| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Gran Torino | $2,683,115 | - | 245 | - | $10,951 | $2,683,115 | 1 | Warner Bros. | true | false |
| 2 | - | Bedtime Stories | $2,038,321 | - | 400 | - | $5,095 | $2,038,321 | 1 | Walt Disney Pictures | true | false |
| 3 | - | Watchmen | $1,938,521 | - | 426 | - | $4,550 | $1,938,521 | 1 | Paramount Pictures International | true | false |
| 4 | 1 | Slumdog Millionaire | $1,475,912 | -34.6% | 252 | +2 | $5,856 | $8,088,420 | 4 | Filmax | false | false |
| 5 | 2 | The Pink Panther 2 | $814,124 | -59.3% | 386 | -11 | $2,109 | $2,980,694 | 2 | Sony Pictures Releasing | false | false |
| 6 | - | The Code | $784,404 | - | 218 | - | $3,598 | $784,404 | 1 | DeAPlaneta | true | false |
| 7 | 3 | The Curious Case of Benjamin Button | $701,405 | -49.5% | 400 | -49 | $1,753 | $14,298,025 | 5 | Warner Bros. | false | false |
| 8 | 4 | The Reader | $551,841 | -38.3% | 205 | -5 | $2,691 | $4,295,905 | 4 | On Pictures | false | false |
| 9 | 5 | Beverly Hills Chihuahua | $397,091 | -54.6% | 297 | -3 | $1,337 | $7,026,815 | 5 | Walt Disney Pictures | false | false |
| 10 | 6 | Push | $267,441 | -65.6% | 257 | -19 | $1,040 | $2,554,502 | 3 | - | false | false |
| 11 | 8 | Che: Part Two | $205,342 | -58.7% | 250 | +1 | $821 | $851,788 | 2 | 20th Century Fox International | false | false |
| 12 | 7 | In the Name of the King: A Dungeon Siege Tale | $197,519 | -70.9% | 217 | -1 | $910 | $1,020,535 | 2 | New World Pictures | false | false |
| 13 | 12 | Doubt | $102,764 | -53.1% | 100 | -25 | $1,027 | $3,052,474 | 6 | Walt Disney Pictures | false | false |
| 14 | 11 | Seven Pounds | $77,206 | -66.5% | 127 | -96 | $607 | $13,354,595 | 8 | Sony Pictures Releasing | false | false |
| 15 | - | Cherry Blossoms | $61,741 | - | 35 | - | $1,764 | $61,741 | 1 | Wanda Visión S.A. | true | false |
| 16 | 14 | Welcome to the Sticks | $60,973 | -51% | 70 | -39 | $871 | $4,184,725 | 9 | Wanda Visión S.A. | false | false |
| 17 | 9 | The Wrestler | $56,457 | -77.2% | 95 | -60 | $594 | $961,204 | 3 | United International Pictures | false | false |
| 18 | 10 | Valkyrie | $53,400 | -77.4% | 91 | -158 | $586 | $7,517,434 | 6 | 20th Century Fox International | false | false |
| 19 | 15 | Revolutionary Road | $50,200 | -56.9% | 65 | -60 | $772 | $5,151,894 | 7 | Paramount Pictures International | false | false |
| 20 | 13 | Friday the 13th | $47,004 | -77.1% | 80 | -127 | $587 | $1,779,548 | 4 | Paramount Pictures International | false | false |
| 21 | 18 | Let it Rain | $45,190 | -33.7% | 28 | -1 | $1,613 | $140,552 | 2 | - | false | false |
| 22 | 19 | The Class | $38,346 | -34.5% | 32 | -21 | $1,198 | $1,541,439 | 8 | Golem Distribución | false | false |
| 23 | 21 | The Milk of Sorrow | $22,741 | -40.8% | 21 | -5 | $1,082 | $181,790 | 4 | Wanda Visión S.A. | false | false |
| 24 | 16 | Milk | $19,093 | -77.2% | 35 | -64 | $545 | $1,662,096 | 9 | United International Pictures | false | false |
| 25 | 22 | Waltz with Bashir | $18,300 | -52.1% | 20 | -11 | $915 | $154,040 | 3 | Golem Distribución | false | false |
| 26 | 36 | The Hanged Man | $12,954 | +30.3% | 12 | -4 | $1,079 | $457,766 | 6 | Sony Pictures Releasing | false | false |
| 27 | 20 | Bolt | $12,804 | -69.8% | 54 | -4 | $237 | $10,311,293 | 14 | Walt Disney Pictures | false | false |
| 28 | 34 | El Zorro de San Adrian | $11,911 | -7.8% | 14 | - | $850 | $96,654 | 5 | Barton Films | false | false |
| 29 | 25 | The Missing Lynx | $11,515 | -68.2% | 40 | -18 | $287 | $1,429,163 | 11 | - | false | false |
| 30 | 23 | Julia | $10,418 | -72.4% | 21 | -9 | $496 | $63,732 | 2 | Vértigo Films | false | false |
| 31 | 38 | El libro de las aguas | $8,300 | -10% | 5 | -1 | $1,660 | $147,889 | 17 | Independent Films | false | false |
| 32 | 29 | The Way | $8,057 | -66.5% | 11 | -26 | $732 | $2,139,173 | 21 | Alta Films | false | false |
| 33 | 26 | Mediterranean Food | $7,787 | -75.7% | 10 | -37 | $778 | $814,152 | 5 | Alta Films | false | false |
| 34 | 17 | Ghost Town | $7,718 | -90.5% | 36 | -24 | $214 | $105,928 | 2 | Paramount Pictures International | false | false |
| 35 | 33 | Frost/Nixon | $6,337 | -53% | 8 | -16 | $792 | $429,322 | 5 | Universal Pictures International (UPI) | false | false |
| 36 | 35 | The Tale of Despereaux | $5,601 | -55.7% | 18 | -5 | $311 | $3,473,708 | 12 | Universal Pictures International (UPI) | false | false |
| 37 | 42 | In Search of a Midnight Kiss | $4,858 | -16.6% | 2 | -1 | $2,429 | $429,120 | 14 | Sherlock Films | false | false |
| 38 | 28 | Role Models | $4,152 | -85.5% | 16 | -41 | $259 | $1,667,849 | 6 | Universal Pictures International (UPI) | false | false |
| 39 | 30 | Bride Wars | $3,650 | -84.5% | 19 | -33 | $192 | $3,421,155 | 8 | 20th Century Fox International | false | false |
| 40 | 47 | The Secret of the Grain | $3,445 | -6.4% | 5 | - | $689 | $189,405 | 6 | Vértigo Films | false | false |
| 41 | 32 | Madagascar: Escape 2 Africa | $3,260 | -76.1% | 22 | -17 | $148 | $19,603,189 | 15 | Paramount Pictures International | false | false |
| 42 | 31 | Australia | $2,849 | -87.9% | 14 | -22 | $203 | $14,152,623 | 11 | 20th Century Fox International | false | false |
| 43 | 27 | Transporter 3 | $2,790 | -91.3% | 19 | -41 | $146 | $3,527,536 | 7 | DeAPlaneta | false | false |
| 44 | 40 | The Unborn | $2,409 | -68.5% | 9 | -17 | $267 | $3,325,341 | 8 | Universal Pictures International (UPI) | false | false |
| 45 | 37 | The Broken | $2,249 | -77.1% | 6 | -3 | $374 | $15,044 | 2 | Independent Films | false | false |
| 46 | 44 | Twilight | $2,190 | -58.9% | 13 | -4 | $168 | $15,830,746 | 14 | - | false | false |
| 47 | 41 | Changeling | $2,104 | -71.5% | 4 | -9 | $526 | $10,371,374 | 12 | Universal Pictures International (UPI) | false | false |
| 48 | 48 | The One-Handed Trick | $1,424 | -56.7% | 3 | -5 | $474 | $489,961 | 8 | Alta Films | false | false |
| 49 | 46 | Winx Club: The Secret of the Lost Kingdom | $1,298 | -69.3% | 11 | -7 | $118 | $459,221 | 12 | Filmax | false | false |
| 50 | 52 | My Blueberry Nights | $1,182 | -40.4% | 1 | -1 | $1,182 | $1,137,529 | 13 | Vértigo Films | false | false |
| 51 | 53 | The Wave | $1,175 | -23.7% | 5 | -1 | $235 | $1,677,183 | 15 | - | false | false |
| 52 | 43 | El ratón Pérez 2 | $1,131 | -79.8% | 6 | -4 | $188 | $1,118,068 | 13 | Filmax | false | false |
| 53 | 45 | Cadillac Records | $663 | -87.5% | 3 | -12 | $221 | $38,804 | 3 | Sony Pictures Releasing | false | false |
| 54 | 59 | A Complete History of My Sexual Failures | $474 | -18.7% | 3 | -2 | $158 | $43,170 | 4 | Avalon | false | false |
| 55 | 55 | Gomorrah | $468 | -62.8% | 3 | -3 | $156 | $3,281,555 | 17 | Alta Films | false | false |
| 56 | 51 | Yes Man | $377 | -81.2% | 1 | -7 | $377 | $5,972,772 | 12 | Warner Bros. | false | false |
| 57 | 57 | Forever Waiting | $314 | -64.2% | 2 | -5 | $157 | $12,709 | 3 | Barton Films | false | false |
| 58 | 61 | RocknRolla | $292 | -47% | 2 | -4 | $146 | $1,383,444 | 10 | Warner Bros. | false | false |
| 59 | 50 | Easy Virtue | $221 | -90.8% | 2 | -1 | $110 | $1,904,675 | 10 | DeAPlaneta | false | false |
| 60 | 39 | Big Stan | $206 | -97.3% | 4 | -16 | $51 | $1,446,442 | 7 | - | false | false |
| 61 | 56 | Rachel Getting Married | $98 | -89.8% | 1 | -1 | $98 | $283,439 | 19 | Sony Pictures Releasing | false | false |
| 62 | 49 | The Last Deadly Mission | $92 | -97.1% | 2 | -6 | $46 | $4,168 | 2 | Versus Entertainment | false | false |
| 63 | 60 | Quarantine | $25 | -95.7% | 1 | -1 | $25 | $1,241,997 | 9 | Filmax | false | false |
