| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | American Gangster | $80,601 | - | 32 | - | $2,518 | $80,601 | 1 | United International Pictures | true | false |
| 2 | 1 | The Water Horse | $73,722 | +5% | 26 | - | $2,835 | $482,757 | 4 | Sony Pictures Releasing | false | false |
| 3 | 2 | The Game Plan | $66,280 | <0.1% | 21 | - | $3,156 | $863,913 | 7 | Walt Disney Pictures | false | false |
| 4 | - | One Missed Call | $65,090 | - | 20 | - | $3,254 | $65,090 | 1 | Warner Bros. | true | false |
| 5 | 8 | No Country for Old Men | $59,185 | +59.6% | 11 | - | $5,380 | $202,272 | 3 | United International Pictures | false | false |
| 6 | 3 | Sweeney Todd: The Demon Barber of Fleet Street | $42,483 | -23.5% | 18 | - | $2,360 | $400,878 | 4 | Warner Bros. | false | false |
| 7 | 7 | Juno | $39,816 | +6.4% | 15 | - | $2,654 | $107,364 | 2 | Bazuca Films | false | false |
| 8 | 10 | P.S. I Love You | $38,443 | +18.5% | 18 | - | $2,135 | $182,735 | 3 | Bazuca Films | false | false |
| 9 | 9 | The Bucket List | $36,544 | +4.8% | 14 | -3 | $2,610 | $391,611 | 5 | Warner Bros. | false | false |
| 10 | 5 | There Will Be Blood | $35,458 | -16% | 14 | - | $2,532 | $101,751 | 2 | Walt Disney Pictures | false | false |
| 11 | - | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | $29,837 | - | 1 | - | $29,837 | $29,387 | 1 | Walt Disney Pictures | true | false |
| 12 | 4 | Cloverfield | $29,348 | -32% | 28 | - | $1,048 | $365,028 | 4 | United International Pictures | false | false |
| 13 | 6 | Atonement | $29,045 | -22.7% | 10 | -4 | $2,904 | $164,742 | 3 | United International Pictures | false | false |
| 14 | - | The Hitcher | $23,556 | - | 14 | - | $1,682 | $23,556 | 1 | Bazuca Films | true | false |
| 15 | 12 | Noah's Ark | $22,383 | -19.3% | 16 | - | $1,398 | $67,411 | 2 | Walt Disney Pictures | false | false |
| 16 | 13 | 27 Dresses | $9,628 | -41.9% | 12 | -4 | $802 | $175,471 | 4 | 20th Century Fox International | false | false |
| 17 | 14 | Good Luck Chuck | $9,291 | -42.9% | 9 | -6 | $1,032 | $89,813 | 3 | Sony Pictures Releasing | false | false |
| 18 | 11 | I Am Legend | $7,049 | -76.6% | 21 | -9 | $335 | $1,236,777 | 7 | Warner Bros. | false | false |
| 19 | 18 | Enchanted | $3,625 | -40.9% | 7 | -5 | $517 | $1,377,304 | 12 | Walt Disney Pictures | false | false |
| 20 | 15 | Aliens vs. Predator: Requiem | $3,475 | -56% | 6 | -8 | $579 | $409,318 | 6 | 20th Century Fox International | false | false |
| 21 | 17 | Alvin and the Chipmunks | $3,462 | -48.1% | 11 | - | $314 | $350,954 | 11 | 20th Century Fox International | false | false |
| 22 | 16 | Love in the Time of Cholera | $3,349 | -53.4% | 5 | -2 | $669 | $350,954 | 7 | 20th Century Fox International | false | false |
| 23 | 19 | National Treasure: Book of Secrets | $2,637 | -54.4% | 3 | -3 | $879 | $996,446 | 10 | Walt Disney Pictures | false | false |
| 24 | 21 | Hannibal Rising | $1,393 | -62% | 4 | -4 | $348 | $76,879 | 5 | United International Pictures | false | false |
| 25 | 23 | Michael Clayton | $1,327 | -46.6% | 1 | -1 | $1,327 | $189,470 | 13 | Bazuca Films | false | false |
| 26 | 26 | Bridge to Terabithia | $905 | -35.8% | 3 | - | $301 | $59,313 | 9 | United International Pictures | false | false |
| 27 | 24 | Papelucho y el marciano | $565 | -73.8% | 2 | +1 | $282 | $969,819 | 42 | Bazuca Films | false | false |
| 28 | 25 | Radio Corazón | $550 | -74.4% | 1 | -1 | $550 | $1,941,625 | 22 | Bazuca Films | false | false |
| 29 | - | La Vie En Rose | $510 | - | 1 | - | $510 | $182,652 | 30 | Transeuropa | false | false |
| 30 | 29 | Le Sauvage | $419 | -56.4% | 1 | - | $419 | $19,209 | 4 | Four Films | false | false |
| 31 | 30 | 1408 | $343 | -33.8% | 1 | - | $343 | $203,975 | 10 | United International Pictures | false | false |
| 32 | 27 | Gone Baby Gone | $330 | -76% | 2 | -1 | $165 | $29,185 | 6 | Walt Disney Pictures | false | false |
| 33 | - | The Mudboy | $164 | - | 2 | - | $82 | $164 | 1 | Walt Disney Pictures | true | false |
| 34 | 20 | In the Land of Women | $106 | -97.7% | 1 | -5 | $106 | $7,326 | 2 | CDI Films | false | false |
| 35 | 34 | The Golden Compass | $97 | -23.6% | 1 | - | $97 | $849,398 | 12 | Warner Bros. | false | false |
