| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Incredible Hulk | $330,569 | -61% | 24 | -10 | $13,773 | $1,415,150 | 2 | N/A | false | false |
| 2 | 2 | Kung Fu Panda | $176,753 | -42.1% | 18 | -1 | $9,819 | $1,357,024 | 3 | N/A | false | false |
| 3 | - | The Strangers | $155,854 | - | 19 | - | $8,202 | $155,854 | 1 | N/A | true | false |
| 4 | - | The Killing Gene | $86,375 | - | 14 | - | $6,169 | $86,375 | 1 | N/A | true | false |
| 5 | - | Semi-Pro | $68,634 | - | 19 | - | $3,612 | $68,634 | 1 | N/A | true | false |
| 6 | - | Wolfhound | $68,352 | - | 18 | - | $3,797 | $95,313 | 1 | N/A | true | false |
| 7 | 3 | Chief Omar Harb | $55,020 | -55.9% | 8 | -4 | $6,877 | $239,988 | 2 | N/A | false | false |
| 8 | 4 | Can't Complain | $37,030 | -48.8% | 9 | -7 | $4,114 | $871,321 | 4 | N/A | false | false |
| 9 | - | Son of Rambow | $35,696 | - | 14 | - | $2,549 | $35,696 | 1 | N/A | true | false |
| 10 | 7 | The Chronicles of Narnia: Prince Caspian | $21,136 | -58.5% | 3 | -8 | $7,045 | $805,261 | 4 | N/A | false | false |
| 11 | 5 | The Happening | $10,377 | -81.7% | 3 | -13 | $3,459 | $405,609 | 3 | N/A | false | false |
| 12 | 9 | The Forbidden Kingdom | $8,489 | -66.4% | 3 | -10 | $2,829 | $1,242,595 | 5 | N/A | false | false |
| 13 | 10 | Indiana Jones and the Kingdom of the Crystal Skull | $8,218 | -54% | 2 | -1 | $4,109 | $1,470,492 | 6 | N/A | false | false |
| 14 | 6 | I Could Never Be Your Woman | $6,473 | -88.1% | 2 | -13 | $3,236 | $87,545 | 2 | N/A | false | false |
| 15 | 13 | Iron Man | $6,075 | +39.2% | 1 | - | $6,075 | $1,814,143 | 9 | N/A | false | false |
| 16 | 11 | The Bank Job | $4,029 | -76.7% | 1 | -7 | $4,029 | $348,517 | 4 | N/A | false | false |
| 17 | - | Al Turbini | $4,020 | - | 4 | - | $1,005 | $4,020 | 1 | N/A | true | false |
| 18 | 12 | What Happens in Vegas | $3,907 | -60.2% | 1 | -1 | $3,907 | $698,672 | 7 | N/A | false | false |
| 19 | 8 | Never Back Down | $2,348 | -92% | 1 | -17 | $2,348 | $271,048 | 3 | N/A | false | false |
