| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Hancock | $66,000,000 | $62,603,879 | -$3,396,121 | -5.1% | 3,965 | $107,321,000 | $103,877,446 | 1 | Sony Pictures Releasing | - |
| 2 | 2 | - | WALL·E | $33,417,000 | $32,509,203 | -$907,797 | -2.7% | 3,992 | $128,132,000 | $127,196,028 | 2 | Walt Disney Studios Motion Pictures | - |
| 3 | 3 | - | Wanted | $20,607,000 | $20,050,070 | -$556,930 | -2.7% | 3,185 | $90,775,000 | $90,186,395 | 2 | Universal Pictures | - |
| 4 | 4 | - | Get Smart | $11,125,000 | $11,109,408 | -$15,592 | -0.1% | 3,574 | $98,115,000 | $98,100,652 | 3 | Warner Bros. | - |
| 5 | 5 | - | Kung Fu Panda | $7,500,000 | $7,318,635 | -$181,365 | -2.4% | 3,347 | $193,395,000 | $193,221,867 | 5 | DreamWorks | - |
| 6 | 6 | - | The Incredible Hulk | $4,975,000 | $4,899,280 | -$75,720 | -1.5% | 3,043 | $124,917,000 | $124,841,395 | 4 | Universal Pictures | - |
| 7 | 7 | - | Indiana Jones and the Kingdom of the Crystal Skull | $3,940,000 | $3,774,807 | -$165,193 | -4.2% | 2,192 | $306,590,000 | $306,428,521 | 7 | Paramount Pictures | - |
| 8 | 8 | - | Kit Kittredge: An American Girl | $3,601,000 | $3,296,929 | -$304,071 | -8.4% | 1,843 | $6,128,000 | $5,822,544 | 3 | Picturehouse | - |
| 9 | 9 | - | Sex and the City | $2,340,000 | $2,382,438 | +$42,438 | +1.8% | 1,275 | $144,864,000 | $144,891,325 | 6 | Warner Bros. | - |
| 10 | 10 | - | You Don't Mess with the Zohan | $2,000,000 | $1,981,251 | -$18,749 | -0.9% | 1,731 | $94,780,000 | $94,773,156 | 5 | Sony Pictures Releasing | - |
| 11 | 11 | - | The Love Guru | $1,700,000 | $1,806,545 | +$106,545 | +6.3% | 2,648 | $29,331,000 | $29,427,850 | 3 | Paramount Pictures | - |
| 12 | 12 | - | Iron Man | $1,500,000 | $1,459,613 | -$40,387 | -2.7% | 1,019 | $311,758,000 | $311,708,133 | 10 | Paramount Pictures | - |
| 13 | 13 | - | The Happening | $1,450,000 | $1,438,889 | -$11,111 | -0.8% | 1,795 | $62,077,000 | $62,053,729 | 4 | Twentieth Century Fox | - |
| 14 | 14 | - | Mongol: The Rise of Genghis Khan | $883,000 | $765,120 | -$117,880 | -13.3% | 253 | $3,586,000 | $3,472,331 | 5 | Picturehouse | - |
| 15 | 15 | - | The Chronicles of Narnia: Prince Caspian | $573,000 | $551,513 | -$21,487 | -3.7% | 403 | $138,780,000 | $138,762,746 | 8 | Walt Disney Studios Motion Pictures | - |
| 16 | 16 | - | The Visitor | $355,000 | $337,105 | -$17,895 | -5% | 176 | $8,150,000 | $8,131,561 | 13 | Overture Films | - |
| 17 | 17 | - | The Strangers | $232,000 | $234,900 | +$2,900 | +1.2% | 324 | $51,990,000 | $51,991,400 | 6 | Rogue Pictures | - |
| 18 | 18 | - | What Happens in Vegas | $215,000 | $225,705 | +$10,705 | +5% | 303 | $78,746,000 | $78,755,577 | 9 | Twentieth Century Fox | - |
| 19 | 22 | +3 | Gonzo | $190,000 | $191,942 | +$1,942 | +1% | 26 | $190,000 | $191,942 | 1 | Magnolia Pictures | - |
| 20 | 26 | +6 | Baby Mama | $145,000 | $135,725 | -$9,275 | -6.4% | 234 | $59,904,000 | $59,895,435 | 11 | Universal Pictures | - |
| 21 | 25 | +4 | The Wackness | $145,000 | $138,401 | -$6,599 | -4.6% | 6 | $179,000 | $172,179 | 1 | Sony Pictures Classics | - |
| 22 | 29 | +7 | When Did You Last See Your Father? | $115,000 | $100,278 | -$14,722 | -12.8% | 57 | $543,000 | $525,965 | 5 | Sony Pictures Classics | - |
| 23 | 30 | +7 | Brick Lane | $107,000 | $92,939 | -$14,061 | -13.1% | 33 | $279,000 | $256,692 | 3 | Sony Pictures Classics | - |
| 24 | 33 | +9 | The Fall | $93,500 | $81,288 | -$12,212 | -13.1% | 56 | $1,918,000 | $1,902,394 | 9 | Roadside Attractions | - |
| 25 | 32 | +7 | Forgetting Sarah Marshall | $90,000 | $81,795 | -$8,205 | -9.1% | 133 | $62,885,000 | $62,877,175 | 12 | Universal Pictures | - |
| 26 | 31 | +5 | Roman de gare | $88,800 | $85,266 | -$3,534 | -4% | 37 | $1,484,000 | $1,480,472 | 11 | The Samuel Goldwyn Company | - |
| 27 | 39 | +12 | The Children of Huang Shi | $61,400 | $51,451 | -$9,949 | -16.2% | 36 | $604,000 | $589,126 | 7 | Sony Pictures Classics | - |
| 28 | 42 | +14 | Priceless | $50,400 | $47,868 | -$2,532 | -5% | 33 | $1,974,000 | $1,971,305 | 15 | The Samuel Goldwyn Company | - |
| 29 | 49 | +20 | War, Inc. | $42,100 | $38,249 | -$3,851 | -9.1% | 24 | $472,000 | $467,917 | 7 | First Look International | - |
| 30 | 52 | +22 | Reprise | $28,600 | $25,862 | -$2,738 | -9.6% | 15 | $509,000 | $506,537 | 8 | Miramax | - |
| 31 | 51 | +20 | Before the Rains | $27,000 | $25,888 | -$1,112 | -4.1% | 17 | $738,000 | $737,006 | 9 | Roadside Attractions | - |
| 32 | 54 | +22 | Trumbo | $25,400 | $25,396 | -$4 | <0.1% | 6 | $69,000 | $68,944 | 2 | The Samuel Goldwyn Company | - |
| 33 | 60 | +27 | Fugitive Pieces | $15,300 | $15,449 | +$149 | +1% | 14 | $577,000 | $577,036 | 10 | The Samuel Goldwyn Company | - |
| 34 | 68 | +34 | Superhero Movie | $10,000 | $8,676 | -$1,324 | -13.2% | 18 | $25,854,000 | $25,852,624 | 15 | - | - |
| 35 | 75 | +40 | The Year My Parents Went on Vacation | $6,800 | $7,280 | +$480 | +7.1% | 4 | $797,000 | $797,598 | 21 | City Lights Pictures | - |
| 36 | 87 | +51 | Baghead | $4,500 | $3,414 | -$1,086 | -24.1% | 2 | $26,600 | $25,571 | 4 | Sony Pictures Classics | - |
| 37 | 102 | +65 | My Blueberry Nights | $1,800 | $1,605 | -$195 | -10.8% | 7 | $865,000 | $863,802 | 14 | The Weinstein Company | - |
