| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Iron Man | $565,379 | - | 46 | - | $12,290 | $642,317 | 1 | N/A | true | false |
| 2 | 1 | P.S. I Love You | $73,787 | -17.4% | 23 | - | $3,208 | $354,443 | 3 | N/A | false | false |
| 3 | - | Eastern Promises | $58,339 | - | 20 | - | $2,916 | $63,076 | 1 | N/A | true | false |
| 4 | - | Black Christmas | $54,471 | - | 16 | - | $3,404 | $54,471 | 1 | N/A | true | false |
| 5 | 2 | The Marsh | $52,902 | -5.1% | 21 | - | $2,519 | $131,210 | 2 | N/A | false | false |
| 6 | 4 | Shattered | $29,733 | -27.9% | 13 | - | $2,287 | $85,310 | 2 | N/A | false | false |
| 7 | 6 | Drillbit Taylor | $27,201 | -33.6% | 14 | - | $1,942 | $137,526 | 3 | N/A | false | false |
| 8 | 3 | The Orphanage | $27,160 | -40.8% | 28 | - | $970 | $483,238 | 5 | N/A | false | false |
| 9 | 5 | Shutter | $18,723 | -54.5% | 18 | - | $1,040 | $158,405 | 3 | N/A | false | false |
| 10 | 7 | Meet the Spartans | $17,170 | -26.5% | 20 | - | $858 | $263,557 | 5 | N/A | false | false |
| 11 | 8 | The Spiderwick Chronicles | $14,664 | -29.7% | 38 | - | $385 | $385,742 | 7 | N/A | false | false |
| 12 | 14 | Untraceable | $7,795 | -14.3% | 5 | - | $1,559 | $159,036 | 8 | N/A | false | false |
| 13 | 9 | Fool's Gold | $7,788 | -60.4% | 18 | - | $432 | $169,164 | 4 | N/A | false | false |
| 14 | 16 | One Missed Call | $7,443 | +2.4% | 18 | - | $413 | $206,247 | 8 | N/A | false | false |
| 15 | 10 | Vantage Point | $7,408 | -62.1% | 6 | -5 | $1,234 | $230,115 | 5 | N/A | false | false |
| 16 | 13 | Horton Hears a Who! | $7,120 | -43.5% | 48 | - | $148 | $609,620 | 8 | N/A | false | false |
| 17 | 15 | Noah's Ark | $5,642 | -29.4% | 23 | - | $245 | $225,977 | 13 | N/A | false | false |
| 18 | 11 | Minotaur | $4,429 | -75.3% | 29 | - | $152 | $28,774 | 2 | N/A | false | false |
| 19 | 19 | Charlie Wilson's War | $2,544 | -40.3% | 12 | - | $212 | $117,491 | 10 | N/A | false | false |
| 20 | 20 | School for Scoundrels | $1,772 | -55% | 13 | - | $136 | $77,187 | 15 | N/A | false | false |
| 21 | 24 | La Vie En Rose | $1,495 | -51.2% | 5 | - | $299 | $106,998 | 7 | N/A | false | false |
| 22 | 33 | There Will Be Blood | $1,238 | +187.9% | 8 | - | $154 | $106,472 | 11 | N/A | false | false |
| 23 | - | 30 Days of Night | $1,196 | - | 2 | - | $598 | $134,083 | 10 | N/A | false | false |
| 24 | 21 | Material Girls | $1,076 | -70.4% | 9 | - | $119 | $53,566 | 14 | N/A | false | false |
| 25 | 23 | Valentino y el clan del can | $894 | -74.7% | 30 | - | $29 | $315,451 | 10 | N/A | false | false |
| 26 | - | Silent Light | $846 | - | 2 | - | $423 | $12,642 | 6 | N/A | false | false |
| 27 | - | Gone Baby Gone | $431 | - | 10 | - | $43 | $43,535 | 12 | N/A | false | false |
| 28 | 31 | The Bucket List | $426 | -52% | 14 | - | $30 | $401,915 | 13 | N/A | false | false |
| 29 | 17 | The Eye | $289 | -94.2% | 20 | - | $14 | $105,301 | 4 | N/A | false | false |
| 30 | 12 | The Hitcher | $88 | -99.4% | 14 | - | $6 | $66,001 | 3 | N/A | false | false |
| 31 | 25 | 27 Dresses | $67 | -97.7% | 17 | - | $3 | $286,072 | 12 | N/A | false | false |
