| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Valkyrie | $508,944 | -51.4% | 220 | -4 | $2,313 | $2,051,100 | 2 | 20th Century Fox International | false | false |
| 2 | - | The Pink Panther 2 | $432,163 | - | 251 | - | $1,721 | $18,865,472 | 1 | Sony Pictures Releasing | true | false |
| 3 | 2 | If I Were You 2 | $340,089 | -37.7% | 287 | -6 | $1,184 | $18,255,696 | 8 | 20th Century Fox International | false | false |
| 4 | 3 | The Curious Case of Benjamin Button | $339,870 | -36.6% | 199 | - | $1,707 | $6,578,701 | 6 | Warner Bros. | false | false |
| 5 | 4 | Yes Man | $277,352 | -47.1% | 151 | +1 | $1,836 | $3,157,790 | 4 | Warner Bros. | false | false |
| 6 | - | Hotel for Dogs | $221,016 | - | 130 | - | $1,700 | $221,016 | 1 | Paramount Pictures International | true | false |
| 7 | - | Milk | $123,063 | - | 50 | - | $2,461 | $123,063 | 1 | Universal Pictures International (UPI) | true | false |
| 8 | 12 | The Wrestler | $119,988 | -1.3% | 25 | -23 | $4,799 | $306,381 | 2 | Paris Filmes | false | false |
| 9 | 6 | Coraline | $116,912 | -68.6% | 159 | -1 | $735 | $634,806 | 2 | Universal Pictures International (UPI) | false | false |
| 10 | 9 | The Reader | $101,335 | -45% | 63 | -5 | $1,608 | $765,778 | 3 | Imagem Filmes | false | false |
| 11 | 7 | Bride Wars | $98,651 | -65.8% | 138 | -21 | $714 | $1,194,831 | 3 | 20th Century Fox International | false | false |
| 12 | 5 | Friday the 13th | $87,083 | -77.9% | 145 | -15 | $600 | $613,061 | 2 | Paramount Pictures International | false | false |
| 13 | 8 | Bedtime Stories | $66,354 | -67.3% | 157 | -37 | $422 | $2,951,106 | 5 | Walt Disney Pictures | false | false |
| 14 | 13 | Rachel Getting Married | $45,173 | -32.1% | 15 | - | $3,011 | $138,195 | 2 | Sony Pictures Releasing | false | false |
| 15 | 11 | Doubt | $44,586 | -67.3% | 29 | -7 | $1,537 | $395,606 | 3 | Walt Disney Pictures | false | false |
| 16 | 10 | Beverly Hills Chihuahua | $40,077 | -72.8% | 65 | +1 | $616 | $215,433 | 2 | Walt Disney Pictures | false | false |
| 17 | 15 | Marley & Me | $21,487 | -58.7% | 84 | -24 | $255 | $6,242,008 | 9 | 20th Century Fox International | false | false |
| 18 | 16 | Veronica | $17,844 | -45.1% | 41 | -70 | $435 | $277,941 | 3 | Europa Filmes | false | false |
| 19 | 14 | Revolutionary Road | $17,367 | -66.9% | 39 | -21 | $445 | $721,433 | 4 | Paramount Pictures International | false | false |
| 20 | 23 | Deep Sea | $13,946 | -7% | 1 | - | $13,946 | $303,612 | 6 | IMAX | false | false |
| 21 | 17 | The Dark Knight | $11,496 | -64.5% | 1 | -72 | $11,496 | $20,122,313 | 32 | Warner Bros. | false | false |
| 22 | 18 | Bolt | $9,056 | -69.7% | 92 | -46 | $98 | $4,088,495 | 8 | Walt Disney Pictures | false | false |
| 23 | 22 | Changeling | $8,283 | -45.2% | 35 | -5 | $236 | $1,017,791 | 7 | Universal Pictures International (UPI) | false | false |
| 24 | - | Frozen River | $7,655 | - | 6 | - | $1,275 | $7,655 | 1 | Sony Pictures Releasing | true | false |
| 25 | 21 | Madagascar: Escape 2 Africa | $5,925 | -66.2% | 31 | -30 | $191 | $16,503,755 | 11 | Paramount Pictures International | false | false |
| 26 | 20 | Australia | $4,485 | -75.5% | 23 | -40 | $195 | $1,157,697 | 5 | 20th Century Fox International | false | false |
| 27 | 29 | The Happy Cricket and the Giant Bugs | $3,473 | -60.5% | 52 | -20 | $66 | $561,163 | 7 | 20th Century Fox International | false | false |
| 28 | 25 | The Day the Earth Stood Still | $3,080 | -78.3% | 13 | +9 | $236 | $5,201,865 | 7 | 20th Century Fox International | false | false |
| 29 | 34 | Burn After Reading | $2,649 | +3.2% | 13 | - | $203 | $2,047,071 | 13 | Universal Pictures International (UPI) | false | false |
| 30 | 28 | Seven Pounds | $2,571 | -75.7% | 14 | -16 | $183 | $4,633,283 | 9 | Sony Pictures Releasing | false | false |
| 31 | 37 | The Boy in the Striped Pajamas | $1,767 | +4.9% | 6 | -1 | $294 | $260,135 | 11 | Walt Disney Pictures | false | false |
| 32 | 31 | The Tale of Despereaux | $1,627 | -77.9% | 38 | -15 | $42 | $765,835 | 6 | Universal Pictures International (UPI) | false | false |
| 33 | 30 | Four Christmases | $1,108 | -85.6% | 17 | -37 | $65 | $941,993 | 5 | PlayArte Pictures | false | false |
| 34 | - | Once Upon a Time in Rio | $339 | - | 2 | - | $169 | $486,970 | 14 | Walt Disney Pictures | false | false |
| 35 | 42 | Inkheart | $289 | -71.9% | 3 | -6 | $96 | $1,237,400 | 9 | PlayArte Pictures | false | false |
| 36 | 40 | Quarantine | $229 | -79% | 6 | -6 | $38 | $390,326 | 6 | Sony Pictures Releasing | false | false |
| 37 | 62 | Fly Me to the Moon 3D | $110 | - | 3 | - | $36 | $1,683,313 | 20 | PlayArte Pictures | false | false |
| 38 | 43 | Romance | $102 | -88.6% | 2 | -1 | $51 | $873,240 | 15 | Walt Disney Pictures | false | false |
