| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Quantum of Solace | $3,978,050 | - | 491 | - | $8,101 | $3,978,050 | 1 | Sony Pictures Releasing | true | false |
| 2 | 1 | High School Musical 3: Senior Year | $2,559,010 | -50.7% | 487 | -6 | $5,254 | $8,862,587 | 2 | Walt Disney Pictures | false | false |
| 3 | 3 | Welcome to the Sticks | $820,851 | -36.1% | 312 | -13 | $2,630 | $2,417,712 | 2 | Medusa Distribuzione | false | false |
| 4 | 2 | WALL·E | $702,734 | -58% | 313 | -109 | $2,245 | $9,898,219 | 4 | Walt Disney Pictures | false | false |
| 5 | - | The Burning Plain | $672,020 | - | 216 | - | $3,111 | $682,953 | 1 | Medusa Distribuzione | true | false |
| 6 | 4 | Tropic Thunder | $507,598 | -57.6% | 192 | -94 | $2,643 | $4,146,195 | 3 | Universal Pictures International (UPI) | false | false |
| 7 | 5 | Vicky Cristina Barcelona | $450,021 | -54.1% | 162 | -100 | $2,777 | $6,696,542 | 4 | Medusa Distribuzione | false | false |
| 8 | 8 | Mamma Mia! | $392,508 | -44.6% | 117 | -49 | $3,354 | $10,456,398 | 6 | United International Pictures | false | false |
| 9 | 6 | Pride and Glory | $375,392 | -57.1% | 216 | -29 | $1,737 | $1,536,023 | 2 | Eagle Pictures | false | false |
| 10 | - | Un gioco da ragazze | $318,754 | - | 173 | - | $1,842 | $318,754 | 1 | 01 Distribution | true | false |
| 11 | - | Frontier(s) | $315,997 | - | 112 | - | $2,821 | $336,357 | 1 | Moviemax | true | false |
| 12 | 11 | We Can Do That | $282,449 | -12.8% | 97 | +7 | $2,911 | $715,688 | 2 | Warner Bros. | false | false |
| 13 | 7 | Babylon A.D. | $253,880 | -70.6% | 117 | -95 | $2,169 | $3,185,644 | 3 | Moviemax | false | false |
| 14 | 10 | The Man Who Loves | $179,754 | -52.6% | 99 | -53 | $1,815 | $1,510,935 | 3 | Medusa Distribuzione | false | false |
| 15 | 9 | The Past Is a Foreign Land | $163,480 | -58.9% | 116 | -63 | $1,409 | $706,358 | 2 | 01 Distribution | false | false |
| 16 | 14 | The Class | $97,103 | -35.8% | 45 | -9 | $2,157 | $1,696,443 | 5 | Mikado Film | false | false |
| 17 | 12 | No Problem | $72,816 | -60.9% | 29 | -33 | $2,510 | $4,773,594 | 5 | Medusa Distribuzione | false | false |
| 18 | 13 | The Baader Meinhof Complex | $52,452 | -67.4% | 45 | -74 | $1,165 | $275,751 | 2 | BIM Distribuzione | false | false |
| 19 | - | Trick or Treaters | $50,233 | - | 74 | - | $678 | $50,233 | 1 | BIM Distribuzione | true | false |
| 20 | 18 | Mid-August Lunch | $41,134 | -17.8% | 18 | +1 | $2,285 | $2,499,469 | 10 | Fandango | false | false |
| 21 | 16 | Burn After Reading | $36,483 | -45.2% | 15 | -1 | $2,432 | $7,621,789 | 8 | Medusa Distribuzione | false | false |
| 22 | - | One Day in a Life | $19,184 | - | 12 | - | $1,598 | $19,184 | 1 | Ripley's Film | true | false |
| 23 | 21 | Bonneville | $18,765 | -24.6% | 14 | +1 | $1,340 | $326,403 | 4 | Teodora Film | false | false |
| 24 | 23 | Giovanna's Father | $11,717 | -38% | 6 | -5 | $1,952 | $4,565,100 | 9 | Medusa Distribuzione | false | false |
| 25 | 20 | Lecture 21 | $10,384 | -59.9% | 7 | -6 | $1,483 | $303,601 | 4 | 01 Distribution | false | false |
| 26 | 19 | Donkey Xote | $9,323 | -70.6% | 35 | -34 | $266 | $45,189 | 2 | N/A | false | false |
| 27 | 22 | Kung Fu Panda | $8,914 | -58.9% | 16 | -2 | $557 | $21,518,305 | 11 | Universal Pictures International (UPI) | false | false |
| 28 | 34 | Paris | $8,754 | +70.5% | 7 | +3 | $1,250 | $601,419 | 7 | BIM Distribuzione | false | false |
| 29 | 25 | Control | $7,824 | -45.3% | 6 | -1 | $1,304 | $68,467 | 3 | Metacinema | false | false |
| 30 | 24 | Disaster Movie | $7,224 | -61.1% | 10 | -4 | $722 | $2,946,110 | 5 | Eagle Pictures | false | false |
| 31 | 15 | Albakiara | $6,765 | -95.4% | 8 | -88 | $845 | $1,031,340 | 3 | Mikado Film | false | false |
| 32 | 29 | Lorna's Silence | $5,739 | -8% | 5 | -1 | $1,147 | $505,305 | 8 | Lucky Red | false | false |
| 33 | 35 | The Early Bird Catches the Worm | $5,095 | +21% | 1 | - | $5,095 | $1,457,898 | 37 | Medusa Distribuzione | false | false |
| 34 | 28 | Noah's Ark | $4,238 | -55.2% | 8 | -6 | $529 | $995,842 | 6 | Eagle Pictures | false | false |
| 35 | 26 | Miracle at St. Anna | $3,501 | -69.6% | 5 | -6 | $700 | $1,361,653 | 6 | 01 Distribution | false | false |
| 36 | 31 | The Mist | $2,829 | -50.5% | 3 | -4 | $943 | $1,902,311 | 5 | Lucky Red | false | false |
| 37 | 27 | The Women | $2,817 | -70.9% | 6 | -1 | $469 | $1,108,539 | 5 | BIM Distribuzione | false | false |
| 38 | - | Io non c'entro | $2,105 | - | 1 | - | $2,105 | $13,908 | 50 | Independent Films | false | false |
| 39 | - | Il pugile e la ballerina | $1,843 | - | 2 | - | $921 | $1,843 | 1 | N/A | true | false |
| 40 | 49 | Birdwatchers | $1,742 | +316.7% | 3 | - | $580 | $421,007 | 10 | 01 Distribution | false | false |
| 41 | 42 | The Wind Blows Round | $1,575 | -3.5% | 2 | - | $787 | $627,562 | 80 | Aranciafilm | false | false |
| 42 | 45 | Gravehopping | $1,565 | +77.8% | 2 | - | $782 | $30,042 | 19 | N/A | false | false |
| 43 | - | La fabbrica dei tedeschi | $1,429 | - | 2 | - | $714 | $20,844 | 9 | Istituto Luce | false | false |
| 44 | - | Into the Wild | $1,297 | - | 1 | - | $1,297 | $8,057,810 | 42 | BIM Distribuzione | false | false |
| 45 | - | The Melon Route | $1,163 | - | 1 | - | $1,163 | $1,163 | 1 | N/A | true | false |
| 46 | 33 | You Don't Mess with the Zohan | $1,154 | -79% | 4 | -7 | $288 | $3,480,821 | 6 | Sony Pictures Releasing | false | false |
| 47 | - | L'anno mille | $1,140 | - | 1 | - | $1,140 | $777,830 | 29 | Mediafilm | false | false |
| 48 | 17 | Lakeview Terrace | $1,071 | -98.1% | 10 | -21 | $107 | $81,030 | 2 | Sony Pictures Releasing | false | false |
| 49 | - | The Chronicles of Narnia: Prince Caspian | $1,046 | - | 2 | - | $523 | $11,786,123 | 13 | Walt Disney Pictures | false | false |
| 50 | 30 | Gomorrah | $987 | -84.1% | 2 | -6 | $493 | $17,630,433 | 26 | 01 Distribution | false | false |
