| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | I Am Legend | $521,763 | -59.7% | - | - | - | $2,729,386 | 2 | Village Films | false | false |
| 2 | 2 | National Treasure: Book of Secrets | $425,200 | -53.1% | - | - | - | $1,568,490 | 2 | Audio Visual Enterprises | false | false |
| 3 | - | Charlie Wilson's War | $399,058 | - | - | - | - | $399,058 | 1 | United International Pictures | true | false |
| 4 | - | Aliens vs. Predator: Requiem | $183,268 | - | - | - | - | $183,268 | 1 | Odeon | true | false |
| 5 | - | P.S. I Love You | $170,997 | - | - | - | - | $170,997 | 1 | Odeon | true | false |
| 6 | 3 | American Gangster | $166,930 | -61.3% | - | - | - | $2,083,158 | 3 | United International Pictures | false | false |
| 7 | - | The Assassination of Jesse James by the Coward Robert Ford | $145,112 | - | - | - | - | $145,112 | 1 | Village Films | true | false |
| 8 | 5 | Bee Movie | $122,767 | -41.9% | - | - | - | $1,345,207 | 5 | United International Pictures | false | false |
| 9 | 6 | The Orphanage | $85,467 | -43.8% | - | - | - | $1,089,791 | 4 | Odeon | false | false |
| 10 | 8 | Michael Clayton | $63,924 | -7.2% | - | - | - | $429,905 | 4 | Odeon | false | false |
| 11 | 4 | The Golden Compass | $60,819 | -77.4% | - | - | - | $3,101,769 | 4 | Village Films | false | false |
| 12 | 9 | Alvin and the Chipmunks | $31,242 | -30.8% | - | - | - | $301,171 | 5 | Odeon | false | false |
| 13 | - | In the Name of the King: A Dungeon Siege Tale | $24,264 | - | - | - | - | $24,264 | 1 | Hollywood Entertainment | true | false |
| 14 | - | The Reef | $18,064 | - | - | - | - | $372,938 | 9 | Odeon | false | false |
| 15 | 10 | My Blueberry Nights | $17,712 | -46.2% | - | - | - | $448,140 | 4 | Audio Visual Enterprises | false | false |
| 16 | 7 | Dan in Real Life | $15,472 | -80.1% | - | - | - | $335,305 | 3 | Odeon | false | false |
| 17 | - | Elizabeth: The Golden Age | $5,206 | - | - | - | - | $650,837 | 6 | United International Pictures | false | false |
