| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Indiana Jones and the Kingdom of the Crystal Skull | $2,896,117 | -53.9% | 720 | -8 | $4,022 | $24,464,313 | 3 | Universal Pictures International (UPI) | false | false |
| 2 | 2 | Made of Honor | $1,143,168 | -46.4% | 330 | +1 | $3,464 | $3,698,251 | 2 | Sony Pictures Releasing | false | false |
| 3 | 3 | The Mist | $718,510 | -34.8% | 272 | - | $2,641 | $2,064,434 | 2 | Notro Films | false | false |
| 4 | 4 | What Happens in Vegas | $554,700 | -38.2% | 341 | -24 | $1,626 | $10,567,123 | 5 | 20th Century Fox International | false | false |
| 5 | 5 | Before the Devil Knows You're Dead | $394,588 | -27% | 106 | - | $3,722 | $1,833,114 | 3 | Baditri | false | false |
| 6 | - | Leatherheads | $383,974 | - | 127 | - | $3,023 | $383,974 | 1 | Universal Pictures International (UPI) | true | false |
| 7 | - | Emotional Arithmetic | $204,558 | - | 43 | - | $4,757 | $204,558 | 1 | Golem Distribución | true | false |
| 8 | 9 | 88 Minutes | $180,424 | -12.7% | 165 | +5 | $1,093 | $3,492,152 | 6 | Filmax | false | false |
| 9 | 6 | Iron Man | $175,620 | -38% | 265 | -35 | $662 | $11,341,429 | 6 | Sony Pictures Releasing | false | false |
| 10 | 7 | Chef's Special | $172,820 | -31.4% | 159 | -20 | $1,086 | $7,364,643 | 9 | Warner Bros. | false | false |
| 11 | 8 | Prom Night | $155,761 | -30.7% | 184 | -25 | $846 | $1,630,283 | 4 | Sony Pictures Releasing | false | false |
| 12 | 10 | Death Sentence | $108,302 | -18.1% | 125 | -9 | $866 | $1,116,380 | 4 | TriPictures | false | false |
| 13 | 12 | Elegy | $74,557 | -25.1% | 94 | -1 | $793 | $3,630,041 | 8 | On Pictures | false | false |
| 14 | 13 | Street Kings | $69,987 | -25.9% | 94 | -24 | $744 | $4,020,481 | 7 | 20th Century Fox International | false | false |
| 15 | 15 | 21 | $67,689 | -23.4% | 92 | -15 | $735 | $6,642,001 | 9 | Sony Pictures Releasing | false | false |
| 16 | 11 | Speed Racer | $65,879 | -38.8% | 159 | -44 | $414 | $1,901,528 | 5 | Warner Bros. | false | false |
| 17 | 14 | Casual Day | $61,416 | -33.3% | 97 | +2 | $633 | $1,277,559 | 5 | Walt Disney Pictures | false | false |
| 18 | - | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $60,760 | - | 13 | - | $4,673 | $60,760 | 1 | Walt Disney Pictures | true | false |
| 19 | 20 | Island of Lost Souls | $43,476 | -12.5% | 57 | +7 | $762 | $344,259 | 4 | - | false | false |
| 20 | 17 | Courthouse on Horseback | $36,871 | -37.6% | 17 | +1 | $2,168 | $206,051 | 3 | Karma Films | false | false |
| 21 | 22 | The Game Plan | $36,551 | -24.7% | 84 | -9 | $435 | $5,828,131 | 11 | Walt Disney Pictures | false | false |
| 22 | 19 | Horton Hears a Who! | $35,259 | -37.1% | 99 | -5 | $356 | $10,994,317 | 13 | 20th Century Fox International | false | false |
| 23 | 16 | A Girl Cut in Two | $32,342 | -46.7% | 36 | -3 | $898 | $443,808 | 4 | Wanda Visión S.A. | false | false |
| 24 | 18 | The Dead Girl | $32,025 | -43.5% | 32 | - | $1,000 | $109,293 | 2 | Filmax | false | false |
| 25 | 24 | Drillbit Taylor | $31,747 | +7.6% | 62 | +4 | $512 | $371,756 | 4 | Universal Pictures International (UPI) | false | false |
| 26 | 21 | A Thousand Years of Good Prayers | $27,890 | -42.6% | 33 | -2 | $845 | $1,068,187 | 8 | Karma Films | false | false |
| 27 | 25 | Rudy: The Return of the Racing Pig | $23,819 | -16.4% | 50 | +8 | $476 | $352,997 | 7 | - | false | false |
| 28 | 23 | Late Bloomers | $22,548 | -38.1% | 18 | +2 | $1,252 | $328,164 | 5 | - | false | false |
| 29 | 28 | The Edge of Heaven | $18,162 | -19.8% | 15 | -1 | $1,210 | $1,243,970 | 13 | Golem Distribución | false | false |
| 30 | 26 | The Counterfeiters | $16,225 | -36.1% | 22 | -3 | $737 | $3,784,061 | 13 | Wanda Visión S.A. | false | false |
| 31 | 29 | Alexandra | $14,278 | -34% | 8 | +1 | $1,784 | $45,362 | 2 | Sagrera TV | false | false |
| 32 | 37 | Lars and the Real Girl | $13,164 | -4.2% | 13 | +3 | $1,012 | $237,660 | 7 | Versus Entertainment | false | false |
| 33 | 27 | Fool's Gold | $12,143 | -47.7% | 35 | -27 | $346 | $2,892,362 | 7 | Warner Bros. | false | false |
| 34 | 32 | 8 Dates | $11,980 | -30% | 19 | -2 | $630 | $1,304,211 | 8 | Alta Films | false | false |
| 35 | 47 | Enloquecidas | $11,772 | +39.2% | 2 | -2 | $5,886 | $194,767 | 9 | Premium Film | false | false |
| 36 | 30 | Cowards | $11,469 | -44.3% | 34 | -7 | $337 | $1,455,862 | 7 | Filmax | false | false |
| 37 | 46 | My Mom's New Boyfriend | $11,436 | +32.6% | 25 | -3 | $457 | $1,335,059 | 6 | DeAPlaneta | false | false |
| 38 | 34 | The Savages | $11,377 | -26.1% | 21 | -1 | $541 | $921,218 | 10 | 20th Century Fox International | false | false |
| 39 | - | Encarnacion | $11,009 | - | 5 | - | $2,201 | $11,009 | 1 | Wanda Visión S.A. | true | false |
| 40 | - | Night Watch | $10,620 | - | 5 | - | $2,124 | $32,118 | 67 | Sagrera TV | false | false |
| 41 | 40 | Be Kind Rewind | $10,479 | -5.8% | 1 | -8 | $10,479 | $491,617 | 9 | Universal Pictures International (UPI) | false | false |
| 42 | 36 | Nightwatching | $10,464 | -28.6% | 5 | - | $2,092 | $31,645 | 2 | Manga Entertainment | false | false |
| 43 | 31 | Shutter | $10,156 | -48.8% | 30 | -10 | $338 | $3,727,885 | 9 | 20th Century Fox International | false | false |
| 44 | 41 | The Contract | $9,782 | -8.2% | 20 | +1 | $489 | $1,370,148 | 10 | Filmax | false | false |
| 45 | 35 | The Band's Visit | $9,609 | -36.9% | 11 | -4 | $873 | $436,447 | 9 | Manga Entertainment | false | false |
| 46 | 57 | Shattered | $8,057 | +85.3% | 13 | +2 | $619 | $456,543 | 6 | Manga Entertainment | false | false |
| 47 | 43 | The Water Horse | $6,963 | -31.4% | 20 | -5 | $348 | $3,417,015 | 14 | Sony Pictures Releasing | false | false |
| 48 | 38 | Sultanes del Sur | $5,961 | -53.6% | 10 | -2 | $596 | $151,001 | 4 | Filmax | false | false |
| 49 | 48 | Todos estamos invitados | $5,776 | -30.3% | 14 | -3 | $412 | $1,245,250 | 9 | Alta Films | false | false |
| 50 | 42 | Days of Darkness | $5,334 | -48.1% | 10 | -1 | $533 | $352,696 | 9 | Golem Distribución | false | false |
| 51 | 55 | Bab'Aziz: The Prince That Contemplated His Soul | $5,128 | -0.5% | 5 | - | $1,025 | $226,161 | 14 | Karma Films | false | false |
| 52 | 49 | Franklin and the Turtle Lake Treasure | $4,958 | -34.1% | 15 | +1 | $330 | $753,126 | 16 | Wanda Visión S.A. | false | false |
| 53 | 51 | The Yacoubian Building | $4,936 | -24.3% | 2 | - | $2,468 | $14,482 | 2 | Barton Films | false | false |
| 54 | 65 | La crisis carnívora | $4,797 | +87.7% | 18 | +1 | $266 | $94,858 | 4 | - | false | false |
| 55 | 45 | A Tram in SP | $4,457 | -48.6% | 17 | -6 | $262 | $271,475 | 6 | - | false | false |
| 56 | 39 | Honeydripper | $4,125 | -63.4% | 7 | +2 | $589 | $69,517 | 4 | Golem Distribución | false | false |
| 57 | 61 | Cashback | $3,965 | +2.7% | 6 | -1 | $660 | $192,626 | 9 | - | false | false |
| 58 | 68 | Rendition | $3,948 | +104.6% | 11 | +4 | $358 | $1,322,220 | 8 | TriPictures | false | false |
| 59 | 59 | The Pope's Toilet | $2,898 | -31.5% | 6 | -3 | $483 | $95,030 | 7 | Golem Distribución | false | false |
| 60 | 66 | Death Defying Acts | $2,575 | +13.2% | 7 | +1 | $367 | $2,912,334 | 10 | DeAPlaneta | false | false |
| 61 | 53 | The Duchess of Langeais | $2,444 | -56.2% | 4 | -3 | $611 | $169,998 | 6 | Baditri | false | false |
| 62 | 64 | Caramel | $2,376 | -11.1% | 4 | - | $594 | $1,871,134 | 21 | Alta Films | false | false |
| 63 | 77 | Closing the Ring | $2,110 | +267.6% | 4 | +3 | $527 | $274,877 | 13 | Manga Entertainment | false | false |
| 64 | 54 | Fay Grim | $1,992 | -61.9% | 3 | - | $664 | $9,429 | 2 | Avalon | false | false |
| 65 | 62 | The Aerial | $1,151 | -63.2% | 1 | -2 | $1,151 | $41,919 | 5 | Sherlock Films | false | false |
| 66 | 75 | Buddha Collapsed Out of Shame | $1,110 | +75.4% | 4 | +1 | $277 | $479,086 | 15 | Wanda Visión S.A. | false | false |
| 67 | 73 | The Silence Before Bach | $883 | +27.6% | 2 | +1 | $441 | $329,541 | 25 | Sherlock Films | false | false |
| 68 | 72 | 4 Months, 3 Weeks and 2 Days | $710 | -32.1% | 2 | - | $355 | $1,089,971 | 20 | Golem Distribución | false | false |
| 69 | 70 | One Missed Call | $631 | -58.3% | 2 | -1 | $315 | $2,159,301 | 12 | Warner Bros. | false | false |
| 70 | 69 | Broken Sky | $578 | -66.5% | 2 | - | $289 | $25,225 | 4 | Karma Films | false | false |
| 71 | 82 | Before the Fall | $567 | +196.9% | 1 | - | $567 | $314,810 | 7 | Universal Pictures International (UPI) | false | false |
| 72 | - | Ellos robaron la picha de Hitler | $549 | - | 2 | - | $274 | $549 | 1 | Manga Entertainment | true | false |
| 73 | 79 | Into the Wild | $492 | +18% | 1 | -1 | $492 | $771,205 | 20 | Universal Pictures International (UPI) | false | false |
| 74 | 63 | Dan in Real Life | $315 | -88.8% | 1 | -2 | $315 | $2,706,563 | 12 | Universal Pictures International (UPI) | false | false |
| 75 | 81 | 10,000 BC | $229 | +11.2% | 2 | -1 | $114 | $13,119,769 | 14 | Warner Bros. | false | false |
| 76 | 80 | Asterix at the Olympic Games | $170 | -50.6% | 2 | -1 | $85 | $9,180,236 | 18 | TriPictures | false | false |
