| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | The Kite Runner | $738,085 | +12.1% | 65 | - | $11,355 | $1,680,474 | 2 | Universal Pictures International (UPI) | false | false |
| 2 | 1 | National Treasure: Book of Secrets | $541,133 | -23.9% | 115 | - | $4,705 | $1,454,222 | 2 | Walt Disney Pictures | false | false |
| 3 | 3 | Killer Babes | $388,837 | -14.3% | 86 | - | $4,521 | $3,752,797 | 5 | Independent Films | false | false |
| 4 | 4 | I Am Legend | $256,342 | -29% | 94 | -1 | $2,727 | $5,630,908 | 5 | Warner Bros. | false | false |
| 5 | - | Aliens vs. Predator: Requiem | $234,769 | - | 49 | - | $4,791 | $234,769 | 1 | 20th Century Fox International | true | false |
| 6 | 8 | Bee Movie | $154,263 | +3.3% | 109 | - | $1,415 | $38,978,198 | 6 | Universal Pictures International (UPI) | false | false |
| 7 | 6 | Love Is All | $139,309 | -17.7% | 87 | -5 | $1,601 | $14,174,110 | 15 | A-Film Distribution | false | false |
| 8 | - | Gone Baby Gone | $103,303 | - | 22 | - | $4,695 | $126,896 | 1 | Walt Disney Pictures | true | false |
| 9 | 5 | Saw IV | $103,129 | -44.4% | 60 | - | $1,718 | $905,824 | 3 | Benelux Film Distributors | false | false |
| 10 | 7 | The Golden Compass | $101,061 | -32.9% | 119 | -17 | $849 | $3,932,417 | 7 | RCV Film Distribution | false | false |
| 11 | 11 | K3 en de kattenprins | $93,730 | -4.1% | 101 | -4 | $928 | $1,662,276 | 5 | Independent Films | false | false |
| 12 | 9 | Earth | $91,178 | -16.5% | 30 | - | $3,039 | $1,414,933 | 8 | Independent Films | false | false |
| 13 | 10 | Enchanted | $83,341 | -19.7% | 121 | -12 | $688 | $2,164,562 | 6 | Walt Disney Pictures | false | false |
| 14 | 13 | P.S. I Love You | $59,272 | -17.3% | 31 | -4 | $1,912 | $700,934 | 5 | Independent Films | false | false |
| 15 | 14 | Storm Bound | $54,933 | -9.3% | 84 | -6 | $653 | $1,765,759 | 9 | RCV Film Distribution | false | false |
| 16 | 16 | Atonement | $51,801 | +27.4% | 24 | - | $2,158 | $1,524,972 | 12 | Universal Pictures International (UPI) | false | false |
| 17 | 12 | Elizabeth: The Golden Age | $47,337 | -38.3% | 44 | - | $1,075 | $950,738 | 5 | Universal Pictures International (UPI) | false | false |
| 18 | 17 | Mr. Magorium's Wonder Emporium | $42,933 | +28.1% | 52 | -8 | $825 | $764,466 | 7 | Benelux Film Distributors | false | false |
| 19 | - | The Flock | $32,520 | - | 15 | - | $2,168 | $36,996 | 1 | RCV Film Distribution | true | false |
| 20 | 15 | The Nanny Diaries | $31,156 | -34.8% | 15 | -5 | $2,077 | $172,461 | 2 | Paradiso Entertainment | false | false |
| 21 | - | Hallam Foe | $9,342 | - | 10 | - | $934 | $9,342 | 1 | Moonlight Films | true | false |
| 22 | - | Sleuth | $8,670 | - | 5 | - | $1,734 | $8,670 | 1 | RCV Film Distribution | true | false |
| 23 | - | Caramel | $6,285 | - | 4 | - | $1,571 | $6,285 | 1 | A-Film Distribution | true | false |
| 24 | - | 12 Angry Men 2008 Re-release | $576 | - | 3 | - | $192 | $576 | 1 | Filmmuseum Distributie | true | false |
