| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | National Treasure: Book of Secrets | $539,988 | -52.6% | 75 | - | $7,199 | $1,800,364 | 2 | Walt Disney Pictures | false | false |
| 2 | 2 | I Am Legend | $316,709 | -52.8% | 66 | - | $4,798 | $4,120,866 | 4 | Warner Bros. | false | false |
| 3 | - | Atonement | $195,805 | - | 20 | - | $9,790 | $283,389 | 1 | Universal Pictures International (UPI) | true | false |
| 4 | 3 | Alvin and the Chipmunks | $189,440 | -60.5% | 71 | - | $2,668 | $1,547,318 | 4 | 20th Century Fox International | false | false |
| 5 | 4 | Enchanted | $156,229 | -66.6% | 83 | -8 | $1,882 | $2,218,485 | 4 | Walt Disney Pictures | false | false |
| 6 | - | Into the Wild | $153,565 | - | 13 | - | $11,812 | $153,565 | 1 | Alternative Films | true | false |
| 7 | 6 | The Golden Compass | $141,226 | -63.8% | 90 | -15 | $1,569 | $3,137,308 | 6 | Kinepolis Film Distribution (KFD) | false | false |
| 8 | 5 | Bee Movie | $121,226 | -73.5% | 91 | -7 | $1,332 | $2,920,824 | 5 | Universal Pictures International (UPI) | false | false |
| 9 | - | 30 Days of Night | $115,720 | - | 30 | - | $3,857 | $119,599 | 1 | Benelux Film Distributors | true | false |
| 10 | - | Rendition | $107,564 | - | 24 | - | $4,481 | $121,295 | 1 | Kinepolis Film Distribution (KFD) | true | false |
| 11 | 8 | Saw IV | $100,121 | -53.4% | 34 | -1 | $2,944 | $1,016,079 | 3 | Les Films de l'Elysée | false | false |
| 12 | 7 | K3 en de kattenprins | $74,020 | -71.9% | 36 | - | $2,056 | $841,214 | 4 | Kinepolis Film Distribution (KFD) | false | false |
| 13 | 9 | Gone Baby Gone | $67,025 | -49.1% | 38 | -1 | $1,763 | $496,541 | 3 | Walt Disney Pictures | false | false |
| 14 | 11 | Elizabeth: The Golden Age | $52,814 | -51.4% | 36 | - | $1,467 | $920,948 | 5 | Universal Pictures International (UPI) | false | false |
| 15 | 10 | Good Luck Chuck | $51,399 | -54.7% | 11 | - | $4,672 | $443,023 | 4 | Sony Pictures Releasing | false | false |
| 16 | 13 | American Gangster | $31,009 | -43.8% | 18 | -11 | $1,722 | $2,167,807 | 9 | Universal Pictures International (UPI) | false | false |
| 17 | 15 | Eastern Promises | $27,774 | -41.2% | 17 | - | $1,633 | $755,472 | 7 | Kinepolis Film Distribution (KFD) | false | false |
| 18 | 16 | Cassandra's Dream | $27,254 | -35.9% | 14 | -3 | $1,946 | $212,503 | 3 | Cinéart | false | false |
| 19 | - | Room of Death | $19,313 | - | 15 | - | $1,287 | $75,030 | 1 | Cinéart | true | false |
| 20 | 17 | Hitman | $17,908 | -55.7% | 27 | - | $663 | $1,004,559 | 7 | 20th Century Fox International | false | false |
| 21 | 12 | Mr. Magorium's Wonder Emporium | $16,947 | -72.2% | 22 | -7 | $770 | $195,275 | 3 | Benelux Film Distributors | false | false |
| 22 | 18 | Two Worlds | $16,414 | -56.6% | 8 | -1 | $2,051 | $837,934 | 8 | Benelux Film Distributors | false | false |
| 23 | 23 | My Blueberry Nights | $15,906 | -39.3% | 15 | - | $1,060 | $323,372 | 6 | Cinéart | false | false |
| 24 | 25 | Killer Babes | $15,168 | -32.4% | 3 | - | $5,056 | $87,221 | 4 | N/A | false | false |
| 25 | 34 | The Edge of Heaven | $14,297 | +6% | 9 | -1 | $1,588 | $309,538 | 9 | Cinéart | false | false |
| 26 | 26 | The Secret of the Grain | $14,078 | -36.9% | 5 | - | $2,815 | $118,758 | 5 | Alternative Films | false | false |
| 27 | 20 | Missing Persons Unit | $13,653 | -60.1% | 15 | -4 | $910 | $1,922,523 | 11 | Kinepolis Film Distribution (KFD) | false | false |
| 28 | 19 | The Fox and the Child | $13,398 | -61.8% | 13 | -3 | $1,030 | $178,315 | 5 | Paradiso Entertainment | false | false |
| 29 | 21 | Surviving with Wolves | $12,293 | -61.7% | 15 | -10 | $819 | $544,012 | 8 | Victory Productions | false | false |
| 30 | 24 | Cow-Boy | $11,311 | -55.8% | 15 | -5 | $754 | $356,847 | 6 | Belga Films | false | false |
| 31 | 14 | Beowulf | $10,367 | -78.2% | 11 | -4 | $942 | $1,497,691 | 8 | Warner Bros. | false | false |
| 32 | - | Dante 01 | $9,439 | - | 5 | - | $1,887 | $18,876 | 1 | Les Films de l'Elysée | true | false |
| 33 | 36 | Ben X | $8,921 | -26.2% | 15 | +4 | $594 | $2,275,729 | 16 | Kinepolis Film Distribution (KFD) | false | false |
| 34 | - | California Dreamin' | $8,554 | - | 7 | - | $1,222 | $9,745 | 1 | Benelux Film Distributors | true | false |
| 35 | 33 | We Own the Night | $8,524 | -41.8% | 6 | -7 | $1,420 | $396,756 | 7 | Paradiso Entertainment | false | false |
| 36 | 27 | Becoming Jane | $8,124 | -62.1% | 7 | -4 | $1,160 | $133,570 | 3 | A-Film Distribution | false | false |
| 37 | - | The Key | $7,927 | - | 6 | - | $1,321 | $33,085 | 2 | Les Films de l'Elysée | false | false |
| 38 | 22 | The Return | $5,369 | -82.5% | 8 | -3 | $671 | $116,219 | 2 | Universal Pictures International (UPI) | false | false |
| 39 | 40 | The Kingdom | $5,251 | -39.8% | 2 | -2 | $2,625 | $890,001 | 11 | Universal Pictures International (UPI) | false | false |
| 40 | 42 | Mr. Brooks | $4,884 | -30.7% | 1 | - | $4,884 | $604,012 | 13 | Kinepolis Film Distribution (KFD) | false | false |
| 41 | 28 | Go West: A Lucky Luke Adventure | $4,725 | -77.1% | 11 | -7 | $429 | $141,930 | 6 | Alternative Films | false | false |
| 42 | 38 | Ratatouille | $4,031 | -64.7% | 3 | -3 | $1,343 | $8,904,399 | 24 | Buena Vista International | false | false |
| 43 | 29 | Big City | $3,794 | -79.4% | 2 | -19 | $1,897 | $89,022 | 4 | N/A | false | false |
| 44 | 30 | Underdog | $2,878 | -82.3% | 11 | -8 | $261 | $477,280 | 8 | Walt Disney Pictures | false | false |
| 45 | 43 | Silent Light | $2,596 | -54.3% | 4 | +1 | $649 | $19,949 | 6 | Benelux Film Distributors | false | false |
| 46 | - | Cabale à Kaboul | $2,476 | - | 2 | - | $1,238 | $2,631 | 1 | N/A | true | false |
| 47 | 47 | The Grocer's Son | $2,101 | -37.3% | 4 | -2 | $525 | $63,998 | 7 | Benelux Film Distributors | false | false |
| 48 | 45 | Surf's Up | $2,055 | -50.8% | 3 | -1 | $685 | $857,748 | 12 | Sony Pictures Releasing | false | false |
| 49 | 41 | Plop en de pinguïn | $2,007 | -72.8% | 2 | -3 | $1,003 | $1,053,664 | 13 | Kinepolis Film Distribution (KFD) | false | false |
| 50 | 48 | The Bourne Ultimatum | $1,697 | -27.8% | 2 | - | $848 | $3,097,665 | 18 | Universal Pictures International (UPI) | false | false |
| 51 | - | Rush Hour 3 | $1,528 | - | 1 | - | $1,528 | $1,536,428 | 13 | Paradiso Entertainment | false | false |
| 52 | 49 | You, the Living | $1,370 | +4.9% | 3 | - | $456 | $44,828 | 8 | Benelux Film Distributors | false | false |
| 53 | - | Control | $956 | - | 2 | - | $478 | $142,995 | 18 | Paradiso Entertainment | false | false |
| 54 | - | Willy and Wild Rabbit | $441 | - | 1 | - | $441 | $762 | 1 | Jekino | true | false |
