| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Slumdog Millionaire | $48,809 | - | 2 | - | $24,404 | $48,809 | 1 | ACME | true | false |
| 2 | 1 | Bolt | $20,096 | -24.9% | 8 | - | $2,512 | $134,111 | 3 | - | false | false |
| 3 | 2 | The Pink Panther 2 | $11,967 | -48.8% | 4 | - | $2,991 | $44,615 | 2 | Universal Pictures International (UPI) | false | false |
| 4 | 3 | He's Just Not That Into You | $11,758 | -28.7% | 3 | - | $3,919 | $80,162 | 3 | Universal Pictures International (UPI) | false | false |
| 5 | - | The International | $10,645 | - | 2 | - | $5,322 | $10,645 | 1 | Universal Pictures International (UPI) | true | false |
| 6 | 4 | The Curious Case of Benjamin Button | $7,568 | -26% | 4 | - | $1,892 | $137,455 | 5 | Universal Pictures International (UPI) | false | false |
| 7 | 5 | Yes Man | $6,836 | -22.4% | 4 | - | $1,709 | $206,040 | 8 | Universal Pictures International (UPI) | false | false |
| 8 | 6 | My Bloody Valentine | $6,319 | -12.8% | 1 | - | $6,319 | $212,960 | 7 | ACME | false | false |
| 9 | - | Hotel for Dogs | $5,534 | - | 2 | - | $2,767 | $5,534 | 1 | Universal Pictures International (UPI) | true | false |
| 10 | 9 | The Return of the Musketeers, or The Treasures of Cardinal Mazarin | $4,218 | -30.6% | 3 | - | $1,406 | $49,603 | 3 | ACME | false | false |
| 11 | 7 | Underworld: Rise of the Lycans | $3,600 | -46% | 3 | - | $1,200 | $58,991 | 4 | Universal Pictures International (UPI) | false | false |
| 12 | 8 | Valkyrie | $2,355 | -62.4% | 2 | - | $1,177 | $50,421 | 4 | Universal Pictures International (UPI) | false | false |
| 13 | - | Doubt | $2,333 | - | 1 | - | $2,333 | $2,333 | 1 | Universal Pictures International (UPI) | true | false |
| 14 | 11 | Defiance | $1,794 | -52.8% | 2 | - | $897 | $10,261 | 2 | ACME | false | false |
| 15 | 12 | Frost/Nixon | $1,572 | -56.4% | 1 | - | $1,572 | $7,608 | 2 | Universal Pictures International (UPI) | false | false |
| 16 | 10 | Revolutionary Road | $1,458 | -67.3% | 2 | - | $729 | $37,144 | 4 | Universal Pictures International (UPI) | false | false |
| 17 | 15 | Madagascar: Escape 2 Africa | $1,008 | -8.2% | 9 | - | $112 | $355,784 | 12 | Universal Pictures International (UPI) | false | false |
| 18 | 13 | Rachel Getting Married | $651 | -72.2% | 1 | - | $651 | $11,559 | 3 | Universal Pictures International (UPI) | false | false |
