| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Curious Case of Benjamin Button | $531,268 | -15.9% | 90 | +1 | $5,902 | $2,184,362 | 3 | Warner Bros. | false | false |
| 2 | - | Bolt | $409,227 | - | 125 | - | $3,273 | $486,527 | 1 | Walt Disney Pictures | true | false |
| 3 | 3 | Spy of Orange | $356,800 | -17.9% | 108 | +1 | $3,303 | $860,073 | 2 | A-Film Distribution | false | false |
| 4 | 2 | Valkyrie | $314,515 | -32.9% | 98 | +1 | $3,209 | $2,795,840 | 4 | Warner Bros. | false | false |
| 5 | - | Slumdog Millionaire | $309,258 | - | 32 | - | $9,664 | $386,909 | 1 | Cinéart | true | false |
| 6 | - | Recep Ivedik 2 | $221,331 | - | - | - | - | $221,331 | 1 | N/A | true | false |
| 7 | 4 | Yes Man | $179,537 | -33.1% | 82 | -2 | $2,189 | $3,302,138 | 6 | Warner Bros. | false | false |
| 8 | - | Friday the 13th | $168,129 | - | 34 | - | $4,944 | $168,129 | 1 | Universal Pictures International (UPI) | true | false |
| 9 | - | New in Town | $167,582 | - | 52 | - | $3,222 | $245,579 | 1 | RCV Film Distribution | true | false |
| 10 | - | Transporter 3 | $106,058 | - | 35 | - | $3,030 | $138,074 | 1 | RCV Film Distribution | true | false |
| 11 | 5 | The Tale of Despereaux | $99,227 | -59% | 70 | +1 | $1,417 | $429,865 | 2 | Universal Pictures International (UPI) | false | false |
| 12 | - | Frogs and Toads | $98,960 | - | 103 | - | $960 | $127,015 | 1 | A-Film Distribution | true | false |
| 13 | - | The Pink Panther 2 | $97,318 | - | 41 | - | $2,373 | $97,318 | 1 | Sony Pictures Releasing | true | false |
| 14 | 6 | Australia | $94,438 | -37.1% | 69 | -18 | $1,368 | $4,025,166 | 9 | Warner Bros. | false | false |
| 15 | 7 | Winter in Wartime | $82,229 | -40.9% | 77 | -19 | $1,067 | $7,260,111 | 12 | Benelux Film Distributors | false | false |
| 16 | 8 | Make It Happen | $78,043 | -31% | 15 | - | $5,202 | $222,916 | 2 | Benelux Film Distributors | false | false |
| 17 | 9 | Gomorrah | $75,165 | -31.4% | 24 | - | $3,131 | $388,552 | 3 | Cinemien | false | false |
| 18 | - | The Wrestler | $60,202 | - | 26 | - | $2,315 | $64,455 | 1 | Wild Bunch Distribution | true | false |
| 19 | 10 | Revolutionary Road | $54,420 | -45.6% | 28 | -14 | $1,943 | $613,532 | 4 | Universal Pictures International (UPI) | false | false |
| 20 | 12 | Doubt | $38,291 | -46.1% | 32 | -1 | $1,196 | $140,453 | 2 | Walt Disney Pictures | false | false |
| 21 | 11 | Madagascar: Escape 2 Africa | $35,082 | -60.8% | 87 | -21 | $403 | $8,082,379 | 13 | Universal Pictures International (UPI) | false | false |
| 22 | 13 | Milk | $31,274 | -40.9% | 11 | -10 | $2,843 | $243,449 | 4 | A-Film Distribution | false | false |
| 23 | - | The Secret of Moonacre | $29,148 | - | 40 | - | $728 | $29,148 | 1 | RCV Film Distribution | true | false |
| 24 | 14 | Seven Pounds | $17,273 | -67.2% | 11 | -24 | $1,570 | $780,597 | 5 | Sony Pictures Releasing | false | false |
| 25 | - | City of Ember | $12,068 | - | 18 | - | $670 | $16,879 | 1 | Independent Films | true | false |
| 26 | - | Frost/Nixon | $301 | - | 1 | - | $301 | $145,778 | 5 | Universal Pictures International (UPI) | false | false |
