| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Enchanted | $107,061 | -9% | 35 | - | $3,058 | $826,787 | 5 | Walt Disney Pictures | false | false |
| 2 | 1 | National Treasure: Book of Secrets | $101,827 | -17.8% | 42 | -1 | $2,424 | $554,838 | 3 | Walt Disney Pictures | false | false |
| 3 | 4 | Alvin and the Chipmunks | $69,714 | -14.7% | 34 | +1 | $2,050 | $471,426 | 4 | 20th Century Fox International | false | false |
| 4 | 3 | Chile puede | $61,749 | -37.8% | 40 | - | $1,543 | $224,080 | 2 | Warner Bros. | false | false |
| 5 | 5 | The Golden Compass | $45,504 | -24.4% | 31 | -7 | $1,467 | $658,509 | 5 | Warner Bros. | false | false |
| 6 | 6 | The Heartbreak Kid | $40,590 | -30.4% | 25 | -2 | $1,623 | $348,374 | 4 | United International Pictures | false | false |
| 7 | - | Hitman | $37,692 | - | 19 | - | $1,983 | $37,692 | 1 | 20th Century Fox International | true | false |
| 8 | - | 30 Days of Night | $31,382 | - | 16 | - | $1,961 | $31,382 | 1 | Sony Pictures Releasing | true | false |
| 9 | - | Shattered | $23,820 | - | 19 | - | $1,253 | $23,820 | 1 | Bazuca Films | true | false |
| 10 | 7 | 1408 | $17,480 | -42.1% | 13 | -7 | $1,344 | $122,612 | 3 | United International Pictures | false | false |
| 11 | 8 | Bee Movie | $15,008 | -38.9% | 21 | -8 | $714 | $603,270 | 6 | United International Pictures | false | false |
| 12 | - | Priceless | $14,987 | - | 7 | - | $2,141 | $14,987 | 1 | Transeuropa | true | false |
| 13 | 10 | Pulentos, la película | $10,445 | -41.9% | 15 | -11 | $696 | $114,469 | 3 | Bazuca Films | false | false |
| 14 | 12 | Michael Clayton | $7,651 | -22.5% | 5 | +1 | $1,530 | $128,681 | 6 | Bazuca Films | false | false |
| 15 | 9 | Bridge to Terabithia | $6,856 | -63.3% | 9 | -5 | $761 | $36,821 | 2 | United International Pictures | false | false |
| 16 | 13 | Beowulf | $6,071 | -32.7% | 3 | - | $2,023 | $595,414 | 8 | Warner Bros. | false | false |
| 17 | - | Sleuth | $5,773 | - | 1 | - | $5,773 | $5,773 | 1 | Sony Pictures Releasing | true | false |
| 18 | 11 | Saw IV | $4,985 | -66.5% | 8 | -5 | $623 | $264,986 | 6 | Walt Disney Pictures | false | false |
| 19 | 15 | The Assassination of Jesse James by the Coward Robert Ford | $1,918 | -73.6% | 2 | -4 | $959 | $38,771 | 3 | Warner Bros. | false | false |
| 20 | - | Saint Ange 2006 Re-release | $802 | - | 1 | - | $802 | $129,826 | 12 | Bazuca Films | false | false |
| 21 | 14 | Stormbreaker | $530 | -93.1% | 3 | -5 | $176 | $11,274 | 2 | Impacto Cine | false | false |
| 22 | 19 | Orchestra Seats | $388 | -24.1% | 1 | - | $388 | $72,103 | 10 | Transeuropa | false | false |
