| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | National Treasure: Book of Secrets | $216,293 | - | 89 | - | $2,430 | $765,500 | 2 | Ster-Kinekor Pictures | false | false |
| 2 | - | I Am Legend | $92,976 | - | 66 | - | $1,408 | $1,617,918 | 4 | NuMetro Distribution | false | false |
| 3 | - | Saw IV | $92,493 | - | 40 | - | $2,312 | $92,493 | 1 | Ster-Kinekor Pictures | true | false |
| 4 | - | Alvin and the Chipmunks | $64,651 | - | 53 | - | $1,219 | $797,978 | 4 | NuMetro Distribution | false | false |
| 5 | - | Elizabeth: The Golden Age | $64,512 | - | 28 | - | $2,304 | $64,512 | 1 | United International Pictures | true | false |
| 6 | - | Enchanted | $60,504 | - | 68 | - | $889 | $1,335,779 | 5 | Ster-Kinekor Pictures | false | false |
| 7 | - | We Own the Night | $44,854 | - | 57 | - | $786 | $416,039 | 3 | United International Pictures | false | false |
| 8 | - | Griffin & Phoenix | $28,875 | - | 33 | - | $875 | $28,875 | 1 | NuMetro Distribution | true | false |
| 9 | - | Martian Child | $27,751 | - | 25 | - | $1,110 | $27,751 | 1 | NuMetro Distribution | true | false |
| 10 | - | American Gangster | $22,757 | - | 32 | - | $711 | $788,850 | 7 | United International Pictures | false | false |
| 11 | - | Bee Movie | $21,578 | - | 46 | - | $469 | $1,377,974 | 6 | United International Pictures | false | false |
| 12 | - | Hitman | $21,100 | - | 31 | - | $680 | $699,989 | 6 | NuMetro Distribution | false | false |
| 13 | - | Aliens vs. Predator: Requiem | $18,604 | - | 32 | - | $581 | $239,671 | 3 | NuMetro Distribution | false | false |
| 14 | - | August Rush | $17,571 | - | 16 | - | $1,098 | $234,125 | 4 | NuMetro Distribution | false | false |
| 15 | - | The Darjeeling Limited | $17,568 | - | 12 | - | $1,464 | $17,568 | 1 | NuMetro Distribution | true | false |
| 16 | - | The Jane Austen Book Club | $16,459 | - | 12 | - | $1,371 | $127,651 | 3 | Ster-Kinekor Pictures | false | false |
| 17 | - | Evening | $15,029 | - | 16 | - | $939 | $76,723 | 2 | Ster-Kinekor Pictures | false | false |
| 18 | - | La Vie En Rose | $8,189 | - | 6 | - | $1,364 | $124,057 | 6 | Ster-Kinekor Pictures | false | false |
| 19 | - | Underdog | $8,118 | - | 9 | - | $902 | $58,734 | 3 | Ster-Kinekor Pictures | false | false |
| 20 | - | Like Stars on Earth | $7,267 | - | 5 | - | $1,453 | $79,506 | 5 | Ster-Kinekor Pictures | false | false |
| 21 | - | This Christmas | $3,709 | - | 10 | - | $370 | $160,122 | 5 | Ster-Kinekor Pictures | false | false |
| 22 | - | 30 Days of Night | $2,755 | - | 7 | - | $393 | $283,884 | 6 | United International Pictures | false | false |
| 23 | - | The Heartbreak Kid | $2,414 | - | 5 | - | $482 | $900,362 | 10 | United International Pictures | false | false |
| 24 | - | The Kingdom | $668 | - | 2 | - | $334 | $489,968 | 11 | United International Pictures | false | false |
| 25 | - | Surf's Up | $602 | - | 5 | - | $120 | $1,189,456 | 8 | Ster-Kinekor Pictures | false | false |
| 26 | - | Daddy Day Camp | $199 | - | 1 | - | $199 | $196,852 | 16 | Ster-Kinekor Pictures | false | false |
| 27 | - | 3:10 to Yuma | $157 | - | 1 | - | $157 | $77,264 | 12 | Ster-Kinekor Pictures | false | false |
