| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Valkyrie | $628,528 | - | 70 | - | $8,978 | $646,270 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Revolutionary Road | $243,802 | -26.2% | 43 | - | $5,669 | $651,580 | 2 | Universal Pictures International (UPI) | false | false |
| 3 | 2 | Yes Man | $219,001 | -15.2% | 55 | -5 | $3,981 | $1,975,133 | 5 | Warner Bros. | false | false |
| 4 | 6 | Slumdog Millionaire | $183,701 | <0.1% | 22 | +4 | $8,350 | $616,757 | 3 | Cinéart | false | false |
| 5 | 5 | Twilight | $165,898 | -11.1% | 54 | - | $3,072 | $3,051,985 | 10 | Belga Films | false | false |
| 6 | 4 | De l'autre côté du lit | $162,886 | -15.6% | 28 | - | $5,817 | $994,502 | 4 | Belga Films | false | false |
| 7 | 3 | Seven Pounds | $156,602 | -31% | 30 | - | $5,220 | $744,779 | 3 | Sony Pictures Releasing | false | false |
| 8 | 7 | Madagascar: Escape 2 Africa | $127,407 | -21.1% | 88 | -12 | $1,447 | $6,673,508 | 9 | Universal Pictures International (UPI) | false | false |
| 9 | - | The Women | $74,553 | - | 17 | - | $4,385 | $115,826 | 1 | Belga Films | true | false |
| 10 | - | Dirty Mind | $69,723 | - | 18 | - | $3,873 | $71,260 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 11 | 9 | Loft | $61,027 | -19.2% | 35 | +5 | $1,743 | $9,305,725 | 15 | Independent Films | false | false |
| 12 | 8 | Australia | $60,528 | -26.6% | 50 | -20 | $1,210 | $1,824,453 | 7 | 20th Century Fox International | false | false |
| 13 | 12 | Burn After Reading | $45,725 | -26.4% | 22 | -10 | $2,078 | $1,582,797 | 8 | Universal Pictures International (UPI) | false | false |
| 14 | 16 | The Flight Before Christmas | $40,304 | -2.7% | 31 | - | $1,300 | $669,778 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 15 | 11 | Beauties at War | $40,095 | -38.5% | 17 | -1 | $2,358 | $251,377 | 3 | Belga Films | false | false |
| 16 | 10 | The Duchess | $39,100 | -44.5% | 24 | -5 | $1,629 | $435,372 | 4 | Cinéart | false | false |
| 17 | 13 | Bedtime Stories | $34,581 | -35% | 35 | -10 | $988 | $1,016,313 | 6 | Walt Disney Pictures | false | false |
| 18 | 20 | Trouble at Timpetill | $30,461 | +2.7% | 14 | - | $2,175 | $543,576 | 7 | Alternative Films | false | false |
| 19 | 19 | Piet Piraat en het zwaard van Zilvertand | $26,806 | -10% | 28 | -1 | $957 | $622,501 | 8 | Kinepolis Film Distribution (KFD) | false | false |
| 20 | 14 | Special Correspondents | $25,360 | -45.2% | 15 | -1 | $1,690 | $80,297 | 2 | Victory Productions | false | false |
| 21 | 17 | Eden Lake | $24,523 | -39.7% | 7 | - | $3,503 | $71,657 | 2 | Benelux Film Distributors | false | false |
| 22 | 15 | Transporter 3 | $23,067 | -46.3% | 24 | -1 | $961 | $1,387,162 | 8 | Belga Films | false | false |
| 23 | 22 | Two Lovers | $18,783 | -25.7% | 10 | -3 | $1,878 | $470,570 | 6 | Cinéart | false | false |
| 24 | 24 | Private Lessons | $16,502 | -27.4% | 8 | -1 | $2,062 | $54,493 | 2 | Cinéart | false | false |
| 25 | 18 | Frost/Nixon | $15,653 | -48.1% | 12 | -7 | $1,304 | $124,607 | 3 | Universal Pictures International (UPI) | false | false |
| 26 | 23 | Afterwards | $13,462 | -44.1% | 11 | - | $1,223 | $85,950 | 3 | Victory Productions | false | false |
| 27 | 26 | The Heir Apparent: Largo Winch | $12,849 | -26.7% | 16 | - | $803 | $605,431 | 7 | Cinéart | false | false |
| 28 | 21 | The Day the Earth Stood Still | $12,664 | -54.2% | 10 | -10 | $1,266 | $2,115,475 | 8 | 20th Century Fox International | false | false |
| 29 | - | Diamond 13 | $12,487 | - | 9 | - | $1,387 | $12,487 | 1 | Les Films de l'Elysée | true | false |
| 30 | 27 | Il Divo | $10,191 | -34.6% | 8 | -1 | $1,273 | $71,725 | 3 | ABC Distribution | false | false |
| 31 | 25 | Elite Squad | $9,442 | -52.9% | 9 | - | $1,049 | $51,266 | 2 | Benelux Film Distributors | false | false |
| 32 | - | The Class | $8,753 | - | 11 | - | $795 | $890,543 | 18 | Cinéart | false | false |
| 33 | 34 | Blinker en de blixvaten | $8,653 | -13.3% | 14 | -5 | $618 | $289,762 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 34 | 28 | Winter in Wartime | $8,560 | -44% | 14 | - | $611 | $355,789 | 9 | Benelux Film Distributors | false | false |
| 35 | 35 | Quantum of Solace | $7,982 | -7.4% | 1 | -2 | $7,982 | $4,741,941 | 13 | Sony Pictures Releasing | false | false |
| 36 | 32 | Pride and Glory | $7,834 | -32.6% | 2 | -1 | $3,917 | $228,773 | 9 | Kinepolis Film Distribution (KFD) | false | false |
| 37 | 33 | Changeling | $6,597 | -35.9% | 8 | -2 | $824 | $1,048,062 | 12 | Universal Pictures International (UPI) | false | false |
| 38 | 37 | High School Musical 3: Senior Year | $6,550 | -7.2% | 4 | -2 | $1,637 | $2,834,261 | 14 | Walt Disney Pictures | false | false |
| 39 | 29 | Welcome to the Sticks | $6,063 | -56.2% | 6 | +1 | $1,010 | $10,704,001 | 49 | Alternative Films | false | false |
| 40 | 31 | A Man and His Dog | $5,990 | -50.6% | 9 | - | $665 | $25,089 | 2 | Les Films de l'Elysée | false | false |
| 41 | 30 | The Broken | $4,514 | -66.4% | 4 | -1 | $1,128 | $107,759 | 3 | Paradiso Entertainment | false | false |
| 42 | 39 | Stella | $4,501 | -21.9% | 6 | - | $750 | $20,045 | 3 | Benelux Film Distributors | false | false |
| 43 | 36 | Appaloosa | $4,167 | -42.2% | 4 | - | $1,041 | $91,441 | 4 | Paradiso Entertainment | false | false |
| 44 | - | O'Horten | $4,034 | - | 4 | - | $1,008 | $4,730 | 1 | Centre national du cinéma et de l'image animée (CNC) | true | false |
| 45 | - | The Baader Meinhof Complex | $3,845 | - | 6 | - | $640 | $55,132 | 1 | A-Film Distribution | true | false |
| 46 | 40 | Wild Child | $3,788 | -30.1% | 6 | -1 | $631 | $213,007 | 6 | Universal Pictures International (UPI) | false | false |
| 47 | 42 | Christmas in Paris | $2,750 | -28.1% | 3 | -6 | $916 | $228,787 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 48 | 41 | Anubis en het Pad der 7 Zonden | $2,657 | -30.8% | 3 | +1 | $885 | $1,509,366 | 16 | Kinepolis Film Distribution (KFD) | false | false |
| 49 | 43 | Modern Life | $1,590 | -58.3% | 2 | - | $795 | $55,651 | 13 | Benelux Film Distributors | false | false |
| 50 | 47 | Moscow, Belgium | $1,185 | +54.5% | 4 | +2 | $296 | $1,885,401 | 53 | Kinepolis Film Distribution (KFD) | false | false |
| 51 | 49 | Home | $934 | +100.9% | 2 | - | $467 | $56,968 | 12 | Benelux Film Distributors | false | false |
| 52 | 51 | Elegy | $659 | +102.1% | 3 | -5 | $219 | $192,722 | 15 | Kinepolis Film Distribution (KFD) | false | false |
| 53 | 46 | Hunger | $611 | -20.8% | 4 | - | $152 | $41,185 | 12 | Paradiso Entertainment | false | false |
| 54 | 53 | The Wave | $501 | +475.9% | 2 | +1 | $250 | $58,173 | 15 | Paradiso Entertainment | false | false |
| 55 | 52 | A Pain in the Ass | $59 | -77.4% | 1 | - | $59 | $78,203 | 8 | Benelux Film Distributors | false | false |
| 56 | - | SOS: Summer of Suspense | $18 | - | 1 | - | $18 | $18 | 1 | Jekino | true | false |
