time | $24,999 | -54.3% | 14 | -1 | $1,785 | $402,062 | 4 | Audio Visual Enterprises | false | false |
| 17 | 20 | Doubt | $13,753 | -32% | 5 | -1 | $2,750 | $689,051 | 6 | Audio Visual Enterprises | false | false |
| 18 | 15 | Milk | $13,123 | -64.2% | 6 | -8 | $2,187 | $435,238 | 8 | Odeon | false | false |
| 19 | 22 | Madagascar: Escape 2 Africa | $10,789 | +7.5% | 16 | -4 | $674 | $3,301,467 | 12 | United International Pictures | false | false |
| 20 | 14 | I'm Dying for You! | $10,589 | -76.2% | 6 | -13 | $1,764 | $2,079,109 | 6 | Odeon | false | false |
| 21 | 16 | My Bloody Valentine | $9,603 | -70.6% | 5 | -3 | $1,920 | $140,664 | 3 | Spentzos Films | false | false |
| 22 | - | The Spring Gathering | $8,541 | - | 2 | - | $4,270 | $8,541 | 1 | New Star | true | false |
| 23 | 18 | The Wrestler | $7,906 | -72.1% | 9 | -12 | $878 | $547,172 | 5 | Spentzos Films | false | false |
| 24 | - | Boobheads | $6,570 | - | 4 | - | $1,642 | $6,570 | 1 | - | true | false |
| 25 | 23 | Underworld: Rise of the Lycans | $4,065 | -13.8% | 6 | -6 | $677 | $1,224,361 | 7 | Audio Visual Enterprises | false | false |
| 26 | - | My Only Sunshine | $2,628 | - | 2 | - | $1,314 | $2,648 | 1 | Filmtrade | true | false |
| 27 | 21 | Rachel Getting Married | $1,529 | -85.1% | 2 | -3 | $764 | $55,643 | 3 | Audio Visual Enterprises | false | false |
| 28 | 27 | Fly Me to the Moon 3D | $701 | -47.3% | 4 | - | $175 | $502,838 | 17 | Odeon | false | false |
