| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | 21 | $1,413,325 | -25.7% | 255 | +4 | $5,542 | $3,703,073 | 2 | Sony Pictures Releasing | false | false |
| 2 | 2 | Chef's Special | $1,307,098 | -12.7% | 232 | +1 | $5,634 | $3,166,449 | 2 | Warner Bros. | false | false |
| 3 | - | Elegy | $967,742 | - | 127 | - | $7,620 | $968,123 | 1 | On Pictures | true | false |
| 4 | 3 | Shutter | $966,204 | -30.1% | 299 | -1 | $3,231 | $2,557,288 | 2 | 20th Century Fox International | false | false |
| 5 | - | Never Back Down | $834,660 | - | 202 | - | $4,131 | $834,660 | 1 | - | true | false |
| 6 | 4 | The Game Plan | $693,855 | -15.8% | 250 | - | $2,775 | $4,491,022 | 4 | Walt Disney Pictures | false | false |
| 7 | - | Rendition | $639,326 | - | 222 | - | $2,879 | $640,544 | 1 | TriPictures | true | false |
| 8 | - | 8 Dates | $488,357 | - | 171 | - | $2,855 | $488,357 | 1 | Alta Films | true | false |
| 9 | - | The Ruins | $452,514 | - | 200 | - | $2,262 | $452,514 | 1 | Universal Pictures International (UPI) | true | false |
| 10 | 6 | Death Defying Acts | $413,152 | -37.5% | 248 | -2 | $1,665 | $2,573,575 | 3 | DeAPlaneta | false | false |
| 11 | 7 | Horton Hears a Who! | $407,921 | -8.9% | 272 | -46 | $1,499 | $10,303,675 | 6 | 20th Century Fox International | false | false |
| 12 | 5 | Meet the Spartans | $359,356 | -51.7% | 303 | -12 | $1,185 | $6,394,598 | 4 | 20th Century Fox International | false | false |
| 13 | 8 | Todos estamos invitados | $274,217 | -38.2% | 111 | - | $2,470 | $842,440 | 2 | Alta Films | false | false |
| 14 | 10 | We Own the Night | $243,280 | -42.2% | 180 | -43 | $1,351 | $3,464,728 | 4 | Universal Pictures International (UPI) | false | false |
| 15 | 9 | Untraceable | $224,143 | -48.2% | 178 | -23 | $1,259 | $1,698,661 | 3 | Universal Pictures International (UPI) | false | false |
| 16 | 13 | The Spiderwick Chronicles | $212,860 | -8.8% | 160 | -43 | $1,330 | $5,335,475 | 6 | Universal Pictures International (UPI) | false | false |
| 17 | - | A Thousand Years of Good Prayers | $194,625 | - | 36 | - | $5,406 | $194,625 | 1 | Karma Films | true | false |
| 18 | 11 | The Contract | $193,848 | -34.2% | 110 | -11 | $1,762 | $1,154,172 | 3 | Filmax | false | false |
| 19 | 12 | The Counterfeiters | $168,520 | -28.9% | 105 | -10 | $1,604 | $3,337,468 | 6 | Wanda Visión S.A. | false | false |
| 20 | 21 | The Water Horse | $102,361 | +4.8% | 122 | -16 | $839 | $3,224,938 | 7 | Sony Pictures Releasing | false | false |
| 21 | 14 | The Savages | $100,748 | -40.7% | 47 | -1 | $2,143 | $601,815 | 3 | 20th Century Fox International | false | false |
| 22 | 19 | Be Kind Rewind | $81,229 | -21.7% | 32 | +1 | $2,538 | $221,640 | 2 | Universal Pictures International (UPI) | false | false |
| 23 | 16 | 10,000 BC | $78,520 | -49.5% | 97 | -61 | $809 | $12,952,713 | 7 | Warner Bros. | false | false |
| 24 | 20 | The Band's Visit | $69,831 | -30.6% | 27 | - | $2,586 | $205,021 | 2 | Manga Entertainment | false | false |
| 25 | 15 | Awake | $62,463 | -62.1% | 88 | -92 | $709 | $1,472,762 | 4 | - | false | false |
| 26 | 22 | The Edge of Heaven | $57,530 | -32.2% | 29 | -4 | $1,983 | $982,771 | 6 | Golem Distribución | false | false |
| 27 | 17 | The Other Boleyn Girl | $55,776 | -50.7% | 62 | -47 | $899 | $5,871,305 | 8 | Universal Pictures International (UPI) | false | false |
| 28 | 23 | Days of Darkness | $53,796 | -35% | 26 | - | $2,069 | $165,703 | 2 | Golem Distribución | false | false |
| 29 | 26 | The Kite Runner | $52,820 | -19.1% | 42 | -13 | $1,257 | $1,669,138 | 7 | Universal Pictures International (UPI) | false | false |
| 30 | 18 | Dan in Real Life | $41,093 | -60.9% | 51 | -59 | $805 | $2,652,710 | 5 | Universal Pictures International (UPI) | false | false |
| 31 | 25 | Silk | $37,696 | -48.1% | 54 | -47 | $698 | $2,022,780 | 5 | TriPictures | false | false |
| 32 | 27 | Juno | $35,675 | -40% | 38 | -21 | $938 | $8,261,145 | 12 | 20th Century Fox International | false | false |
| 33 | 29 | Cashback | $30,559 | -39.3% | 26 | - | $1,175 | $98,905 | 2 | - | false | false |
| 34 | 24 | One Missed Call | $27,185 | -66.3% | 63 | -57 | $431 | $2,119,217 | 5 | Warner Bros. | false | false |
| 35 | 34 | Enloquecidas | $25,402 | -6.1% | 8 | -2 | $3,175 | $68,959 | 2 | Premium Film | false | false |
| 36 | 30 | Shine a Light | $23,712 | -49.5% | 32 | -25 | $741 | $244,220 | 3 | Vértigo Films | false | false |
| 37 | 41 | Asterix at the Olympic Games | $15,389 | +5.7% | 30 | -13 | $512 | $9,072,048 | 11 | TriPictures | false | false |
| 38 | 45 | Franklin and the Turtle Lake Treasure | $14,308 | +56% | 25 | +2 | $572 | $693,951 | 9 | Wanda Visión S.A. | false | false |
| 39 | 35 | Charlie Wilson's War | $12,887 | -48.9% | 15 | -10 | $859 | $4,426,996 | 9 | Universal Pictures International (UPI) | false | false |
| 40 | 31 | The Eye | $11,315 | -71.7% | 32 | -51 | $353 | $2,861,691 | 6 | DeAPlaneta | false | false |
| 41 | 36 | No Country for Old Men | $10,405 | -47.7% | 16 | -17 | $650 | $11,284,429 | 11 | Universal Pictures International (UPI) | false | false |
| 42 | 33 | Vantage Point | $9,926 | -68.7% | 26 | -35 | $381 | $6,718,470 | 8 | Sony Pictures Releasing | false | false |
| 43 | 32 | 27 Dresses | $9,668 | -73.9% | 24 | -42 | $402 | $6,515,837 | 8 | 20th Century Fox International | false | false |
| 44 | 43 | Bab'Aziz: The Prince That Contemplated His Soul | $9,393 | -18.1% | 4 | - | $2,348 | $159,429 | 7 | Karma Films | false | false |
| 45 | 28 | Rogue | $8,917 | -82.8% | 33 | -77 | $270 | $287,402 | 3 | Notro Films | false | false |
| 46 | 37 | 4 Months, 3 Weeks and 2 Days | $8,155 | -53.6% | 12 | - | $679 | $1,053,443 | 13 | Golem Distribución | false | false |
| 47 | 44 | Joe Strummer: The Future Is Unwritten | $6,495 | -35.4% | 4 | - | $1,623 | $42,028 | 3 | Avalon | false | false |
| 48 | 38 | There Will Be Blood | $6,342 | -63% | 11 | -15 | $576 | $2,420,408 | 10 | Walt Disney Pictures | false | false |
| 49 | 47 | Caramel | $6,125 | -27.8% | 8 | +2 | $765 | $1,789,583 | 14 | Alta Films | false | false |
| 50 | 42 | Sleeping Dogs Lie | $5,722 | -57.2% | 13 | -5 | $440 | $338,254 | 7 | - | false | false |
| 51 | 46 | The Bucket List | $5,686 | -37% | 5 | -1 | $1,137 | $5,682,938 | 12 | Warner Bros. | false | false |
| 52 | 39 | Lo mejor de mí | $5,263 | -68.4% | 8 | -8 | $657 | $398,989 | 7 | Alta Films | false | false |
| 53 | 52 | Irina Palm | $5,082 | +11.7% | 18 | +15 | $282 | $807,803 | 19 | Golem Distribución | false | false |
| 54 | 40 | Buddha Collapsed Out of Shame | $4,617 | -69.7% | 11 | -5 | $419 | $449,471 | 8 | Wanda Visión S.A. | false | false |
| 55 | 48 | Sweeney Todd: The Demon Barber of Fleet Street | $3,641 | -53.2% | 10 | -5 | $364 | $5,141,494 | 10 | Warner Bros. | false | false |
| 56 | 51 | It's a Free World... | $2,514 | -49.6% | 3 | -1 | $838 | $562,572 | 9 | Alta Films | false | false |
| 57 | 57 | Love and Honor | $2,364 | -13.6% | 3 | +1 | $788 | $33,188 | 4 | Notro Films | false | false |
| 58 | 50 | Jumper | $2,306 | -61.1% | 11 | -9 | $209 | $10,448,873 | 10 | 20th Century Fox International | false | false |
| 59 | 54 | The Oxford Murders | $2,219 | -36.9% | 7 | -3 | $317 | $12,635,860 | 14 | Warner Bros. | false | false |
| 60 | 56 | The Silence Before Bach | $2,075 | -27.7% | 2 | - | $1,037 | $312,969 | 18 | Sherlock Films | false | false |
| 61 | 58 | La soledad | $1,479 | -44.9% | 5 | -2 | $295 | $1,020,921 | 47 | Wanda Visión S.A. | false | false |
| 62 | 49 | Women on the Verge of a Nervous Breakdown 2008 Re-release | $1,393 | -77% | 5 | - | $278 | $9,965 | 2 | Warner Bros. | false | false |
| 63 | 59 | Once | $1,144 | -49% | 2 | -1 | $572 | $886,258 | 25 | Avalon | false | false |
| 64 | 65 | 30 Days of Night | $940 | -20.5% | 4 | -2 | $235 | $4,099,136 | 11 | Sony Pictures Releasing | false | false |
| 65 | 62 | LT22 Radio La Colifata | $934 | -51.9% | 1 | -2 | $934 | $8,394 | 3 | Sagrera TV | false | false |
| 66 | 64 | Into the Wild | $851 | -45.6% | 2 | -1 | $425 | $809,173 | 13 | Universal Pictures International (UPI) | false | false |
| 67 | 60 | Love Sick 2008 Re-release | $718 | -68% | 3 | -3 | $239 | $35,466 | 4 | Baditri | false | false |
| 68 | 70 | The Call of Wild | $706 | +7.1% | 3 | -2 | $235 | $96,021 | 7 | Notro Films | false | false |
| 69 | 66 | American Gangster | $551 | -47.7% | 3 | -1 | $183 | $14,658,374 | 17 | Universal Pictures International (UPI) | false | false |
| 70 | 74 | This Is England | $546 | -11.5% | 1 | -1 | $546 | $739,369 | 16 | - | false | false |
| 71 | 55 | Private Fears in Public Places | $476 | -84.2% | 2 | -4 | $238 | $288,221 | 10 | Baditri | false | false |
| 72 | 69 | Atonement | $369 | -47.8% | 1 | -2 | $369 | $6,137,012 | 15 | Universal Pictures International (UPI) | false | false |
| 73 | 77 | Lust, Caution | $304 | +60.8% | 2 | - | $152 | $2,265,677 | 19 | Universal Pictures International (UPI) | false | false |
| 74 | 79 | Across the Universe | $186 | +23.2% | 1 | -1 | $186 | $135,227 | 16 | Sony Pictures Releasing | false | false |
| 75 | 72 | KM 31: Kilometre 31 | $144 | -77.5% | 2 | -1 | $72 | $597,338 | 10 | Filmax | false | false |
