| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | 10,000 BC | $869,740 | - | 70 | - | $12,424 | $869,740 | 1 | N/A | true | false |
| 2 | - | My Big Love | $309,316 | - | 75 | - | $4,124 | $1,266,734 | 2 | N/A | false | false |
| 3 | - | Vantage Point | $67,394 | -52.2% | 35 | -12 | $1,925 | $631,902 | 3 | N/A | false | false |
| 4 | - | The Water Horse | $65,064 | -65% | 50 | - | $1,301 | $283,702 | 2 | N/A | false | false |
| 5 | - | Jumper | $56,149 | -55.7% | 37 | -21 | $1,517 | $1,532,177 | 4 | N/A | false | false |
| 6 | - | My Bestfriend's Girlfriend | $55,505 | -65.6% | 45 | -25 | $1,233 | $2,361,875 | 4 | N/A | false | false |
| 7 | - | The Spiderwick Chronicles | $38,570 | -17.2% | 30 | +6 | $1,285 | $519,131 | 4 | N/A | false | false |
| 8 | - | Sleuth | $13,645 | - | 6 | - | $2,274 | $13,645 | 1 | N/A | true | false |
| 9 | - | Across the Universe | $8,745 | - | 1 | - | $8,745 | $8,745 | 1 | N/A | true | false |
| 10 | - | The Flock | $8,347 | -83.2% | 18 | - | $463 | $72,174 | 2 | N/A | false | false |
| 11 | - | Half Blood Samurai | $8,101 | - | 15 | - | $540 | $8,101 | 1 | N/A | true | false |
| 12 | - | Untraceable | $7,046 | -59.4% | 15 | -3 | $469 | $88,302 | 3 | N/A | false | false |
| 13 | - | Dan in Real Life | $6,072 | -85.7% | 7 | -9 | $867 | $57,470 | 2 | N/A | false | false |
| 14 | - | The Kite Runner | $5,288 | -79.2% | 6 | -6 | $881 | $40,406 | 2 | N/A | false | false |
| 15 | - | 27 Dresses | $4,544 | -80.6% | 9 | -11 | $504 | $410,292 | 6 | N/A | false | false |
| 16 | - | 3:10 to Yuma | $1,301 | -95.1% | 4 | -11 | $325 | $34,111 | 2 | N/A | false | false |
| 17 | - | One Missed Call | $964 | -94.3% | 2 | -11 | $482 | $221,558 | 6 | N/A | false | false |
| 18 | - | Cloverfield | $798 | -84% | 2 | -3 | $399 | $408,579 | 6 | N/A | false | false |
| 19 | - | Alvin and the Chipmunks | $649 | -47.8% | 1 | -1 | $649 | $635,610 | 8 | N/A | false | false |
| 20 | - | Aliens vs. Predator: Requiem | $420 | -84% | 1 | -4 | $420 | $901,459 | 7 | N/A | false | false |
| 21 | - | American Gangster | $355 | -10.8% | 1 | -1 | $355 | $135,972 | 7 | N/A | false | false |
| 22 | - | Rambo | $220 | -90.9% | 1 | -4 | $220 | $707,177 | 7 | N/A | false | false |
