| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Incredible Hulk | $331,447 | - | 36 | - | $9,206 | $340,522 | 1 | N/A | true | false |
| 2 | - | The Happening | $186,662 | - | 35 | - | $5,333 | $186,662 | 1 | N/A | true | false |
| 3 | 1 | What Happens in Vegas | $72,853 | -60% | 27 | - | $2,698 | $363,709 | 2 | N/A | false | false |
| 4 | 3 | The Chronicles of Narnia: Prince Caspian | $47,147 | -52.1% | 60 | - | $785 | $1,359,867 | 5 | N/A | false | false |
| 5 | 2 | Indiana Jones and the Kingdom of the Crystal Skull | $33,428 | -69.5% | 59 | - | $566 | $1,131,507 | 4 | N/A | false | false |
| 6 | - | Mr. Woodcock | $23,628 | - | 14 | - | $1,687 | $23,628 | 1 | N/A | true | false |
| 7 | 7 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $21,009 | -27.4% | 1 | - | $21,009 | $63,188 | 2 | N/A | false | false |
| 8 | 5 | 21 | $16,289 | -63.1% | 12 | -8 | $1,357 | $184,299 | 3 | N/A | false | false |
| 9 | 4 | P2 | $10,165 | -79.5% | 23 | - | $441 | $82,743 | 2 | N/A | false | false |
| 10 | 6 | Diary of the Dead | $6,406 | -80.8% | 14 | - | $457 | $145,115 | 3 | N/A | false | false |
| 11 | 8 | Speed Racer | $4,222 | -83.8% | 64 | - | $65 | $1,025,893 | 6 | N/A | false | false |
| 12 | 9 | Street Kings | $2,888 | -83.9% | 17 | - | $169 | $92,885 | 3 | N/A | false | false |
| 13 | 13 | P.S. I Love You | $2,220 | -7% | 23 | - | $96 | $455,809 | 9 | N/A | false | false |
| 14 | 11 | Fragile | $1,498 | -78.6% | 14 | - | $107 | $114,279 | 13 | N/A | false | false |
| 15 | - | Horton Hears a Who! | $1,380 | - | 48 | - | $28 | $607,222 | 14 | N/A | false | false |
| 16 | 10 | Shattered | $1,075 | -84.9% | 13 | - | $82 | $120,279 | 8 | N/A | false | false |
| 17 | 12 | Iron Man | $822 | -88% | 46 | - | $17 | $1,331,617 | 7 | N/A | false | false |
| 18 | 17 | Dead Silence | $484 | -63.5% | 20 | - | $24 | $131,636 | 12 | N/A | false | false |
| 19 | 19 | Fool's Gold | $164 | -83.6% | 18 | - | $9 | $171,538 | 10 | N/A | false | false |
| 20 | - | Noah's Ark | $49 | - | 23 | - | $2 | $225,839 | 19 | N/A | false | false |
