| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Indiana Jones and the Kingdom of the Crystal Skull | $129,153 | -34.5% | 19 | -2 | $6,797 | $393,250 | 2 | Prooptiki | false | false |
| 2 | - | 88 Minutes | $30,996 | - | 5 | - | $6,199 | $30,996 | 1 | Alexandra Films | true | false |
| 3 | 2 | What Happens in Vegas | $21,044 | -6.7% | 7 | - | $3,006 | $123,832 | 3 | Alexandra Films | false | false |
| 4 | 3 | Horton Hears a Who! | $10,877 | +88.2% | 9 | - | $1,208 | $154,929 | 6 | Alexandra Films | false | false |
| 5 | - | Love in the Time of Cholera | $9,532 | - | 4 | - | $2,383 | $9,532 | 1 | Prooptiki | true | false |
| 6 | 4 | 21 | $4,340 | -23.9% | 9 | - | $482 | $117,083 | 4 | Alexandra Films | false | false |
| 7 | 5 | Iron Man | $3,928 | -25.1% | 9 | - | $436 | $145,463 | 5 | Prooptiki | false | false |
| 8 | 6 | Fool's Gold | $2,731 | -30.9% | 8 | - | $341 | $131,704 | 5 | Alexandra Films | false | false |
| 9 | - | Surviving with Wolves | $2,529 | - | 4 | - | $632 | $2,529 | 1 | Sunny Films | true | false |
| 10 | 7 | Speed Racer | $2,327 | -15.4% | 6 | +2 | $387 | $12,722 | 3 | Alexandra Films | false | false |
| 11 | 8 | 99 Francs | $1,107 | -11.2% | 3 | - | $369 | $10,444 | 4 | Big Bang Media | false | false |
| 12 | 11 | The Spiderwick Chronicles | $513 | +0.6% | 3 | - | $171 | $72,297 | 9 | Prooptiki | false | false |
| 13 | 9 | Street Kings | $448 | -61.4% | 3 | -2 | $149 | $126,151 | 7 | Alexandra Films | false | false |
| 14 | 16 | The Bucket List | $364 | +158.2% | 3 | -1 | $121 | $101,635 | 8 | Alexandra Films | false | false |
| 15 | 21 | Definitely, Maybe | $238 | +934.8% | 2 | +1 | $119 | $18,680 | 8 | Prooptiki | false | false |
| 16 | 19 | The Game Plan | $187 | +142.9% | 3 | -1 | $62 | $82,672 | 11 | Sunny Films | false | false |
| 17 | 10 | Forgetting Sarah Marshall | $178 | -70.1% | 2 | - | $89 | $41,458 | 6 | Prooptiki | false | false |
| 18 | 13 | Mad Money | $158 | -28.2% | 5 | - | $31 | $34,884 | 7 | Sunny Films | false | false |
| 19 | 12 | The Eye | $158 | -42.3% | 3 | -2 | $52 | $38,685 | 6 | Alexandra Films | false | false |
| 20 | 24 | No Country for Old Men | $76 | +660% | 1 | - | $76 | $79,587 | 15 | Prooptiki | false | false |
| 21 | 14 | There Will Be Blood | $67 | -62.4% | 1 | -3 | $67 | $24,133 | 10 | Sunny Films | false | false |
| 22 | 15 | The Mist | $53 | -69.5% | 1 | -2 | $53 | $25,797 | 9 | Sunny Films | false | false |
| 23 | - | La Vie En Rose | $48 | - | 3 | - | $16 | $32,636 | 53 | Alexandra Films | false | false |
| 24 | - | Ratatouille | $40 | - | 2 | - | $20 | $257,013 | 38 | Sunny Films | false | false |
| 25 | - | The Chronicles of Narnia: The Lion, the Witch and the Wardrobe | $40 | - | 1 | - | $40 | $259,250 | 128 | Sunny Films | false | false |
| 26 | - | Georgi and the Butterflies | $14 | - | 1 | - | $14 | $7,628 | 164 | Sunny Films | false | false |
| 27 | 18 | The Mosquito Problem and Other Stories | $11 | -85.9% | 2 | - | $5 | $2,755 | 12 | Sunny Films | false | false |
| 28 | - | All the Invisible Children | $4 | - | 1 | - | $4 | $2,862 | 78 | Big Bang Media | false | false |
