| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Madagascar: Escape 2 Africa | $1,113,084 | -9.2% | 138 | -5 | $8,065 | $9,599,522 | 5 | Universal Pictures International (UPI) | false | false |
| 2 | 2 | Australia | $892,806 | -7.1% | 106 | +6 | $8,422 | $2,326,165 | 2 | 20th Century Fox International | false | false |
| 3 | 3 | Bedtime Stories | $300,993 | +12.2% | 60 | +2 | $5,016 | $728,578 | 2 | Walt Disney Pictures | false | false |
| 4 | 4 | Quantum of Solace | $142,346 | -10.3% | 47 | +1 | $3,028 | $10,508,458 | 9 | Walt Disney Pictures | false | false |
| 5 | 6 | Vicky Cristina Barcelona | $129,988 | +0.2% | 20 | +1 | $6,499 | $1,862,094 | 13 | Frenetic Films | false | false |
| 6 | 5 | Natale a Rio | $118,820 | -24.2% | 17 | +4 | $6,989 | $539,575 | 3 | - | false | false |
| 7 | 7 | Burn After Reading | $117,839 | -3.6% | 22 | +2 | $5,356 | $2,579,592 | 16 | Ascot Elite Entertainment Group | false | false |
| 8 | 10 | Buddenbrooks | $115,265 | +3% | 14 | +2 | $8,233 | $323,647 | 2 | Warner Bros. | false | false |
| 9 | 8 | The Day the Earth Stood Still | $112,776 | -1.5% | 30 | -5 | $3,759 | $921,849 | 4 | 20th Century Fox International | false | false |
| 10 | 9 | 1½ Knights - In Search of the Ravishing Princess Herzelinde | $99,972 | -11.1% | 28 | - | $3,570 | $435,993 | 3 | Warner Bros. | false | false |
| 11 | 11 | Wild Child | $71,381 | +28.9% | 33 | - | $2,163 | $249,945 | 3 | Universal Pictures International (UPI) | false | false |
| 12 | - | The Heir Apparent: Largo Winch | $58,881 | - | 15 | - | $3,925 | $279,188 | 3 | Frenetic Films | false | false |
| 13 | - | Welcome to the Sticks | $53,197 | - | 9 | - | $5,910 | $8,914,390 | 45 | Pathé | false | false |
| 14 | 17 | Body of Lies | $50,291 | +301.8% | 16 | +10 | $3,143 | $1,211,246 | 7 | Warner Bros. | false | false |
| 15 | 18 | The Spirit | $46,775 | +997% | 40 | +39 | $1,169 | $52,375 | 2 | Walt Disney Pictures | false | false |
| 16 | 14 | Inkheart | $45,053 | +73% | 27 | +3 | $1,668 | $240,780 | 4 | Warner Bros. | false | false |
| 17 | - | Transporter 3 | $44,459 | - | 5 | - | $8,891 | $44,459 | 1 | JMH Distribution | true | false |
| 18 | - | Il cosmo sul comò | $43,041 | - | 11 | - | $3,912 | $208,891 | 3 | - | false | false |
| 19 | 12 | Four Christmases | $39,727 | -7% | 15 | -2 | $2,648 | $429,179 | 5 | Warner Bros. | false | false |
| 20 | 13 | Changeling | $35,705 | -5.5% | 17 | -1 | $2,100 | $772,556 | 8 | Universal Pictures International (UPI) | false | false |
| 21 | 15 | Mamma Mia! | $16,050 | +10.3% | 13 | -1 | $1,234 | $8,883,724 | 25 | Universal Pictures International (UPI) | false | false |
| 22 | - | Fly Me to the Moon 3D | $8,983 | - | 2 | - | $4,491 | $63,224 | 10 | N/A | false | false |
| 23 | 19 | Kung Fu Panda | $607 | -54.4% | 2 | - | $303 | $5,009,099 | 27 | Universal Pictures International (UPI) | false | false |
