| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 3 | The Water Horse | $93,698 | -0.7% | 25 | +1 | $3,747 | $245,438 | 2 | Sony Pictures Releasing | false | false |
| 2 | 4 | The Game Plan | $88,723 | +12.3% | 22 | +2 | $4,032 | $649,718 | 5 | Walt Disney Pictures | false | false |
| 3 | 1 | Cloverfield | $81,942 | -13.9% | 28 | - | $2,926 | $229,969 | 2 | United International Pictures | false | false |
| 4 | 2 | Sweeney Todd: The Demon Barber of Fleet Street | $79,350 | -16.3% | 15 | - | $5,290 | $234,293 | 2 | Warner Bros. | false | false |
| 5 | 5 | I Am Legend | $72,709 | +1.2% | 39 | - | $1,864 | $1,156,553 | 5 | Warner Bros. | false | false |
| 6 | - | P.S. I Love You | $69,094 | - | 19 | - | $3,636 | $69,094 | 1 | Bazuca Films | true | false |
| 7 | - | Atonement | $56,048 | - | 14 | - | $4,003 | $67,923 | 1 | United International Pictures | true | false |
| 8 | 6 | The Bucket List | $52,043 | -15.4% | 16 | -2 | $3,252 | $282,084 | 3 | Warner Bros. | false | false |
| 9 | - | No Country for Old Men | $48,613 | - | 11 | - | $4,419 | $61,369 | 1 | United International Pictures | true | false |
| 10 | 7 | 27 Dresses | $37,543 | -27.6% | 24 | -1 | $1,564 | $122,073 | 2 | 20th Century Fox International | false | false |
| 11 | - | Good Luck Chuck | $36,427 | - | 15 | - | $2,428 | $36,427 | 1 | Sony Pictures Releasing | true | false |
| 12 | 8 | Aliens vs. Predator: Requiem | $21,157 | -37.8% | 20 | -12 | $1,057 | $392,980 | 4 | 20th Century Fox International | false | false |
| 13 | 11 | Love in the Time of Cholera | $18,811 | +10.9% | 15 | +5 | $1,254 | $328,998 | 5 | 20th Century Fox International | false | false |
| 14 | 9 | Enchanted | $15,637 | -40.3% | 20 | -10 | $781 | $1,358,433 | 10 | Walt Disney Pictures | false | false |
| 15 | 12 | Alvin and the Chipmunks | $10,986 | -18.7% | 15 | -7 | $732 | $816,356 | 9 | 20th Century Fox International | false | false |
| 16 | 10 | National Treasure: Book of Secrets | $9,896 | -50.4% | 7 | -18 | $1,413 | $990,943 | 8 | Walt Disney Pictures | false | false |
| 17 | 13 | Hannibal Rising | $7,992 | -16% | 9 | - | $888 | $67,141 | 3 | United International Pictures | false | false |
| 18 | 16 | Beowulf | $4,064 | <0.1% | 1 | - | $4,064 | $674,412 | 13 | Warner Bros. | false | false |
| 19 | 14 | Michael Clayton | $4,048 | -31.7% | 2 | -2 | $2,024 | $184,579 | 11 | Bazuca Films | false | false |
| 20 | 15 | Private Fears in Public Places | $2,621 | -48.9% | 1 | -2 | $2,621 | $41,720 | 4 | Four Films | false | false |
| 21 | - | Radio Corazón | $2,157 | - | 1 | - | $2,157 | $1,898,609 | 20 | Bazuca Films | false | false |
| 22 | - | Papelucho y el marciano | $2,157 | - | 1 | - | $2,157 | $945,340 | 40 | Bazuca Films | false | false |
| 23 | 21 | Chile puede | $1,970 | +13.7% | 1 | - | $1,970 | $365,966 | 7 | Warner Bros. | false | false |
| 24 | - | Gone Baby Gone | $1,767 | - | 3 | - | $589 | $24,281 | 4 | Walt Disney Pictures | false | false |
| 25 | 24 | Hitman | $1,456 | +3.2% | 3 | - | $485 | $99,146 | 6 | 20th Century Fox International | false | false |
| 26 | - | Priceless | $1,202 | - | 3 | - | $400 | $38,158 | 6 | Transeuropa | false | false |
| 27 | 17 | Le Sauvage | $866 | -70.5% | 2 | -4 | $433 | $6,294 | 2 | Four Films | false | false |
| 28 | 23 | 30 Days of Night | $851 | -44.1% | 1 | -3 | $851 | $111,602 | 6 | Sony Pictures Releasing | false | false |
| 29 | 19 | School for Scoundrels | $759 | -63% | 2 | -3 | $379 | $38,687 | 3 | Bazuca Films | false | false |
| 30 | 22 | Bridge to Terabithia | $635 | -62.9% | 1 | -3 | $635 | $56,408 | 7 | United International Pictures | false | false |
| 31 | - | The Assassination of Jesse James by the Coward Robert Ford | $609 | - | 2 | - | $304 | $55,512 | 8 | Warner Bros. | false | false |
| 32 | 18 | The Heartbreak Kid | $443 | -82.1% | 1 | -3 | $443 | $481,654 | 9 | United International Pictures | false | false |
| 33 | 27 | Sleuth | $217 | -44.9% | 1 | - | $217 | $21,799 | 6 | Sony Pictures Releasing | false | false |
| 34 | 25 | The Golden Compass | $217 | -84% | 1 | -2 | $217 | $832,759 | 10 | Warner Bros. | false | false |
| 35 | 30 | Lie with Me | $181 | +432.4% | 1 | - | $181 | $14,097 | 4 | - | false | false |
