| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Yes Man | $311,673 | - | 20 | - | $15,583 | $311,673 | 1 | N/A | true | false |
| 2 | - | Slumdog Millionaire | $306,273 | - | 23 | - | $13,316 | $306,273 | 1 | Gulf Film | true | false |
| 3 | - | Underworld: Rise of the Lycans | $242,547 | - | 19 | - | $12,765 | $242,547 | 1 | N/A | true | false |
| 4 | - | Sorry to Disturb | $186,412 | - | 20 | - | $9,320 | $186,412 | 1 | N/A | true | false |
| 5 | 1 | Valkyrie | $91,067 | -70.5% | 17 | -3 | $5,356 | $488,342 | 2 | N/A | false | false |
| 6 | - | Revolutionary Road | $58,019 | - | 19 | - | $3,053 | $58,019 | 1 | N/A | true | false |
| 7 | 2 | Bride Wars | $51,086 | -67% | 6 | -13 | $8,514 | $274,594 | 2 | N/A | false | false |
| 8 | 6 | Bedtime Stories | $22,690 | -41.4% | 2 | -3 | $11,345 | $568,682 | 5 | N/A | false | false |
| 9 | 3 | Mutant Chronicles | $14,464 | -88.2% | 13 | -7 | $1,112 | $174,054 | 2 | N/A | false | false |
| 10 | 5 | Changeling | $9,998 | -77.1% | 3 | -9 | $3,332 | $265,122 | 3 | N/A | false | false |
| 11 | 12 | Madagascar: Escape 2 Africa | $9,045 | -25% | 3 | - | $3,015 | $1,870,237 | 9 | N/A | false | false |
| 12 | 4 | Harold & Kumar Escape from Guantanamo Bay | $8,253 | -90.3% | 6 | -10 | $1,375 | $124,338 | 2 | N/A | false | false |
| 13 | 16 | Bolt | $7,363 | +2.5% | 1 | -1 | $7,363 | $458,832 | 8 | N/A | false | false |
| 14 | 7 | City of Ember | $7,168 | -78.8% | 3 | -12 | $2,389 | $203,343 | 3 | N/A | false | false |
| 15 | 14 | Twilight | $3,937 | -62.7% | 2 | -7 | $1,968 | $1,233,027 | 8 | N/A | false | false |
| 16 | 17 | The Women | $2,492 | -52.4% | 2 | - | $1,246 | $180,941 | 4 | N/A | false | false |
| 17 | - | Julia | $1,338 | - | 3 | - | $446 | $1,338 | 1 | N/A | true | false |
| 18 | 11 | Australia | $907 | -92.6% | 1 | -2 | $907 | $310,230 | 5 | N/A | false | false |
| 19 | 19 | Traitor | $896 | -80.7% | 2 | - | $448 | $421,437 | 5 | N/A | false | false |
| 20 | 22 | Righteous Kill | $705 | -61% | 1 | -1 | $705 | $327,892 | 6 | N/A | false | false |
