| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Day the Earth Stood Still | $613,595 | - | 48 | - | $12,783 | $613,595 | 1 | N/A | true | false |
| 2 | 1 | Bolt | $296,977 | -49.4% | 51 | - | $5,823 | $1,226,733 | 2 | N/A | false | false |
| 3 | - | Twilight | $286,178 | - | 35 | - | $8,176 | $295,352 | - | N/A | - | false |
| 4 | 2 | Four Christmases | $35,500 | -68.8% | 20 | -6 | $1,775 | $427,260 | 3 | N/A | false | false |
| 5 | 6 | Cape No. 7 | $29,228 | -51.7% | 8 | -4 | $3,653 | $237,155 | 3 | N/A | false | false |
| 6 | 3 | Madagascar: Escape 2 Africa | $24,629 | -73.2% | 21 | -6 | $1,172 | $2,705,914 | 5 | N/A | false | false |
| 7 | - | Igor | $22,969 | - | 7 | - | $3,281 | $22,969 | 1 | N/A | true | false |
| 8 | - | Nick and Norah's Infinite Playlist | $22,016 | - | 8 | - | $2,752 | $29,755 | 1 | N/A | true | false |
| 9 | 9 | Zack and Miri Make a Porno | $19,061 | -54.4% | 4 | - | $4,765 | $91,585 | 2 | N/A | false | false |
| 10 | 5 | Body of Lies | $18,005 | -73.9% | 16 | -11 | $1,125 | $701,526 | 4 | N/A | false | false |
| 11 | 4 | Quarantine | $15,636 | -81.8% | 17 | -4 | $919 | $353,406 | 3 | N/A | false | false |
| 12 | 7 | Beast Stalker | $15,270 | -72.8% | 11 | - | $1,388 | $97,146 | 2 | N/A | false | false |
| 13 | 11 | Sex Drive | $12,576 | -54.2% | 7 | - | $1,796 | $55,273 | 2 | N/A | false | false |
| 14 | 12 | Quantum of Solace | $7,335 | -73.2% | 6 | -6 | $1,222 | $2,477,339 | 6 | N/A | false | false |
| 15 | 10 | Wild Child | $6,809 | -77.9% | 7 | -8 | $972 | $173,235 | 3 | N/A | false | false |
| 16 | 8 | City of Ember | $6,664 | -86.9% | 10 | -6 | $666 | $235,711 | 3 | N/A | false | false |
| 17 | - | The Visitor | $5,109 | - | 1 | - | $5,109 | $5,109 | 1 | N/A | true | false |
| 18 | - | Angus, Thongs and Perfect Snogging | $3,533 | - | 12 | - | $294 | $3,533 | - | N/A | - | false |
| 19 | 13 | Beverly Hills Chihuahua | $3,400 | -86.4% | 9 | -17 | $377 | $537,237 | 4 | N/A | false | false |
| 20 | 14 | KM 31: Kilometre 31 | $2,882 | -86.5% | 1 | -3 | $2,882 | $69,461 | 3 | N/A | false | false |
| 21 | 17 | The Secret Life of Bees | $1,804 | -57% | 1 | - | $1,804 | $10,925 | 2 | N/A | false | false |
| 22 | 19 | Sing to the Dawn | $150 | -70.3% | 2 | -1 | $75 | $180,173 | 7 | N/A | false | false |
