| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Quantum of Solace | $859,175 | -35.9% | 406 | +2 | $2,116 | $5,787,955 | 3 | Sony Pictures Releasing | false | false |
| 2 | 2 | Vicky Cristina Barcelona | $397,018 | -21.2% | 85 | - | $4,670 | $1,262,579 | 2 | Imagem Filmes | false | false |
| 3 | - | Max Payne | $314,506 | - | 107 | - | $2,939 | $380,542 | 1 | 20th Century Fox International | true | false |
| 4 | - | The Strangers | $300,029 | - | 10 | - | $30,002 | $354,989 | 1 | Paris Filmes | true | false |
| 5 | 3 | High School Musical 3: Senior Year | $269,123 | -24.8% | 214 | -5 | $1,257 | $5,108,572 | 5 | Walt Disney Pictures | false | false |
| 6 | 6 | Romance | $175,618 | -5.5% | 88 | - | $1,995 | $447,544 | 2 | Walt Disney Pictures | false | false |
| 7 | - | The Duchess | $144,039 | - | 40 | - | $3,600 | $182,503 | 1 | Paramount Pictures International | true | false |
| 8 | - | Once Upon a Time in Rio | $141,544 | - | 60 | - | $2,359 | $157,432 | 1 | Walt Disney Pictures | true | false |
| 9 | 4 | Saw V | $139,259 | -47.1% | 195 | -9 | $714 | $2,307,739 | 4 | Walt Disney Pictures | false | false |
| 10 | 5 | REC | $102,479 | -54.1% | 104 | -2 | $985 | $443,710 | 2 | California Filmes | false | false |
| 11 | 7 | Last Stop 174 | $83,027 | -32.7% | 120 | -8 | $691 | $1,479,085 | 5 | Paramount Pictures International | false | false |
| 12 | 8 | Dan in Real Life | $55,801 | -18% | 46 | +3 | $1,213 | $633,751 | 4 | Europa Filmes | false | false |
| 13 | 15 | Fly Me to the Moon 3D | $39,844 | +11.9% | 131 | -5 | $304 | $1,641,028 | 7 | PlayArte Pictures | false | false |
| 14 | 13 | Blindness | $37,175 | -19.7% | 70 | -12 | $531 | $3,388,578 | 11 | 20th Century Fox International | false | false |
| 15 | 9 | My Best Friend's Girl | $36,561 | -42.1% | 77 | -12 | $474 | $1,875,002 | 6 | Imagem Filmes | false | false |
| 16 | 14 | A Guerra dos Rocha | $33,987 | -20.2% | 73 | -7 | $465 | $988,463 | 7 | 20th Century Fox International | false | false |
| 17 | - | Scar | $33,311 | - | 23 | - | $1,448 | $66,395 | 1 | PlayArte Pictures | true | false |
| 18 | 10 | Traitor | $25,067 | -58.8% | 34 | -7 | $737 | $119,099 | 2 | PlayArte Pictures | false | false |
| 19 | - | December | $23,422 | - | 18 | - | $1,301 | $27,060 | 1 | Europa Filmes | true | false |
| 20 | 12 | Righteous Kill | $19,382 | -58.4% | 40 | -40 | $484 | $2,732,314 | 7 | California Filmes | false | false |
| 21 | 11 | Amazon Jack | $18,085 | -70% | 41 | - | $441 | $155,245 | 2 | Focus Film | false | false |
| 22 | 17 | Disaster Movie | $17,560 | -31.2% | 54 | -16 | $325 | $3,074,975 | 8 | Imagem Filmes | false | false |
| 23 | 18 | Mirrors | $14,335 | -26.7% | 30 | -5 | $477 | $679,094 | 6 | 20th Century Fox International | false | false |
| 24 | 16 | The Children's Orchestra | $11,760 | -60.2% | 25 | -22 | $470 | $130,011 | 3 | Paramount Pictures International | false | false |
| 25 | 21 | RocknRolla | $10,943 | -23.8% | 24 | -2 | $455 | $241,212 | 4 | Warner Bros. | false | false |
| 26 | 20 | Death Race | $9,975 | -32.1% | 44 | -14 | $226 | $517,806 | 6 | Paramount Pictures International | false | false |
| 27 | 22 | Golden Oldies | $9,540 | -29.6% | 22 | -29 | $433 | $1,738,542 | 10 | 20th Century Fox International | false | false |
| 28 | 25 | Lorna's Silence | $9,104 | +11.6% | 9 | +5 | $1,011 | $41,042 | 3 | Imovision | false | false |
| 29 | 58 | Step Brothers | $9,005 | +1,984.5% | 16 | +10 | $562 | $183,893 | 5 | Sony Pictures Releasing | false | false |
| 30 | 19 | Mamma Mia! | $8,975 | -45.8% | 17 | -16 | $527 | $3,178,900 | 11 | Paramount Pictures International | false | false |
| 31 | 24 | Bezerra De Menezes: The Diary of a Spirit | $7,986 | -18.8% | 36 | -11 | $221 | $1,899,780 | 13 | 20th Century Fox International | false | false |
| 32 | 29 | Nights in Rodanthe | $6,286 | -3.1% | 20 | +5 | $314 | $1,400,986 | 8 | Warner Bros. | false | false |
| 33 | 26 | Journey to the Center of the Earth | $6,257 | -18.2% | 7 | -8 | $893 | $5,031,533 | 20 | PlayArte Pictures | false | false |
| 34 | 36 | The House Bunny | $4,238 | +13.9% | 7 | -3 | $605 | $297,596 | 7 | Sony Pictures Releasing | false | false |
| 35 | - | The Neighbor | $3,633 | - | 2 | - | $1,816 | $3,633 | 1 | N/A | true | false |
| 36 | 35 | Linha de Passe | $2,929 | -22% | 11 | -10 | $266 | $645,290 | 12 | Paramount Pictures International | false | false |
| 37 | 42 | Babylon A.D. | $2,614 | +41.8% | 12 | -2 | $217 | $1,165,034 | 10 | 20th Century Fox International | false | false |
| 38 | 30 | Once Upon a Time... | $2,133 | -58.7% | 10 | -7 | $213 | $2,810,514 | 18 | Sony Pictures Releasing | false | false |
| 39 | 39 | Panair do Brasil | $2,105 | -12.5% | 4 | +1 | $526 | $11,033 | 3 | Downtown Filmes | false | false |
| 40 | - | A Thousand Years of Good Prayers | $1,638 | - | 2 | - | $819 | $1,656 | 1 | Imovision | true | false |
| 41 | 43 | The Mummy: Tomb of the Dragon Emperor | $1,579 | -14.3% | 4 | - | $394 | $10,899,301 | 17 | Paramount Pictures International | false | false |
| 42 | 48 | The Warrior Didi and the Ninja Lili | $1,553 | +35.3% | 6 | -5 | $258 | $1,210,995 | 23 | Walt Disney Pictures | false | false |
| 43 | 54 | Eagle Eye | $856 | +46.1% | 8 | +2 | $107 | $1,190,433 | 9 | Paramount Pictures International | false | false |
| 44 | - | The Princess of Nebraska | $636 | - | 2 | - | $318 | $649 | 1 | Imovision | true | false |
| 45 | 32 | Under the Same Moon | $603 | -86.5% | 3 | -3 | $201 | $7,533 | 2 | 20th Century Fox International | false | false |
| 46 | 34 | Leonera | $469 | -88.4% | 4 | -1 | $117 | $25,475 | 3 | Walt Disney Pictures | false | false |
| 47 | 47 | You Don't Mess with the Zohan | $380 | -68.6% | 3 | -3 | $126 | $3,824,585 | 15 | Sony Pictures Releasing | false | false |
| 48 | 70 | WALL·E | $281 | +172.8% | 8 | - | $35 | $6,304,890 | 22 | Walt Disney Pictures | false | false |
| 49 | 57 | Standard Operating Procedure | $32 | -92.8% | 1 | -2 | $32 | $5,731 | 4 | Sony Pictures Releasing | false | false |
